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adhesion G protein-coupled receptor L1

Summary

Gene Symbol

ADGRL1

Organism

Bos taurus (domestic cattle)

External Links

NCBI Gene: 788252
PubChem: 788252

Annotation

Keyword

Alternative splicing
Cell membrane
Cell projection
Disulfide bond
G-protein coupled receptor
Glycoprotein
Lectin
Methylation
Phosphoprotein
Reference proteome
Signal
Synaptosome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
O97831	Calcium-independent alpha-latrotoxin receptor 1 Latrophilin-1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	IEA	30032202
signal transduction
cell surface receptor signaling pathway	IEA	22301074
adenylate cyclase-activating G protein-coupled receptor signaling pathway	IEA	30032202

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion [inference]

cell-cell adhesion via plasma-membrane adhesion molecules [inference]

heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules

signal transduction

cell surface receptor signaling pathway

G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction

cell surface receptor signaling pathway

G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
extracellular space
plasma membrane	IEA	30032202
axon	IEA	30032202
growth cone
presynaptic membrane	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular space

membrane [inference]

plasma membrane

plasma membrane region [inference]

synaptic membrane [inference]

presynaptic membrane

cell junction [inference]

synapse

site of polarized growth [inference]

growth cone

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection

axon

Displaying **all 4** entries
GO Term	Evidence Code	PMID
G protein-coupled receptor activity	IEA	22301074 30032202
latrotoxin receptor activity	IEA	30032202
carbohydrate binding	IEA	22301074
cell adhesion molecule binding

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

cell adhesion molecule binding

carbohydrate binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

adhesion G protein-coupled receptor L2

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying 1 entry
Gene Ontology
cell surface receptor signaling pathway

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InterPro
D-galactoside/L-rhamnose binding SUEL lectin domain superfamily
D-galactoside/L-rhamnose binding SUEL lectin domain
GAIN domain superfamily
GAIN domain, N-terminal
GPCR family 2, extracellular hormone receptor domain superfamily
GPCR, family 2, extracellular hormone receptor domain
GPCR, family 2, latrophilin, C-terminal
GPCR, family 2, latrophilin
GPCR, family 2, secretin-like, conserved site
GPCR, family 2, secretin-like

Ortholog

Displaying entries **1 - 10** of 68 in total

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Species	Gene ID	Orthologous MAtrix
Homo sapiens	22859	HUMAN41359
Rattus norvegicus	65096	RATNO14647
Mus musculus	330814	MOUSE58038
Pan troglodytes	455777	PANTR17396
Danio rerio	562531	DANRE32318
Canis lupus familiaris	610349	CANLF07770
Macaca mulatta	718708	MACMU19270
Monodelphis domestica	100026806	MONDO20040
Ornithorhynchus anatinus	100088198	ORNAN24965
Callithrix jacchus	100396023	CALJA24037