GlyCosmos Portal

Annotation

Keyword

Alternative splicing
Endoplasmic reticulum
Glycoprotein
Hydrolase
Lipid metabolism
Mitochondrion
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q99LR1	2-arachidonoylglycerol hydrolase ABHD12 Abhydrolase domain-containing protein 12 Monoacylglycerol lipase ABHD12 Oxidized phosphatidylserine lipase ABHD12

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 16 in total

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GO Term	Evidence Code	PMID
protein depalmitoylation	IDA	27307232
phosphatidylserine catabolic process	ISO
phosphatidylserine catabolic process	IMP	23297193
phosphatidylserine catabolic process	IBA
adult walking behavior	IMP	23297193

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

cellular modified amino acid metabolic process [inference]

phosphatidylserine metabolic process [inference]

phosphatidylserine catabolic process

cellular modified amino acid catabolic process [inference]

phosphatidylserine catabolic process

protein metabolic process [inference]

protein catabolic process [inference]

lipoprotein catabolic process [inference]

protein depalmitoylation

protein modification process [inference]

protein deacylation [inference]

protein depalmitoylation

lipoprotein metabolic process [inference]

lipoprotein catabolic process [inference]

protein depalmitoylation

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

lipoprotein catabolic process [inference]

protein depalmitoylation

cellular modified amino acid catabolic process [inference]

phosphatidylserine catabolic process

catabolic process [inference]

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process

glycerophospholipid catabolic process

phosphatidylserine catabolic process

neutral lipid catabolic process [inference]

acylglycerol catabolic process

monoacylglycerol catabolic process

glycerolipid catabolic process [inference]

acylglycerol catabolic process

monoacylglycerol catabolic process

glycerophospholipid catabolic process

phosphatidylserine catabolic process

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

lipoprotein catabolic process [inference]

protein depalmitoylation

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process

glycerophospholipid catabolic process

phosphatidylserine catabolic process

neutral lipid catabolic process [inference]

acylglycerol catabolic process

monoacylglycerol catabolic process

glycerolipid catabolic process [inference]

acylglycerol catabolic process

monoacylglycerol catabolic process

glycerophospholipid catabolic process

phosphatidylserine catabolic process

organophosphate catabolic process [inference]

phospholipid catabolic process

glycerophospholipid catabolic process

phosphatidylserine catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

lipoprotein catabolic process [inference]

protein depalmitoylation

cellular modified amino acid catabolic process [inference]

phosphatidylserine catabolic process

cellular metabolic process [inference]

cellular modified amino acid metabolic process [inference]

phosphatidylserine metabolic process [inference]

phosphatidylserine catabolic process

cellular modified amino acid catabolic process [inference]

phosphatidylserine catabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process [inference]

phosphatidylserine catabolic process

glycerophospholipid catabolic process

phosphatidylserine catabolic process

phospholipid catabolic process

glycerophospholipid catabolic process

phosphatidylserine catabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process [inference]

phosphatidylserine catabolic process

glycerophospholipid catabolic process

phosphatidylserine catabolic process

phospholipid catabolic process

glycerophospholipid catabolic process

phosphatidylserine catabolic process

organophosphate catabolic process [inference]

phospholipid catabolic process

glycerophospholipid catabolic process

phosphatidylserine catabolic process

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process

glycerophospholipid catabolic process

phosphatidylserine catabolic process

neutral lipid catabolic process [inference]

acylglycerol catabolic process

monoacylglycerol catabolic process

glycerolipid catabolic process [inference]

acylglycerol catabolic process

monoacylglycerol catabolic process

glycerophospholipid catabolic process

phosphatidylserine catabolic process

cellular lipid metabolic process [inference]

neutral lipid metabolic process [inference]

acylglycerol metabolic process [inference]

monoacylglycerol metabolic process [inference]

monoacylglycerol catabolic process

acylglycerol catabolic process

monoacylglycerol catabolic process

neutral lipid catabolic process [inference]

acylglycerol catabolic process

monoacylglycerol catabolic process

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process [inference]

phosphatidylserine catabolic process

glycerophospholipid catabolic process

phosphatidylserine catabolic process

phospholipid catabolic process

glycerophospholipid catabolic process

phosphatidylserine catabolic process

cellular lipid catabolic process [inference]

phospholipid catabolic process

glycerophospholipid catabolic process

phosphatidylserine catabolic process

neutral lipid catabolic process [inference]

