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glycerol-3-phosphate dehydrogenase 1 like

Summary

Gene Symbol

GPD1L

Organism

Pan troglodytes (chimpanzee)

External Links

NCBI Gene: 750218
KEGG Gene ID: ptr:750218
PubChem: 750218

Annotation

Keyword

NAD
Oxidoreductase
Reference proteome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A6D2XJI4
K7CYD7

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
glycerol-3-phosphate catabolic process	IEA	22301074
carbohydrate metabolic process	IEA	22301074

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

organic substance catabolic process [inference]

organophosphate catabolic process [inference]

glycerol-3-phosphate catabolic process

carbohydrate derivative catabolic process [inference]

glycerol-3-phosphate catabolic process

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

alditol phosphate metabolic process [inference]

glycerol-3-phosphate metabolic process [inference]

glycerol-3-phosphate catabolic process

organophosphate metabolic process [inference]

organophosphate catabolic process [inference]

glycerol-3-phosphate catabolic process

alditol phosphate metabolic process [inference]

glycerol-3-phosphate metabolic process [inference]

glycerol-3-phosphate catabolic process

primary metabolic process [inference]

carbohydrate metabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process

organophosphate metabolic process [inference]

organophosphate catabolic process [inference]

glycerol-3-phosphate catabolic process

alditol phosphate metabolic process [inference]

glycerol-3-phosphate metabolic process [inference]

glycerol-3-phosphate catabolic process

carbohydrate derivative metabolic process [inference]

alditol phosphate metabolic process [inference]

glycerol-3-phosphate metabolic process [inference]

glycerol-3-phosphate catabolic process

carbohydrate derivative catabolic process [inference]

glycerol-3-phosphate catabolic process

organic substance catabolic process [inference]

organophosphate catabolic process [inference]

glycerol-3-phosphate catabolic process

carbohydrate derivative catabolic process [inference]

glycerol-3-phosphate catabolic process

cellular process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

alditol phosphate metabolic process [inference]

glycerol-3-phosphate metabolic process [inference]

glycerol-3-phosphate catabolic process

organophosphate metabolic process [inference]

organophosphate catabolic process [inference]

glycerol-3-phosphate catabolic process

alditol phosphate metabolic process [inference]

glycerol-3-phosphate metabolic process [inference]

glycerol-3-phosphate catabolic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
glycerol-3-phosphate dehydrogenase complex	IEA	22301074
cytosol	IEA	30032202

GO Hierarchy

cellular component

protein-containing complex [inference]

catalytic complex [inference]

oxidoreductase complex [inference]

glycerol-3-phosphate dehydrogenase complex

cellular anatomical entity [inference]

cytosol

Displaying **all 3** entries
GO Term	Evidence Code	PMID
NAD binding	IEA	22301074
glycerol-3-phosphate dehydrogenase [NAD(P)+] activity	IEA	22301074
protein homodimerization activity	IEA	22301074

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on CH-OH group of donors [inference]

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

glycerol-3-phosphate dehydrogenase [NAD(P)+] activity

binding [inference]

protein binding [inference]

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NAD binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NAD binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Hominidae

Group Name

Glycerol-3-phosphate dehydrogenase, NAD-dependent

Functional Category

C: Energy production and conversion
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying entries **1 - 10** of 16 in total

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Gene Ontology
NAD metabolic process
NADH metabolic process
glycerol-3-phosphate catabolic process
glycerol-3-phosphate metabolic process
negative regulation of peptidyl-serine phosphorylation
negative regulation of protein kinase C signaling
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
oxidoreductase activity
positive regulation of protein localization to cell surface
positive regulation of sodium ion transport

Displaying **all 7** entries
InterPro
6-phosphogluconate dehydrogenase, domain 2
6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily
Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal
Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal
Glycerol-3-phosphate dehydrogenase, NAD-dependent, eukaryotic
Glycerol-3-phosphate dehydrogenase, NAD-dependent
NAD(P)-binding domain superfamily

KEGG BRITE Database

Orthology

K00006

Name

glycerol-3-phosphate dehydrogenase (NAD+) [EC:1.1.1.8]

References

8196651

Rhea

NAD⁺ + sn-glycerol 3-phosphate

H⁺ + dihydroxyacetone phosphate + NADH

Enzyme

PMID

Ortholog

Displaying entries **1 - 10** of 64 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	23171	9606_1:000fa4		HUMAN69018
Mus musculus	333433			MOUSE63829
Rattus norvegicus	363159			RATNO42016
Danio rerio	449663			DANRE10161
Bos taurus	514456			BOVIN17192
Macaca mulatta	707723			MACMU29299
Equus caballus	100057124			HORSE11139
Ornithorhynchus anatinus	100077586			ORNAN25561
Pongo abelii	100173675	9601_0:0011a1		PONAB25706
Ciona intestinalis	100181104			CIOIN08987

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Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024