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MIRAGE
FTO alpha-ketoglutarate dependent dioxygenase

Summary
Gene Symbol
  • FTO
Organism
Homo sapiens (human)
NCBI Gene
79068
PubChem
79068
Alliance of Genome Resources
JoGo
FTO
TogoVar
FTO
Annotation
Keyword
  • 3D-structure
  • Acetylation
  • Alternative splicing
  • Cytoplasm
  • Dioxygenase
  • Disease variant
  • Iron
  • Metal-binding
  • Nucleus
  • Obesity
  • Phosphoprotein
  • Proteomics identification
  • Reference proteome
  • Transferase
Proteins
Displaying all 4 entries
UniProt Protein Name
Q9C0B1
  • Fat mass and obesity-associated protein
  • U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTO
  • U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO
  • mRNA (2'-O-methyladenosine-N(6)-)-demethylase FTO
  • mRNA N(6)-methyladenosine demethylase FTO
  • tRNA N1-methyl adenine demethylase FTO
A0A1B0GTC5
  • Fat mass and obesity-associated protein
  • U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTO
  • U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO
  • mRNA (2'-O-methyladenosine-N(6)-)-demethylase FTO
  • mRNA N(6)-methyladenosine demethylase FTO
  • tRNA N1-methyl adenine demethylase FTO
B3KU60
  • Fat mass and obesity-associated protein
  • U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTO
  • U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO
  • mRNA (2'-O-methyladenosine-N(6)-)-demethylase FTO
  • mRNA N(6)-methyladenosine demethylase FTO
  • tRNA N1-methyl adenine demethylase FTO
Q99770
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entry 11 - 11 of 11 in total
GO Term Evidence Code PMID
regulation of brown fat cell differentiation
GO Hierarchy
Displaying entries 1 - 5 of 11 in total
GO Term Evidence Code PMID
protein binding
ferrous iron binding
ferrous iron binding
transferase activity
oxidative RNA demethylase activity
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
Disease
Disease Ontology
Displaying entries 1 - 10 of 13 in total
DO ID Disease Name Source
DOID:0080334 aortic valve disease 2
DOID:10763 hypertension
DOID:10825 essential hypertension
DOID:1287 cardiovascular system disease
DOID:13963 nuclear senile cataract
DOID:3393 coronary artery disease
DOID:4450 renal cell carcinoma
DOID:4467 clear cell renal cell carcinoma
DOID:5844 myocardial infarction
DOID:9352 type 2 diabetes mellitus
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026