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myosin, heavy polypeptide 10, non-muscle

Summary

Gene Symbol

Myh10

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

77579

PubChem

77579

Alliance of Genome Resources

MGI:1930780

Annotation

Keyword

ATP-binding
Acetylation
Actin-binding
Calmodulin-binding
Cell adhesion
Cell projection
Cell shape
Coiled coil
Methylation
Myosin
Phosphoprotein
Proteomics identification
Reference proteome

Proteins

Displaying **all 3** entries
UniProt	Protein Name
Q3UH59	Cellular myosin heavy chain, type B Myosin heavy chain 10 Myosin heavy chain, non-muscle IIb Non-muscle myosin heavy chain B Non-muscle myosin heavy chain IIb
Q61879	Cellular myosin heavy chain, type B Myosin heavy chain 10 Myosin heavy chain, non-muscle IIb Non-muscle myosin heavy chain B Non-muscle myosin heavy chain IIb
Q5SV64	Cellular myosin heavy chain, type B Myosin heavy chain 10 Myosin heavy chain, non-muscle IIb Non-muscle myosin heavy chain B Non-muscle myosin heavy chain IIb

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 43 in total

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GO Term	Evidence Code	PMID
mitotic cytokinesis	ISO
mitotic cytokinesis	IMP	12893741
mitotic cytokinesis	IBA
in utero embryonic development	IMP	11283949 12893741 9356462
neuron migration	IMP	10712438 11283949 15034141 16481398

GO Hierarchy

biological process

cellular process [inference]

cell adhesion

cell population proliferation [inference]

muscle cell proliferation [inference]

striated muscle cell proliferation [inference]

cardiac muscle cell proliferation

vesicle-mediated transport [inference]

exocytosis

cell cycle process [inference]

cytokinesis [inference]

cytoskeleton-dependent cytokinesis [inference]

mitotic cytokinesis

mitotic cell cycle process [inference]

mitotic cytokinesis

actin filament-based process [inference]

actin cytoskeleton organization

actomyosin structure organization

myofibril assembly

cardiac myofibril assembly

postsynaptic actin cytoskeleton organization

actin filament-based movement

cellular developmental process [inference]

cell development [inference]

muscle cell development [inference]

cardiac muscle cell development [inference]

ventricular cardiac muscle cell development

cardiac cell development [inference]

cardiac muscle cell development [inference]

ventricular cardiac muscle cell development

cell motility [inference]

cell migration [inference]

neuron migration

cellular localization [inference]

intracellular transport [inference]

nuclear migration

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

actin cytoskeleton organization

actomyosin structure organization

myofibril assembly

cardiac myofibril assembly

postsynaptic actin cytoskeleton organization

postsynaptic cytoskeleton organization [inference]

postsynaptic actin cytoskeleton organization

organelle assembly [inference]

non-membrane-bounded organelle assembly [inference]

myofibril assembly

cardiac myofibril assembly

cellular component assembly [inference]

cellular component assembly involved in morphogenesis [inference]

myofibril assembly

cardiac myofibril assembly

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

substrate-dependent cell migration, cell extension

actin filament bundle assembly

organelle assembly [inference]

non-membrane-bounded organelle assembly [inference]

myofibril assembly

cardiac myofibril assembly

cell projection organization [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

substrate-dependent cell migration, cell extension

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis [inference]

axonogenesis

plasma membrane bounded cell projection organization [inference]

neuron projection development

neuron projection guidance [inference]

axon guidance

plasma membrane bounded cell projection assembly [inference]

substrate-dependent cell migration, cell extension

cell junction organization [inference]

synapse organization [inference]

modification of synaptic structure [inference]

modification of postsynaptic structure [inference]

modification of postsynaptic actin cytoskeleton

membrane organization [inference]

plasma membrane organization [inference]

plasma membrane repair

supramolecular fiber organization [inference]

actin filament organization [inference]

actin filament bundle organization [inference]

myofibril assembly

cardiac myofibril assembly

export from cell [inference]

secretion by cell [inference]

exocytosis

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

neuromuscular process [inference]

neuromuscular process controlling balance

multicellular organism development [inference]

embryo development [inference]

embryo development ending in birth or egg hatching [inference]

chordate embryonic development [inference]

in utero embryonic development

developmental process [inference]

anatomical structure morphogenesis [inference]

cellular anatomical entity morphogenesis [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis [inference]

axonogenesis

anatomical structure formation involved in morphogenesis [inference]

cellular component assembly involved in morphogenesis [inference]

myofibril assembly

cardiac myofibril assembly

anatomical structure development [inference]

