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SEC24 homolog A, COPII coat complex component

Summary

Gene Symbol

Sec24a

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

77371

PubChem

77371

Alliance of Genome Resources

MGI:1924621

Annotation

Keyword

Alternative splicing
Cytoplasm
Cytoplasmic vesicle
ER-Golgi transport
Endoplasmic reticulum
Membrane
Metal-binding
Protein transport
Proteomics identification
Reference proteome
Zinc

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A2AA71
Q3U2P1	SEC24-related protein A

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
intracellular protein transport	IEA
endoplasmic reticulum to Golgi vesicle-mediated transport	ISS
endoplasmic reticulum to Golgi vesicle-mediated transport	ISO
regulation of cholesterol transport	IMP	23580231
cholesterol homeostasis	IMP	23580231

GO Hierarchy

biological process

cellular process [inference]

vesicle-mediated transport [inference]

Golgi vesicle transport [inference]

endoplasmic reticulum to Golgi vesicle-mediated transport

cellular localization [inference]

intracellular transport [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport

homeostatic process [inference]

chemical homeostasis [inference]

lipid homeostasis [inference]

sterol homeostasis [inference]

cholesterol homeostasis

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

Golgi vesicle transport [inference]

endoplasmic reticulum to Golgi vesicle-mediated transport

vesicle cargo loading [inference]

COPII-coated vesicle cargo loading

intracellular transport [inference]

organic substance transport [inference]

protein transport [inference]

intracellular protein transport

nitrogen compound transport [inference]

protein transport [inference]

intracellular protein transport

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport

establishment of localization in cell [inference]

intracellular transport [inference]

cellular localization [inference]

intracellular transport [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of lipid transport [inference]

regulation of sterol transport [inference]

regulation of cholesterol transport

regulation of secretion [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

regulation of secretion by cell [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

positive regulation of transport [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion

regulation of protein transport [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

regulation of lipid localization [inference]

regulation of lipid transport [inference]

regulation of sterol transport [inference]

regulation of cholesterol transport

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of transport [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion

regulation of cellular process [inference]

positive regulation of cellular process [inference]

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

regulation of secretion by cell [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
endoplasmic reticulum membrane	IEA
cytosol	IEA
COPII vesicle coat	ISS
COPII vesicle coat	ISO
COPII vesicle coat	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

membrane coat [inference]

vesicle coat [inference]

COPII vesicle coat

cellular anatomical entity [inference]

cytosol

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

endoplasmic reticulum exit site

Displaying **all 4** entries
GO Term	Evidence Code	PMID
SNARE binding	IBA
zinc ion binding	ISO
zinc ion binding	IBA
zinc ion binding	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

SNARE binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

protein transport protein Sec24A

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
COPII-coated vesicle cargo loading
SNARE binding
zinc ion binding

Displaying **all 10** entries
InterPro
ADF-H/Gelsolin-like domain superfamily
Gelsolin-like domain superfamily
Gelsolin-like domain
Sec23/Sec24 beta-sandwich
Sec23/Sec24 helical domain superfamily
Sec23/Sec24, helical domain
Sec23/Sec24, trunk domain
Sec24-like, trunk domain
Zinc finger, Sec23/Sec24-type
von Willebrand factor A-like domain superfamily

Ortholog

Displaying entries **1 - 10** of 83 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Saccharomyces cerevisiae S288C	10427	SGD:S000001371
Homo sapiens	10802	Xenbase:XB-GENE-987688	HUMAN80818
Xenopus tropicalis	77371	Xenbase:XB-GENE-987688
Saccharomyces cerevisiae S288C	99683	SGD:S000001371
Rattus norvegicus	287275		RATNO02830
Pan troglodytes	471787		PANTR36188
Canis lupus familiaris	481510		CANLF02116
Bos taurus	505089		BOVIN33456
Macaca mulatta	711109		MACMU39030
Danio rerio	100000526		DANRE21956