acylglycerol catabolic process

monoacylglycerol catabolic process

glycerolipid catabolic process [inference]

acylglycerol catabolic process

monoacylglycerol catabolic process

glycerophospholipid catabolic process

phosphatidylserine catabolic process

glycerolipid metabolic process [inference]

acylglycerol metabolic process [inference]

monoacylglycerol metabolic process [inference]

monoacylglycerol catabolic process

acylglycerol catabolic process

monoacylglycerol catabolic process

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process [inference]

phosphatidylserine catabolic process

glycerophospholipid catabolic process

phosphatidylserine catabolic process

glycerolipid catabolic process [inference]

acylglycerol catabolic process

monoacylglycerol catabolic process

glycerophospholipid catabolic process

phosphatidylserine catabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process

glycerophospholipid catabolic process

phosphatidylserine catabolic process

neutral lipid catabolic process [inference]

acylglycerol catabolic process

monoacylglycerol catabolic process

glycerolipid catabolic process [inference]

acylglycerol catabolic process

monoacylglycerol catabolic process

glycerophospholipid catabolic process

phosphatidylserine catabolic process

cellular lipid metabolic process [inference]

neutral lipid metabolic process [inference]

acylglycerol metabolic process [inference]

monoacylglycerol metabolic process [inference]

monoacylglycerol catabolic process

acylglycerol catabolic process

monoacylglycerol catabolic process

neutral lipid catabolic process [inference]

acylglycerol catabolic process

monoacylglycerol catabolic process

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process [inference]

phosphatidylserine catabolic process

glycerophospholipid catabolic process

phosphatidylserine catabolic process

phospholipid catabolic process

glycerophospholipid catabolic process

phosphatidylserine catabolic process

cellular lipid catabolic process [inference]

phospholipid catabolic process

glycerophospholipid catabolic process

phosphatidylserine catabolic process

neutral lipid catabolic process [inference]

acylglycerol catabolic process

monoacylglycerol catabolic process

glycerolipid catabolic process [inference]

acylglycerol catabolic process

monoacylglycerol catabolic process

glycerophospholipid catabolic process

phosphatidylserine catabolic process

glycerolipid metabolic process [inference]

acylglycerol metabolic process [inference]

monoacylglycerol metabolic process [inference]

monoacylglycerol catabolic process

acylglycerol catabolic process

monoacylglycerol catabolic process

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process [inference]

phosphatidylserine catabolic process

glycerophospholipid catabolic process

phosphatidylserine catabolic process

glycerolipid catabolic process [inference]

acylglycerol catabolic process

monoacylglycerol catabolic process

glycerophospholipid catabolic process

phosphatidylserine catabolic process

protein metabolic process [inference]

protein catabolic process [inference]

lipoprotein catabolic process [inference]

protein depalmitoylation

protein modification process [inference]

protein deacylation [inference]

protein depalmitoylation

lipoprotein metabolic process [inference]

lipoprotein catabolic process [inference]

protein depalmitoylation

organic substance metabolic process [inference]

lipid metabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process

glycerophospholipid catabolic process

phosphatidylserine catabolic process

neutral lipid catabolic process [inference]

acylglycerol catabolic process

monoacylglycerol catabolic process

glycerolipid catabolic process [inference]

acylglycerol catabolic process

monoacylglycerol catabolic process

glycerophospholipid catabolic process

phosphatidylserine catabolic process

cellular lipid metabolic process [inference]

neutral lipid metabolic process [inference]

acylglycerol metabolic process [inference]

monoacylglycerol metabolic process [inference]

monoacylglycerol catabolic process

acylglycerol catabolic process

monoacylglycerol catabolic process

neutral lipid catabolic process [inference]

acylglycerol catabolic process

monoacylglycerol catabolic process

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process [inference]

phosphatidylserine catabolic process

glycerophospholipid catabolic process

phosphatidylserine catabolic process

phospholipid catabolic process

glycerophospholipid catabolic process

phosphatidylserine catabolic process

cellular lipid catabolic process [inference]

phospholipid catabolic process

glycerophospholipid catabolic process

phosphatidylserine catabolic process

neutral lipid catabolic process [inference]

acylglycerol catabolic process

monoacylglycerol catabolic process

glycerolipid catabolic process [inference]

acylglycerol catabolic process

monoacylglycerol catabolic process

glycerophospholipid catabolic process

phosphatidylserine catabolic process

glycerolipid metabolic process [inference]

acylglycerol metabolic process [inference]

monoacylglycerol metabolic process [inference]

