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Guidelines

MIRAGE

cytoskeleton associated protein 5

Summary

Gene Symbol

Ckap5

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

75786

PubChem

75786

Alliance of Genome Resources

MGI:1923036

Annotation

Keyword

Acetylation
Alternative splicing
Centromere
Chromosome
Cytoplasm
Cytoskeleton
Kinetochore
Mitosis
Phosphoprotein
Proteomics identification
Reference proteome
Repeat

Proteins

Displaying **all 3** entries
UniProt	Protein Name
A2AGT5
K3W4R5
A0A0R4J0K2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 26 in total

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GO Term	Evidence Code	PMID
cytoplasmic translation	IDA	23936366
cytoplasmic translation	IMP	23936366
spindle organization	ISO
spindle organization	IEA
mitotic spindle organization	IBA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

translation [inference]

cytoplasmic translation

amide metabolic process [inference]

peptide metabolic process [inference]

peptide biosynthetic process [inference]

translation [inference]

cytoplasmic translation

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

translation [inference]

cytoplasmic translation

organonitrogen compound metabolic process [inference]

peptide metabolic process [inference]

peptide biosynthetic process [inference]

translation [inference]

cytoplasmic translation

protein metabolic process [inference]

translation [inference]

cytoplasmic translation

organonitrogen compound biosynthetic process [inference]

peptide biosynthetic process [inference]

translation [inference]

cytoplasmic translation

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

translation [inference]

cytoplasmic translation

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

translation [inference]

cytoplasmic translation

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

translation [inference]

cytoplasmic translation

organonitrogen compound biosynthetic process [inference]

peptide biosynthetic process [inference]

translation [inference]

cytoplasmic translation

cellular metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

translation [inference]

cytoplasmic translation

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

translation [inference]

cytoplasmic translation

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

translation [inference]

cytoplasmic translation

primary metabolic process [inference]

protein metabolic process [inference]

translation [inference]

cytoplasmic translation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

translation [inference]

cytoplasmic translation

protein metabolic process [inference]

translation [inference]

cytoplasmic translation

organonitrogen compound metabolic process [inference]

peptide metabolic process [inference]

peptide biosynthetic process [inference]

translation [inference]

cytoplasmic translation

protein metabolic process [inference]

translation [inference]

cytoplasmic translation

organonitrogen compound biosynthetic process [inference]

peptide biosynthetic process [inference]

translation [inference]

cytoplasmic translation

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

translation [inference]

cytoplasmic translation

organonitrogen compound biosynthetic process [inference]

peptide biosynthetic process [inference]

translation [inference]

cytoplasmic translation

cellular process [inference]

microtubule-based process [inference]

microtubule cytoskeleton organization [inference]

spindle organization

mitotic spindle organization

establishment or maintenance of microtubule cytoskeleton polarity

microtubule polymerization or depolymerization [inference]

microtubule polymerization

microtubule cytoskeleton organization involved in mitosis [inference]

mitotic spindle organization

microtubule organizing center organization [inference]

centrosome cycle

establishment or maintenance of cell polarity [inference]

establishment or maintenance of cytoskeleton polarity [inference]

establishment or maintenance of microtubule cytoskeleton polarity

cell cycle process [inference]

spindle organization

mitotic spindle organization

mitotic cell cycle process [inference]

microtubule cytoskeleton organization involved in mitosis [inference]

mitotic spindle organization

cellular metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

translation [inference]

cytoplasmic translation

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

translation [inference]

cytoplasmic translation

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

translation [inference]

cytoplasmic translation

cell division

cellular localization [inference]

cellular macromolecule localization [inference]

intracellular mRNA localization [inference]

mRNA localization resulting in post-transcriptional regulation of gene expression

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

microtubule cytoskeleton organization [inference]

spindle organization

mitotic spindle organization

establishment or maintenance of microtubule cytoskeleton polarity

microtubule polymerization or depolymerization [inference]

microtubule polymerization

microtubule cytoskeleton organization involved in mitosis [inference]

mitotic spindle organization

establishment or maintenance of cytoskeleton polarity [inference]

establishment or maintenance of microtubule cytoskeleton polarity

cellular component assembly [inference]

cellular component assembly involved in morphogenesis [inference]

myelin assembly [inference]

central nervous system myelin formation

protein-containing complex assembly [inference]

protein-RNA complex assembly

protein polymerization [inference]

microtubule polymerization

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection organization [inference]

dendritic spine organization [inference]

dendritic spine maintenance

microtubule organizing center organization [inference]

centrosome cycle

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein-RNA complex assembly

protein polymerization [inference]

microtubule polymerization

protein-RNA complex organization [inference]

protein-RNA complex assembly

cellular component maintenance [inference]

dendritic spine maintenance

supramolecular fiber organization [inference]

microtubule polymerization

postsynapse organization [inference]

dendritic spine organization [inference]

dendritic spine maintenance

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

cognition [inference]

learning or memory [inference]

learning [inference]

associative learning [inference]

visual learning

nonassociative learning [inference]

habituation

behavior [inference]

learning or memory [inference]

learning [inference]

associative learning [inference]

visual learning

nonassociative learning [inference]

habituation

locomotory behavior

visual behavior [inference]

visual learning

developmental process [inference]

anatomical structure formation involved in morphogenesis [inference]

cellular component assembly involved in morphogenesis [inference]

myelin assembly [inference]

central nervous system myelin formation

response to stimulus [inference]

response to abiotic stimulus [inference]

response to radiation [inference]

response to light stimulus [inference]

visual behavior [inference]

visual learning

localization [inference]

macromolecule localization [inference]

