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tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon

Summary

Gene Symbol

YWHAE

Organism

Homo sapiens (human)

External Links

NCBI Gene

7531

PubChem

7531

Alliance of Genome Resources

HGNC:12851

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Cytoplasm
Direct protein sequencing
Host-virus interaction
Isopeptide bond
Nucleus
Phosphoprotein
Reference proteome
Ubl conjugation

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P62258
V9HW98

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 28 in total

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GO Term	Evidence Code	PMID
MAPK cascade	IDA	12917326
neuron migration	IEA
cytoplasmic pattern recognition receptor signaling pathway	IDA	22607805
regulation of heart rate by hormone	NAS	11953308
protein targeting	IEA

GO Hierarchy

biological process

immune system process [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway

cellular process [inference]

signal transduction

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway

intracellular receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway

intracellular signal transduction

MAPK cascade

cell motility [inference]

cell migration [inference]

neuron migration

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization

protein localization to organelle [inference]

establishment of protein localization [inference]

protein targeting

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to heat

developmental process [inference]

anatomical structure development [inference]

neural nucleus development [inference]

substantia nigra development

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration

intracellular potassium ion homeostasis

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration

intracellular potassium ion homeostasis

monoatomic cation homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration

intracellular potassium ion homeostasis

calcium ion homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration

potassium ion homeostasis [inference]

intracellular potassium ion homeostasis

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration

intracellular potassium ion homeostasis

inorganic ion homeostasis [inference]

calcium ion homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration

potassium ion homeostasis [inference]

intracellular potassium ion homeostasis

response to stimulus [inference]

response to stress [inference]

response to heat [inference]

cellular response to heat

cellular response to stress [inference]

cellular response to heat

response to abiotic stimulus [inference]

response to temperature stimulus [inference]

response to heat [inference]

cellular response to heat

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to heat

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization

protein localization to organelle [inference]

establishment of protein localization [inference]

protein targeting

establishment of localization [inference]

establishment of protein localization [inference]

protein targeting

maintenance of location [inference]

maintenance of protein location [inference]

cytoplasmic sequestering of protein

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization

protein localization to organelle [inference]

establishment of protein localization [inference]

protein targeting

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

negative regulation of immune system process [inference]

negative regulation of toll-like receptor signaling pathway

positive regulation of immune system process [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor signaling pathway [inference]

negative regulation of toll-like receptor signaling pathway

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway

regulation of metabolic process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of peptidyl-serine dephosphorylation

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of peptidyl-serine dephosphorylation

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of peptidyl-serine dephosphorylation

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of peptidyl-serine dephosphorylation

regulation of phosphorus metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of peptidyl-serine dephosphorylation

regulation of phosphate metabolic process [inference]

regulation of dephosphorylation [inference]

regulation of protein dephosphorylation [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of peptidyl-serine dephosphorylation

regulation of peptidyl-serine dephosphorylation [inference]

negative regulation of peptidyl-serine dephosphorylation

negative regulation of dephosphorylation [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of peptidyl-serine dephosphorylation

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of peptidyl-serine dephosphorylation

regulation of nitrogen compound metabolic process [inference]

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of peptidyl-serine dephosphorylation

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of peptidyl-serine dephosphorylation

regulation of protein dephosphorylation [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of peptidyl-serine dephosphorylation

regulation of peptidyl-serine dephosphorylation [inference]

negative regulation of peptidyl-serine dephosphorylation

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of peptidyl-serine dephosphorylation

regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of peptidyl-serine dephosphorylation

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of peptidyl-serine dephosphorylation

regulation of protein dephosphorylation [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of peptidyl-serine dephosphorylation

regulation of peptidyl-serine dephosphorylation [inference]

negative regulation of peptidyl-serine dephosphorylation

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of peptidyl-serine dephosphorylation

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of peptidyl-serine dephosphorylation

regulation of protein dephosphorylation [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of peptidyl-serine dephosphorylation

regulation of peptidyl-serine dephosphorylation [inference]

negative regulation of peptidyl-serine dephosphorylation

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of peptidyl-serine dephosphorylation