monoacylglycerol catabolic process

acylglycerol catabolic process

monoacylglycerol catabolic process

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process [inference]

phosphatidylserine catabolic process

glycerophospholipid catabolic process

phosphatidylserine catabolic process

glycerolipid catabolic process [inference]

acylglycerol catabolic process

monoacylglycerol catabolic process

glycerophospholipid catabolic process

phosphatidylserine catabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process [inference]

phosphatidylserine catabolic process

glycerophospholipid catabolic process

phosphatidylserine catabolic process

phospholipid catabolic process

glycerophospholipid catabolic process

phosphatidylserine catabolic process

organophosphate catabolic process [inference]

phospholipid catabolic process

glycerophospholipid catabolic process

phosphatidylserine catabolic process

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

lipoprotein catabolic process [inference]

protein depalmitoylation

protein metabolic process [inference]

protein catabolic process [inference]

lipoprotein catabolic process [inference]

protein depalmitoylation

protein modification process [inference]

protein deacylation [inference]

protein depalmitoylation

lipoprotein metabolic process [inference]

lipoprotein catabolic process [inference]

protein depalmitoylation

macromolecule modification [inference]

protein modification process [inference]

protein deacylation [inference]

protein depalmitoylation

macromolecule deacylation [inference]

protein deacylation [inference]

protein depalmitoylation

macromolecule depalmitoylation [inference]

protein depalmitoylation

organonitrogen compound metabolic process [inference]

cellular modified amino acid metabolic process [inference]

phosphatidylserine metabolic process [inference]

phosphatidylserine catabolic process

cellular modified amino acid catabolic process [inference]

phosphatidylserine catabolic process

protein metabolic process [inference]

protein catabolic process [inference]

lipoprotein catabolic process [inference]

protein depalmitoylation

protein modification process [inference]

protein deacylation [inference]

protein depalmitoylation

lipoprotein metabolic process [inference]

lipoprotein catabolic process [inference]

protein depalmitoylation

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

lipoprotein catabolic process [inference]

protein depalmitoylation

cellular modified amino acid catabolic process [inference]

phosphatidylserine catabolic process

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

lipoprotein catabolic process [inference]

protein depalmitoylation

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process

glycerophospholipid catabolic process

phosphatidylserine catabolic process

neutral lipid catabolic process [inference]

acylglycerol catabolic process

monoacylglycerol catabolic process

glycerolipid catabolic process [inference]

acylglycerol catabolic process

monoacylglycerol catabolic process

glycerophospholipid catabolic process

phosphatidylserine catabolic process

organophosphate catabolic process [inference]

phospholipid catabolic process

glycerophospholipid catabolic process

phosphatidylserine catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

lipoprotein catabolic process [inference]

protein depalmitoylation

cellular modified amino acid catabolic process [inference]

phosphatidylserine catabolic process

cellular process [inference]

cellular metabolic process [inference]

cellular modified amino acid metabolic process [inference]

phosphatidylserine metabolic process [inference]

phosphatidylserine catabolic process

cellular modified amino acid catabolic process [inference]

phosphatidylserine catabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process [inference]

phosphatidylserine catabolic process

glycerophospholipid catabolic process

phosphatidylserine catabolic process

phospholipid catabolic process

glycerophospholipid catabolic process

phosphatidylserine catabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process [inference]

phosphatidylserine catabolic process

glycerophospholipid catabolic process

phosphatidylserine catabolic process

phospholipid catabolic process

glycerophospholipid catabolic process

phosphatidylserine catabolic process

organophosphate catabolic process [inference]

phospholipid catabolic process

glycerophospholipid catabolic process

phosphatidylserine catabolic process

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process

glycerophospholipid catabolic process

phosphatidylserine catabolic process

neutral lipid catabolic process [inference]

acylglycerol catabolic process

monoacylglycerol catabolic process

glycerolipid catabolic process [inference]

acylglycerol catabolic process

monoacylglycerol catabolic process

glycerophospholipid catabolic process

phosphatidylserine catabolic process

cellular lipid metabolic process [inference]

neutral lipid metabolic process [inference]

acylglycerol metabolic process [inference]

monoacylglycerol metabolic process [inference]

monoacylglycerol catabolic process

acylglycerol catabolic process

monoacylglycerol catabolic process

neutral lipid catabolic process [inference]

acylglycerol catabolic process

monoacylglycerol catabolic process

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process [inference]