RNA localization [inference]

intracellular mRNA localization [inference]

mRNA localization resulting in post-transcriptional regulation of gene expression

cellular macromolecule localization [inference]

intracellular mRNA localization [inference]

mRNA localization resulting in post-transcriptional regulation of gene expression

establishment of localization [inference]

transport [inference]

organic substance transport [inference]

nucleobase-containing compound transport [inference]

nucleic acid transport [inference]

RNA transport

nitrogen compound transport [inference]

nucleobase-containing compound transport [inference]

nucleic acid transport [inference]

RNA transport

establishment of RNA localization [inference]

RNA transport

cellular localization [inference]

cellular macromolecule localization [inference]

intracellular mRNA localization [inference]

mRNA localization resulting in post-transcriptional regulation of gene expression

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

mRNA localization resulting in post-transcriptional regulation of gene expression

regulation of cellular metabolic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

mRNA localization resulting in post-transcriptional regulation of gene expression

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

mRNA localization resulting in post-transcriptional regulation of gene expression

regulation of signaling [inference]

positive regulation of signaling [inference]

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic plasticity [inference]

long-term synaptic potentiation

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

regulation of localization [inference]

regulation of transport [inference]

positive regulation of transport [inference]

positive regulation of endocytosis

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of protein polymerization [inference]

positive regulation of microtubule polymerization [inference]

positive regulation of microtubule nucleation

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of cytoskeleton organization [inference]

positive regulation of microtubule polymerization or depolymerization [inference]

positive regulation of microtubule polymerization [inference]

positive regulation of microtubule nucleation

positive regulation of protein-containing complex assembly [inference]

positive regulation of protein polymerization [inference]

positive regulation of microtubule polymerization [inference]

positive regulation of microtubule nucleation

positive regulation of endocytosis

positive regulation of supramolecular fiber organization [inference]

positive regulation of microtubule polymerization [inference]

positive regulation of microtubule nucleation

positive regulation of transport [inference]

positive regulation of endocytosis

regulation of cellular process [inference]

regulation of cell communication [inference]

positive regulation of cell communication [inference]

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic plasticity [inference]

long-term synaptic potentiation

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

regulation of cellular metabolic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

mRNA localization resulting in post-transcriptional regulation of gene expression

regulation of microtubule-based process [inference]

regulation of microtubule cytoskeleton organization [inference]

regulation of microtubule polymerization or depolymerization [inference]

positive regulation of microtubule polymerization or depolymerization [inference]

positive regulation of microtubule polymerization [inference]

positive regulation of microtubule nucleation

regulation of microtubule polymerization [inference]

regulation of microtubule nucleation [inference]

positive regulation of microtubule nucleation

positive regulation of microtubule polymerization [inference]

positive regulation of microtubule nucleation

regulation of cellular component biogenesis [inference]

regulation of protein-containing complex assembly [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of protein polymerization [inference]

positive regulation of microtubule polymerization [inference]

positive regulation of microtubule nucleation

regulation of protein polymerization [inference]

regulation of microtubule polymerization [inference]

regulation of microtubule nucleation [inference]

positive regulation of microtubule nucleation

positive regulation of microtubule polymerization [inference]

positive regulation of microtubule nucleation

positive regulation of protein polymerization [inference]

positive regulation of microtubule polymerization [inference]

positive regulation of microtubule nucleation

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of protein polymerization [inference]

positive regulation of microtubule polymerization [inference]

positive regulation of microtubule nucleation

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of protein polymerization [inference]

positive regulation of microtubule polymerization [inference]

positive regulation of microtubule nucleation

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of cytoskeleton organization [inference]

positive regulation of microtubule polymerization or depolymerization [inference]

positive regulation of microtubule polymerization [inference]

positive regulation of microtubule nucleation

positive regulation of protein-containing complex assembly [inference]

positive regulation of protein polymerization [inference]

positive regulation of microtubule polymerization [inference]

positive regulation of microtubule nucleation

positive regulation of endocytosis

positive regulation of supramolecular fiber organization [inference]

positive regulation of microtubule polymerization [inference]

positive regulation of microtubule nucleation

regulation of cellular component organization [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis

regulation of organelle organization [inference]

positive regulation of organelle organization [inference]

positive regulation of cytoskeleton organization [inference]