blood vessel development [inference]

artery development [inference]

aorta development

coronary vasculature development

cardiac septum development

multicellular organism development [inference]

embryo development [inference]

embryo development ending in birth or egg hatching [inference]

chordate embryonic development [inference]

in utero embryonic development

cell development [inference]

muscle cell development [inference]

cardiac muscle cell development [inference]

ventricular cardiac muscle cell development

cardiac cell development [inference]

cardiac muscle cell development [inference]

ventricular cardiac muscle cell development

animal organ development [inference]

brain development

heart development

adult heart development

retina development in camera-type eye

cellular developmental process [inference]

cell development [inference]

muscle cell development [inference]

cardiac muscle cell development [inference]

ventricular cardiac muscle cell development

cardiac cell development [inference]

cardiac muscle cell development [inference]

ventricular cardiac muscle cell development

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

exocytosis

secretion [inference]

secretion by cell [inference]

exocytosis

intracellular transport [inference]

nuclear migration

export from cell [inference]

secretion by cell [inference]

exocytosis

establishment of localization in cell [inference]

intracellular transport [inference]

nuclear migration

establishment of organelle localization [inference]

nuclear migration

organelle localization [inference]

nucleus localization [inference]

nuclear migration

establishment of organelle localization [inference]

nuclear migration

cellular localization [inference]

intracellular transport [inference]

nuclear migration

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of secretion [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

regulation of secretion by cell [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

positive regulation of transport [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion

regulation of protein transport [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of transport [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of cell morphogenesis [inference]

regulation of cell shape

regulation of cellular process [inference]

positive regulation of cellular process [inference]

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

regulation of cellular component organization [inference]

regulation of synapse organization [inference]

regulation of modification of synaptic structure [inference]

regulation of modification of postsynaptic structure [inference]

regulation of modification of postsynaptic actin cytoskeleton

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

regulation of secretion by cell [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

regulation of biological quality [inference]

regulation of cell shape

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GO Term	Evidence Code	PMID
stress fiber	ISO
stress fiber	IDA	12893741 14699073
stress fiber	IMP	14617807
cytoplasm	ISO
cytoplasm	IDA	12724421 15177565 16895968 8482409 9725909

GO Hierarchy

cellular component

protein-containing complex [inference]

myosin complex

myosin II complex

cellular anatomical entity [inference]

cytoplasm

cytosol

membrane [inference]

plasma membrane region [inference]

cleavage furrow

cell junction [inference]

synapse [inference]

site of polarized growth [inference]

growth cone

midbody

actin filament bundle [inference]

contractile actin filament bundle [inference]

stress fiber

actomyosin

stress fiber

cell projection [inference]

plasma membrane bounded cell projection [inference]

lamellipodium

neuron projection

axon

neuron spine [inference]

dendritic spine

organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

spindle

cytoskeleton [inference]

actin cytoskeleton [inference]

postsynaptic actin cytoskeleton

postsynaptic cytoskeleton [inference]

postsynaptic actin cytoskeleton

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

spindle

cytoskeleton [inference]

actin cytoskeleton [inference]

postsynaptic actin cytoskeleton

postsynaptic cytoskeleton [inference]

postsynaptic actin cytoskeleton

cell body [inference]

neuronal cell body

side of membrane [inference]

cytoplasmic side of membrane [inference]

cytoplasmic side of plasma membrane

postsynapse [inference]

dendritic spine

cluster of actin-based cell projections [inference]

brush border

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

myosin filament

myosin II filament

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
microfilament motor activity	ISO
microfilament motor activity	IBA
protein binding	IPI	12724421 15663482 20439720 20850431
calmodulin binding	IEA
ATP binding	ISO

GO Hierarchy

molecular function

cytoskeletal motor activity [inference]

microfilament motor activity

binding [inference]

protein binding

calmodulin binding

cytoskeletal protein binding [inference]

actin binding [inference]

actin filament binding

identical protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

ADP binding

protein-containing complex binding [inference]

actin filament binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding [inference]

mRNA binding [inference]

mRNA 5'-UTR binding

RNA stem-loop binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP-dependent activity [inference]

microfilament motor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

myosin

Functional Category

G: Carbohydrate transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
ATP binding
actin binding
actin filament binding
cytoskeletal motor activity
nucleotide binding

Displaying **all 7** entries
InterPro
IQ motif, EF-hand binding site
Kinesin motor domain superfamily
Myosin S1 fragment, N-terminal
Myosin head, motor domain
Myosin tail
Myosin, N-terminal, SH3-like
P-loop containing nucleoside triphosphate hydrolase

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements