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notum palmitoleoyl-protein carboxylesterase

Summary

Gene Symbol

Notum

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

77583

PubChem

77583

Alliance of Genome Resources

MGI:1924833

Annotation

Keyword

Alternative splicing
Glycoprotein
Phosphoprotein
Reference proteome
Secreted
Serine esterase
Signal
Wnt signaling pathway

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8R116

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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2

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GO Term	Evidence Code	PMID
negative regulation of canonical Wnt signaling pathway	IBA IDA	30622831
bone development	IMP ISO	30622831
regulation of bone mineralization	IDA IMP ISO	30622831
protein depalmitoleylation	ISO ISS
Wnt signaling pathway	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein catabolic process [inference]

lipoprotein catabolic process [inference]

protein depalmitoleylation

protein modification process [inference]

protein deacylation [inference]

protein depalmitoleylation

lipoprotein metabolic process [inference]

lipoprotein catabolic process [inference]

protein depalmitoleylation

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

lipoprotein catabolic process [inference]

protein depalmitoleylation

catabolic process [inference]

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

lipoprotein catabolic process [inference]

protein depalmitoleylation

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

lipoprotein catabolic process [inference]

protein depalmitoleylation

primary metabolic process [inference]

protein metabolic process [inference]

protein catabolic process [inference]

lipoprotein catabolic process [inference]

protein depalmitoleylation

protein modification process [inference]

protein deacylation [inference]

protein depalmitoleylation

lipoprotein metabolic process [inference]

lipoprotein catabolic process [inference]

protein depalmitoleylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

lipoprotein catabolic process [inference]

protein depalmitoleylation

protein metabolic process [inference]

protein catabolic process [inference]

lipoprotein catabolic process [inference]

protein depalmitoleylation

protein modification process [inference]

protein deacylation [inference]

protein depalmitoleylation

lipoprotein metabolic process [inference]

lipoprotein catabolic process [inference]

protein depalmitoleylation

macromolecule modification [inference]

protein modification process [inference]

protein deacylation [inference]

protein depalmitoleylation

macromolecule deacylation [inference]

protein deacylation [inference]

protein depalmitoleylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein catabolic process [inference]

lipoprotein catabolic process [inference]

protein depalmitoleylation

protein modification process [inference]

protein deacylation [inference]

protein depalmitoleylation

lipoprotein metabolic process [inference]

lipoprotein catabolic process [inference]

protein depalmitoleylation

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

lipoprotein catabolic process [inference]

protein depalmitoleylation

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

lipoprotein catabolic process [inference]

protein depalmitoleylation

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

lipoprotein catabolic process [inference]

protein depalmitoleylation

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Wnt signaling pathway

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

bone development

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway

negative regulation of canonical Wnt signaling pathway

regulation of Wnt signaling pathway [inference]

negative regulation of Wnt signaling pathway

negative regulation of canonical Wnt signaling pathway

regulation of canonical Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway

negative regulation of canonical Wnt signaling pathway

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway

negative regulation of canonical Wnt signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway

negative regulation of canonical Wnt signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway

negative regulation of canonical Wnt signaling pathway

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway

negative regulation of canonical Wnt signaling pathway

regulation of Wnt signaling pathway [inference]

negative regulation of Wnt signaling pathway

negative regulation of canonical Wnt signaling pathway

regulation of canonical Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway

negative regulation of canonical Wnt signaling pathway

regulation of developmental process [inference]

regulation of multicellular organismal development [inference]

regulation of biomineral tissue development [inference]

regulation of bone mineralization

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Wnt signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway

negative regulation of canonical Wnt signaling pathway

regulation of Wnt signaling pathway [inference]

negative regulation of Wnt signaling pathway

negative regulation of canonical Wnt signaling pathway

regulation of canonical Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway

negative regulation of canonical Wnt signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway

negative regulation of canonical Wnt signaling pathway

regulation of multicellular organismal process [inference]

regulation of ossification [inference]

regulation of bone mineralization

regulation of multicellular organismal development [inference]

regulation of biomineral tissue development [inference]

regulation of bone mineralization

Displaying **all 2** entries
GO Term	Evidence Code	PMID
extracellular region	IEA
cellular_component	ND

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular region

Displaying **all 3** entries
GO Term	Evidence Code	PMID
lipase activity	IDA	30622831
protein-containing complex destabilizing activity	IDA	25771893
palmitoleyl hydrolase activity	IBA IDA ISO ISS	25771893

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

lipase activity

carboxylic ester hydrolase activity [inference]

palmitoleyl hydrolase activity

protein-containing complex destabilizing activity

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying entries **61 - 64** of 64 in total

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Species	Gene ID	Orthologous MAtrix
Scophthalmus maximus	118289330	SCOMX14070
Balaenoptera musculus	118886838	BALMU10216
Panthera leo	122206259	PANLE04746
Ursus americanus	123777950	URSAM26423

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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