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of hippo signaling

negative regulation of signal transduction [inference]

negative regulation of toll-like receptor signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor signaling pathway [inference]

negative regulation of toll-like receptor signaling pathway

regulation of intracellular signal transduction [inference]

regulation of hippo signaling [inference]

positive regulation of hippo signaling

positive regulation of intracellular signal transduction [inference]

positive regulation of hippo signaling

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of hippo signaling

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of toll-like receptor signaling pathway

regulation of localization [inference]

regulation of transport [inference]

regulation of intracellular transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of nucleocytoplasmic transport [inference]

positive regulation of protein export from nucleus

positive regulation of intracellular protein transport [inference]

positive regulation of protein export from nucleus

regulation of intracellular protein transport [inference]

regulation of protein export from nucleus [inference]

positive regulation of protein export from nucleus

positive regulation of intracellular protein transport [inference]

positive regulation of protein export from nucleus

regulation of nucleocytoplasmic transport [inference]

positive regulation of nucleocytoplasmic transport [inference]

positive regulation of protein export from nucleus

regulation of protein export from nucleus [inference]

positive regulation of protein export from nucleus

regulation of transmembrane transport [inference]

regulation of transmembrane transporter activity [inference]

regulation of monoatomic ion transmembrane transporter activity [inference]

regulation of potassium ion transmembrane transporter activity

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion export across plasma membrane

regulation of monoatomic ion transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion export across plasma membrane

regulation of monoatomic cation transmembrane transport [inference]

regulation of potassium ion transmembrane transport

regulation of potassium ion transmembrane transporter activity

regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion export across plasma membrane

regulation of calcium ion export across plasma membrane [inference]

negative regulation of calcium ion export across plasma membrane

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion export across plasma membrane

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of potassium ion transport [inference]

regulation of potassium ion transmembrane transport

regulation of potassium ion transmembrane transporter activity

regulation of calcium ion transport [inference]

negative regulation of calcium ion transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion export across plasma membrane

regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion export across plasma membrane

regulation of calcium ion export across plasma membrane [inference]

negative regulation of calcium ion export across plasma membrane

regulation of monoatomic ion transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion export across plasma membrane

regulation of monoatomic cation transmembrane transport [inference]

regulation of potassium ion transmembrane transport

regulation of potassium ion transmembrane transporter activity

regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion export across plasma membrane

regulation of calcium ion export across plasma membrane [inference]

negative regulation of calcium ion export across plasma membrane

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion export across plasma membrane

negative regulation of monoatomic ion transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion export across plasma membrane

negative regulation of calcium ion transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion export across plasma membrane

positive regulation of transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of nucleocytoplasmic transport [inference]

positive regulation of protein export from nucleus

positive regulation of intracellular protein transport [inference]

positive regulation of protein export from nucleus

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport [inference]

positive regulation of protein export from nucleus

negative regulation of transport [inference]

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion export across plasma membrane

negative regulation of monoatomic ion transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion export across plasma membrane

negative regulation of calcium ion transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion export across plasma membrane

regulation of protein transport [inference]

regulation of intracellular protein transport [inference]

regulation of protein export from nucleus [inference]

positive regulation of protein export from nucleus

positive regulation of intracellular protein transport [inference]

positive regulation of protein export from nucleus

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport [inference]

positive regulation of protein export from nucleus

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of nucleocytoplasmic transport [inference]

positive regulation of protein export from nucleus

positive regulation of intracellular protein transport [inference]

positive regulation of protein export from nucleus

regulation of intracellular protein transport [inference]

regulation of protein export from nucleus [inference]

positive regulation of protein export from nucleus

positive regulation of intracellular protein transport [inference]

positive regulation of protein export from nucleus

regulation of nucleocytoplasmic transport [inference]

positive regulation of nucleocytoplasmic transport [inference]

positive regulation of protein export from nucleus

regulation of protein export from nucleus [inference]

positive regulation of protein export from nucleus

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of intracellular protein transport [inference]

regulation of protein export from nucleus [inference]

positive regulation of protein export from nucleus

positive regulation of intracellular protein transport [inference]

positive regulation of protein export from nucleus

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport [inference]

positive regulation of protein export from nucleus

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport [inference]

positive regulation of protein export from nucleus

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport [inference]

positive regulation of protein export from nucleus

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of hippo signaling

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of hippo signaling

positive regulation of intracellular transport [inference]

positive regulation of nucleocytoplasmic transport [inference]

positive regulation of protein export from nucleus

positive regulation of intracellular protein transport [inference]

positive regulation of protein export from nucleus

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport [inference]

positive regulation of protein export from nucleus

positive regulation of response to stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of hippo signaling

positive regulation of defense response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway

positive regulation of transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of nucleocytoplasmic transport [inference]

positive regulation of protein export from nucleus

positive regulation of intracellular protein transport [inference]

positive regulation of protein export from nucleus

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport [inference]

positive regulation of protein export from nucleus

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of toll-like receptor signaling pathway

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of peptidyl-serine dephosphorylation

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of peptidyl-serine dephosphorylation

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of peptidyl-serine dephosphorylation

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of toll-like receptor signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of toll-like receptor signaling pathway

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of peptidyl-serine dephosphorylation

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion export across plasma membrane

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of toll-like receptor signaling pathway

negative regulation of transport [inference]

