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SEC24 homolog A, COPII coat complex component

Summary

Gene Symbol

Sec24a

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

77371

PubChem

77371

Alliance of Genome Resources

MGI:1924621

Annotation

Keyword

Alternative splicing
Cytoplasm
Cytoplasmic vesicle
ER-Golgi transport
Endoplasmic reticulum
Membrane
Metal-binding
Protein transport
Proteomics identification
Reference proteome
Zinc

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A2AA71
Q3U2P1	SEC24-related protein A

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 9** of 9 in total

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GO Term	Evidence Code	PMID
positive regulation of protein secretion	IMP	23580231
COPII-coated vesicle cargo loading	ISS
COPII-coated vesicle cargo loading	ISO
COPII-coated vesicle cargo loading	IBA

GO Hierarchy

biological process

cellular process [inference]

vesicle-mediated transport [inference]

Golgi vesicle transport [inference]

endoplasmic reticulum to Golgi vesicle-mediated transport

cellular localization [inference]

intracellular transport [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport

homeostatic process [inference]

chemical homeostasis [inference]

lipid homeostasis [inference]

sterol homeostasis [inference]

cholesterol homeostasis

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

Golgi vesicle transport [inference]

endoplasmic reticulum to Golgi vesicle-mediated transport

vesicle cargo loading [inference]

COPII-coated vesicle cargo loading

intracellular transport [inference]

organic substance transport [inference]

protein transport [inference]

intracellular protein transport

nitrogen compound transport [inference]

protein transport [inference]

intracellular protein transport

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport

establishment of localization in cell [inference]

intracellular transport [inference]

cellular localization [inference]

intracellular transport [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of lipid transport [inference]

regulation of sterol transport [inference]

regulation of cholesterol transport

regulation of secretion [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

regulation of secretion by cell [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

positive regulation of transport [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion

regulation of protein transport [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

regulation of lipid localization [inference]

regulation of lipid transport [inference]

regulation of sterol transport [inference]

regulation of cholesterol transport

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of transport [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion

regulation of cellular process [inference]

positive regulation of cellular process [inference]

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

regulation of secretion by cell [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

Displaying entry **6 - 6** of 6 in total

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GO Term	Evidence Code	PMID
endoplasmic reticulum exit site	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

membrane coat [inference]

vesicle coat [inference]

COPII vesicle coat

cellular anatomical entity [inference]

cytosol

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

endoplasmic reticulum exit site

Displaying **all 4** entries
GO Term	Evidence Code	PMID
SNARE binding	IBA
zinc ion binding	ISO
zinc ion binding	IBA
zinc ion binding	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

SNARE binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

SEC24

Functional Category

E: Amino acid transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
COPII-coated vesicle cargo loading
SNARE binding
zinc ion binding

Displaying **all 10** entries
InterPro
ADF-H/Gelsolin-like domain superfamily
Gelsolin-like domain superfamily
Gelsolin-like domain
Sec23/Sec24 beta-sandwich
Sec23/Sec24 helical domain superfamily
Sec23/Sec24, helical domain
Sec23/Sec24, trunk domain
Zinc finger, Sec23/Sec24-type superfamily
Zinc finger, Sec23/Sec24-type
von Willebrand factor A-like domain superfamily

Ortholog

Displaying entries **31 - 40** of 83 in total

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Species	Gene ID	Orthologous MAtrix
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Octodon degus	101564941	OCTDE07167
Mustela putorius furo	101672078	MUSPF16780
Ficedula albicollis	101815149	FICAL11390
Melopsittacus undulatus	101875659	MELUD09801
Chrysemys picta bellii	101933567	CHRPI36437
Ictidomys tridecemlineatus	101964136	ICTTR17586
Chinchilla lanigera	102017201	CHILA02165
Capra hircus	102176523	CAPHI27454