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Guidelines

MIRAGE

endoplasmic reticulum protein 44

Summary

Gene Symbol

Erp44

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

76299

PubChem

76299

Alliance of Genome Resources

MGI:1923549

Annotation

Keyword

Chaperone
Disulfide bond
Endoplasmic reticulum
Reference proteome
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9D1Q6	Thioredoxin domain-containing protein 4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
protein folding	ISS
protein folding	ISO
protein folding	IBA
response to unfolded protein	ISS
response to unfolded protein	ISO	11847130

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process

primary metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process

carbohydrate derivative metabolic process [inference]

glycoprotein metabolic process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process

cellular process [inference]

protein folding

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress

response to topologically incorrect protein [inference]

response to unfolded protein

response to chemical [inference]

response to organic substance [inference]

response to topologically incorrect protein [inference]

response to unfolded protein

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
endoplasmic reticulum lumen	ISS
endoplasmic reticulum lumen	ISO	11847130
endoplasmic reticulum membrane	ISS
endoplasmic reticulum membrane	ISO
endoplasmic reticulum membrane	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cell surface

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

endoplasmic reticulum lumen

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum-Golgi intermediate compartment

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum-Golgi intermediate compartment

Displaying **all 4** entries
GO Term	Evidence Code	PMID
protein disulfide isomerase activity	ISS
protein disulfide isomerase activity	ISO
protein disulfide isomerase activity	IBA
protein binding	IPI	15652484 23055941 23449976

GO Hierarchy

molecular function

catalytic activity [inference]

isomerase activity [inference]

intramolecular oxidoreductase activity [inference]

intramolecular oxidoreductase activity, transposing S-S bonds [inference]

protein disulfide isomerase activity

catalytic activity, acting on a protein [inference]

protein disulfide isomerase activity

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Endoplasmic reticulum resident protein 44

Functional Category

C: Energy production and conversion
E: Amino acid transport and metabolism
M: Cell wall/membrane/envelope biogenesis

Displaying **all 3** entries
InterPro
Endoplasmic reticulum resident protein 44, TRX-like domain b'
Thioredoxin domain
Thioredoxin-like superfamily

Ortholog

Displaying entries **1 - 10** of 73 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	23071	Xenbase:XB-GENE-962188	HUMAN97820
Xenopus tropicalis	76299	Xenbase:XB-GENE-962188
Xenopus tropicalis	177572	Xenbase:XB-GENE-962188
Rattus norvegicus	298066		RATNO34311
Danio rerio	393866		DANRE11297
Pan troglodytes	464616		PANTR44468
Bos taurus	506157		BOVIN34659
Monodelphis domestica	100011005		MONDO29178
Ornithorhynchus anatinus	100075491		ORNAN30926
Sus scrofa	100192437		PIGXX15807

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Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.4.0

Last updated: December 8, 2025