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion export across plasma membrane

negative regulation of monoatomic ion transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion export across plasma membrane

negative regulation of calcium ion transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion export across plasma membrane

regulation of response to stimulus [inference]

regulation of response to biotic stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor signaling pathway [inference]

negative regulation of toll-like receptor signaling pathway

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of hippo signaling

negative regulation of signal transduction [inference]

negative regulation of toll-like receptor signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor signaling pathway [inference]

negative regulation of toll-like receptor signaling pathway

regulation of intracellular signal transduction [inference]

regulation of hippo signaling [inference]

positive regulation of hippo signaling

positive regulation of intracellular signal transduction [inference]

positive regulation of hippo signaling

regulation of response to external stimulus [inference]

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor signaling pathway [inference]

negative regulation of toll-like receptor signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of hippo signaling

positive regulation of defense response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of toll-like receptor signaling pathway

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor signaling pathway [inference]

negative regulation of toll-like receptor signaling pathway

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway

regulation of response to stress [inference]

regulation of defense response [inference]

positive regulation of defense response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor signaling pathway [inference]

negative regulation of toll-like receptor signaling pathway

regulation of cellular process [inference]

signal transduction

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway

intracellular receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway

intracellular signal transduction

MAPK cascade

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of hippo signaling

negative regulation of signal transduction [inference]

negative regulation of toll-like receptor signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor signaling pathway [inference]

negative regulation of toll-like receptor signaling pathway

regulation of intracellular signal transduction [inference]

regulation of hippo signaling [inference]

positive regulation of hippo signaling

positive regulation of intracellular signal transduction [inference]

positive regulation of hippo signaling

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of hippo signaling

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of toll-like receptor signaling pathway

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of peptidyl-serine dephosphorylation

regulation of phosphorus metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of peptidyl-serine dephosphorylation

regulation of phosphate metabolic process [inference]

regulation of dephosphorylation [inference]

regulation of protein dephosphorylation [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of peptidyl-serine dephosphorylation

regulation of peptidyl-serine dephosphorylation [inference]

negative regulation of peptidyl-serine dephosphorylation

negative regulation of dephosphorylation [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of peptidyl-serine dephosphorylation

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of peptidyl-serine dephosphorylation

regulation of transmembrane transport [inference]

regulation of transmembrane transporter activity [inference]

regulation of monoatomic ion transmembrane transporter activity [inference]

regulation of potassium ion transmembrane transporter activity

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion export across plasma membrane

regulation of monoatomic ion transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion export across plasma membrane

regulation of monoatomic cation transmembrane transport [inference]

regulation of potassium ion transmembrane transport

regulation of potassium ion transmembrane transporter activity

regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion export across plasma membrane

regulation of calcium ion export across plasma membrane [inference]

negative regulation of calcium ion export across plasma membrane

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion export across plasma membrane

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of hippo signaling

positive regulation of intracellular transport [inference]

positive regulation of nucleocytoplasmic transport [inference]

positive regulation of protein export from nucleus

positive regulation of intracellular protein transport [inference]

positive regulation of protein export from nucleus

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport [inference]

positive regulation of protein export from nucleus

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of toll-like receptor signaling pathway

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of dephosphorylation [inference]

negative regulation of protein dephosphorylation [inference]

negative regulation of peptidyl-serine dephosphorylation

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion export across plasma membrane

regulation of cell cycle [inference]

regulation of mitotic cell cycle

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of nucleocytoplasmic transport [inference]

positive regulation of protein export from nucleus

positive regulation of intracellular protein transport [inference]

positive regulation of protein export from nucleus

regulation of intracellular protein transport [inference]

regulation of protein export from nucleus [inference]

positive regulation of protein export from nucleus

positive regulation of intracellular protein transport [inference]

positive regulation of protein export from nucleus

regulation of nucleocytoplasmic transport [inference]

positive regulation of nucleocytoplasmic transport [inference]

positive regulation of protein export from nucleus

regulation of protein export from nucleus [inference]

positive regulation of protein export from nucleus

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of intracellular protein transport [inference]

regulation of protein export from nucleus [inference]

positive regulation of protein export from nucleus

positive regulation of intracellular protein transport [inference]

positive regulation of protein export from nucleus

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport [inference]

positive regulation of protein export from nucleus

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport [inference]

positive regulation of protein export from nucleus

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport [inference]

positive regulation of protein export from nucleus

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of blood circulation [inference]

regulation of heart contraction [inference]

regulation of heart rate [inference]

regulation of heart rate by chemical signal [inference]

regulation of heart rate by hormone

regulation of heart rate by cardiac conduction

cardiac conduction [inference]

regulation of heart rate by cardiac conduction

regulation of membrane repolarization

regulation of biological quality [inference]

regulation of heart rate [inference]

regulation of heart rate by chemical signal [inference]