positive regulation of microtubule polymerization or depolymerization [inference]

positive regulation of microtubule polymerization [inference]

positive regulation of microtubule nucleation

regulation of cytoskeleton organization [inference]

positive regulation of cytoskeleton organization [inference]

positive regulation of microtubule polymerization or depolymerization [inference]

positive regulation of microtubule polymerization [inference]

positive regulation of microtubule nucleation

regulation of microtubule cytoskeleton organization [inference]

regulation of microtubule polymerization or depolymerization [inference]

positive regulation of microtubule polymerization or depolymerization [inference]

positive regulation of microtubule polymerization [inference]

positive regulation of microtubule nucleation

regulation of microtubule polymerization [inference]

regulation of microtubule nucleation [inference]

positive regulation of microtubule nucleation

positive regulation of microtubule polymerization [inference]

positive regulation of microtubule nucleation

regulation of protein-containing complex assembly [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of protein polymerization [inference]

positive regulation of microtubule polymerization [inference]

positive regulation of microtubule nucleation

regulation of protein polymerization [inference]

regulation of microtubule polymerization [inference]

regulation of microtubule nucleation [inference]

positive regulation of microtubule nucleation

positive regulation of microtubule polymerization [inference]

positive regulation of microtubule nucleation

positive regulation of protein polymerization [inference]

positive regulation of microtubule polymerization [inference]

positive regulation of microtubule nucleation

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of cytoskeleton organization [inference]

positive regulation of microtubule polymerization or depolymerization [inference]

positive regulation of microtubule polymerization [inference]

positive regulation of microtubule nucleation

positive regulation of protein-containing complex assembly [inference]

positive regulation of protein polymerization [inference]

positive regulation of microtubule polymerization [inference]

positive regulation of microtubule nucleation

positive regulation of endocytosis

positive regulation of supramolecular fiber organization [inference]

positive regulation of microtubule polymerization [inference]

positive regulation of microtubule nucleation

regulation of supramolecular fiber organization [inference]

regulation of microtubule polymerization [inference]

regulation of microtubule nucleation [inference]

positive regulation of microtubule nucleation

positive regulation of microtubule polymerization [inference]

positive regulation of microtubule nucleation

positive regulation of supramolecular fiber organization [inference]

positive regulation of microtubule polymerization [inference]

positive regulation of microtubule nucleation

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis

regulation of biological quality [inference]

regulation of membrane potential [inference]

regulation of postsynaptic membrane potential [inference]

excitatory postsynaptic potential

regulation of synaptic plasticity [inference]

long-term synaptic potentiation

Displaying entries **1 - 5** of 20 in total

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GO Term	Evidence Code	PMID
kinetochore	ISO
kinetochore	IBA
kinetochore	IEA
spindle pole	ISO
spindle pole	IBA

GO Hierarchy

cellular component

protein-containing complex

cellular anatomical entity [inference]

microtubule organizing center [inference]

centrosome

membrane [inference]

plasma membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

dendrite

perikaryon

organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

microtubule cytoskeleton

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule [inference]

neuronal ribonucleoprotein granule

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

microtubule cytoskeleton

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule [inference]

neuronal ribonucleoprotein granule

postsynapse

supramolecular complex [inference]

kinetochore

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule [inference]

neuronal ribonucleoprotein granule

microtubule end [inference]

microtubule plus-end

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GO Term	Evidence Code	PMID
microtubule binding	ISO
microtubule binding	IBA
ribonucleoprotein complex binding	ISO
microtubule plus-end binding	IEA
microtubule plus end polymerase	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

microtubule plus end polymerase

catalytic activity, acting on a protein [inference]

microtubule plus end polymerase

binding [inference]

protein binding [inference]

cytoskeletal protein binding [inference]

tubulin binding [inference]

microtubule binding

microtubule plus-end binding

protein-containing complex binding [inference]

ribonucleoprotein complex binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

cytoskeleton-associated protein 5

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 6** entries
Gene Ontology
establishment or maintenance of microtubule cytoskeleton polarity
microtubule binding
microtubule plus end polymerase
microtubule plus-end binding
microtubule polymerization
tubulin binding

Displaying **all 5** entries
InterPro
Armadillo-like helical
Armadillo-type fold
TOG domain
XMAP215/Dis1/CLASP, TOG domain
XMAP215

Ortholog

Displaying entries **1 - 10** of 77 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	9793	Xenbase:XB-GENE-5871815	HUMAN05684
Xenopus tropicalis	75786	Xenbase:XB-GENE-5871815
Rattus norvegicus	311191		RATNO29086
Pan troglodytes	451160		PANTR02768
Canis lupus familiaris	475986		CANLF05859
Danio rerio	492614		DANRE27507
Bos taurus	533980		BOVIN07510
Macaca mulatta	714095		MACMU10143
Xenopus tropicalis	850734	Xenbase:XB-GENE-5871815
Monodelphis domestica	100011933		MONDO27889

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Last updated: April 7, 2025