phosphatidylserine catabolic process

glycerophospholipid catabolic process

phosphatidylserine catabolic process

phospholipid catabolic process

glycerophospholipid catabolic process

phosphatidylserine catabolic process

cellular lipid catabolic process [inference]

phospholipid catabolic process

glycerophospholipid catabolic process

phosphatidylserine catabolic process

neutral lipid catabolic process [inference]

acylglycerol catabolic process

monoacylglycerol catabolic process

glycerolipid catabolic process [inference]

acylglycerol catabolic process

monoacylglycerol catabolic process

glycerophospholipid catabolic process

phosphatidylserine catabolic process

glycerolipid metabolic process [inference]

acylglycerol metabolic process [inference]

monoacylglycerol metabolic process [inference]

monoacylglycerol catabolic process

acylglycerol catabolic process

monoacylglycerol catabolic process

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process [inference]

phosphatidylserine catabolic process

glycerophospholipid catabolic process

phosphatidylserine catabolic process

glycerolipid catabolic process [inference]

acylglycerol catabolic process

monoacylglycerol catabolic process

glycerophospholipid catabolic process

phosphatidylserine catabolic process

multicellular organismal process [inference]

behavior [inference]

locomotory behavior [inference]

adult locomotory behavior [inference]

adult walking behavior

walking behavior [inference]

adult walking behavior

adult behavior [inference]

adult locomotory behavior [inference]

adult walking behavior

response to stimulus [inference]

response to external stimulus [inference]

response to mechanical stimulus [inference]

response to auditory stimulus

response to abiotic stimulus [inference]

response to mechanical stimulus [inference]

response to auditory stimulus

biological regulation [inference]

regulation of biological process [inference]

regulation of response to stimulus [inference]

regulation of response to external stimulus [inference]

regulation of inflammatory response

regulation of response to stress [inference]

regulation of defense response [inference]

regulation of inflammatory response

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GO Term	Evidence Code	PMID
cytoplasm	IDA	27307232
mitochondrion	IEA
endoplasmic reticulum membrane	ISO
endoplasmic reticulum membrane	IDA	30237167
endoplasmic reticulum membrane	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex [inference]

plasma membrane signaling receptor complex [inference]

neurotransmitter receptor complex [inference]

ionotropic glutamate receptor complex [inference]

AMPA glutamate receptor complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

plasma membrane signaling receptor complex [inference]

neurotransmitter receptor complex [inference]

ionotropic glutamate receptor complex [inference]

AMPA glutamate receptor complex

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

ionotropic glutamate receptor complex [inference]

AMPA glutamate receptor complex

transporter complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

ionotropic glutamate receptor complex [inference]

AMPA glutamate receptor complex

cellular anatomical entity [inference]

cytoplasm

cytoplasmic region [inference]

plasma membrane bounded cell projection cytoplasm [inference]

neuron projection cytoplasm [inference]

dendrite cytoplasm

membrane

organelle membrane [inference]

endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
phospholipase activity	ISO
lysophospholipase activity	ISO
lysophospholipase activity	IDA	30237167
lysophospholipase activity	IMP	25580854
lysophospholipase activity	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

lipase activity [inference]

phospholipase activity

lysophospholipase activity

acylglycerol lipase activity

thiolester hydrolase activity [inference]

palmitoyl-(protein) hydrolase activity

carboxylic ester hydrolase activity [inference]

palmitoyl hydrolase activity [inference]

palmitoyl-(protein) hydrolase activity

catalytic activity, acting on a protein [inference]

palmitoyl-(protein) hydrolase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Hydrolase

Functional Category

E: Amino acid transport and metabolism
I: Lipid transport and metabolism
T: Signal transduction mechanisms

Displaying 1 entry
InterPro
Alpha/Beta hydrolase fold

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0080181	PHARC syndrome	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 62 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	26090	Xenbase:XB-GENE-990130	HUMAN56366
Xenopus tropicalis	76192	Xenbase:XB-GENE-990130
Drosophila melanogaster	145447	FB:FBgn0034419
Canis lupus familiaris	477004		CANLF08903
Rattus norvegicus	499913	Xenbase:XB-GENE-990130	RATNO28975
Macaca mulatta	705915		MACMU02455
Pan troglodytes	744997		PANTR24541
Danio rerio	767657	Xenbase:XB-GENE-990130	DANRE12492
Bos taurus	768242		BOVIN04627
Monodelphis domestica	100033224		MONDO04379

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OrthoDB (Group)

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Acknowledgements