regulation of heart rate by hormone

regulation of heart rate by cardiac conduction

regulation of membrane potential [inference]

regulation of membrane repolarization

membrane repolarization [inference]

membrane repolarization during action potential [inference]

membrane repolarization during cardiac muscle cell action potential

cardiac muscle cell membrane repolarization [inference]

membrane repolarization during cardiac muscle cell action potential

regulation of molecular function [inference]

regulation of transporter activity [inference]

regulation of transmembrane transporter activity [inference]

regulation of monoatomic ion transmembrane transporter activity [inference]

regulation of potassium ion transmembrane transporter activity

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GO Term	Evidence Code	PMID
nucleus	IDA	12917326 31906564
cytoplasm	IDA	11118213 12917326
cytoplasm	IBA
endoplasmic reticulum	IDA	35343654
cytosol	TAS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

organelle membrane [inference]

mitochondrial membrane

cell junction [inference]

anchoring junction [inference]

cell-substrate junction [inference]

focal adhesion

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

pigment granule [inference]

melanosome

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

pigment granule [inference]

melanosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

pigment granule [inference]

melanosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying entries **1 - 5** of 22 in total

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GO Term	Evidence Code	PMID
RNA binding	HDA	22658674
protein phosphatase inhibitor activity	IEA
calcium channel regulator activity	IDA	18029012
protein binding	IPI	10644344 11504882 11697890 11784866 12392720 1266503 12917326 14743216 15023544 15696159 15722337 16099986 16189514 16227609 16260042 16306228 16376338 16407301 16511560 16775625 17043677 17085597 17461779 17979178 18045992 18227151 18356162 18458160 18573912 19172738 19331823 19640509 19935711 20562859 20618440 20642453 20936779 21044950 21242966 21282530 21988832 22151054 22246185 22863774 23075850 23275563 23572552 23622247 23752268 24255178 24366813 24725412 24947832 24981860 25036637 25189701 25332407 25588844 25751139 25852190 25959826 26184334 26496610 27030597 27173435 27880917 28514442 28877994 29100370 29106533 29128334 29769719 30611118 31046837 31413325 31980649 32296183 32707033 32814053 33961781 35271311 36096339 36931259 37045861 39251607 7644510
potassium channel regulator activity	IDA	11953308

GO Hierarchy

phosphatase binding [inference]

protein phosphatase binding

histone deacetylase binding

ubiquitin-like protein ligase binding [inference]

ubiquitin protein ligase binding

protein dimerization activity [inference]

protein heterodimerization activity

cell adhesion molecule binding [inference]

cadherin binding

phosphoprotein binding

protein phosphorylated amino acid binding [inference]

phosphoserine residue binding

scaffold protein binding

protein-containing complex binding [inference]

MHC protein complex binding [inference]

MHC class II protein complex binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding

molecular adaptor activity [inference]

protein-macromolecule adaptor activity [inference]

signaling adaptor activity

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme inhibitor activity [inference]

phosphatase inhibitor activity [inference]

protein phosphatase inhibitor activity

phosphatase regulator activity [inference]

phosphatase inhibitor activity [inference]

protein phosphatase inhibitor activity

protein phosphatase regulator activity [inference]

protein phosphatase inhibitor activity

molecular function inhibitor activity [inference]

enzyme inhibitor activity [inference]

phosphatase inhibitor activity [inference]

protein phosphatase inhibitor activity

transporter inhibitor activity [inference]

channel inhibitor activity [inference]

ion channel inhibitor activity [inference]

calcium channel inhibitor activity

transporter regulator activity [inference]

channel regulator activity [inference]

channel inhibitor activity [inference]

ion channel inhibitor activity [inference]

calcium channel inhibitor activity

ion channel regulator activity [inference]

calcium channel regulator activity

calcium channel inhibitor activity

ion channel inhibitor activity [inference]

calcium channel inhibitor activity

potassium channel regulator activity

transporter inhibitor activity [inference]

channel inhibitor activity [inference]

ion channel inhibitor activity [inference]

calcium channel inhibitor activity

molecular sequestering activity [inference]

protein sequestering activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

14-3-3-3

Functional Category

K: Transcription
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 4** entries
InterPro
14-3-3 domain superfamily
14-3-3 domain
14-3-3 protein, conserved site
14-3-3 protein

Ortholog

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	7531	Xenbase:XB-GENE-996375
Mus musculus	22627	Xenbase:XB-GENE-996375	MOUSE03437
Rattus norvegicus	29753		RATNO01074
Bos taurus	282125		BOVIN12484
Danio rerio	322060		DANRE08407
Ciona intestinalis	445611		CIOIN06823
Pan troglodytes	454409		PANTR13169
Danio rerio	503763		DANRE41435
Macaca mulatta	720156		MACMU14211
Ornithorhynchus anatinus	100089523		ORNAN08910

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements