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Guidelines

MIRAGE

ribonuclease T2

Summary

Gene Symbol

rnaset2

Organism

Danio rerio (zebrafish)

External Links

NCBI Gene

791890

PubChem

791890

Alliance of Genome Resources

ZFIN:ZDB-GENE-030131-2513

Annotation

Keyword

Disulfide bond
Endonuclease
Endoplasmic reticulum
Glycoprotein
Lyase
Lysosome
Proteomics identification
Reference proteome
Secreted
Signal

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A8M9PY62
B8XY56	RNase Dre2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
RNA catabolic process	IBA
rRNA catabolic process	IMP	21199949

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

ncRNA catabolic process [inference]

rRNA catabolic process

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA catabolic process

ncRNA catabolic process [inference]

rRNA catabolic process

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA catabolic process

ncRNA catabolic process [inference]

rRNA catabolic process

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

ncRNA catabolic process [inference]

rRNA catabolic process

catabolic process [inference]

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

ncRNA catabolic process [inference]

rRNA catabolic process

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

ncRNA catabolic process [inference]

rRNA catabolic process

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

ncRNA catabolic process [inference]

rRNA catabolic process

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

RNA catabolic process

ncRNA catabolic process [inference]

rRNA catabolic process

organic cyclic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

ncRNA catabolic process [inference]

rRNA catabolic process

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

ncRNA catabolic process [inference]

rRNA catabolic process

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA catabolic process

ncRNA catabolic process [inference]

rRNA catabolic process

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA catabolic process

ncRNA catabolic process [inference]

rRNA catabolic process

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

ncRNA catabolic process [inference]

rRNA catabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

ncRNA catabolic process [inference]

rRNA catabolic process

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA catabolic process

ncRNA catabolic process [inference]

rRNA catabolic process

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA catabolic process

ncRNA catabolic process [inference]

rRNA catabolic process

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

ncRNA catabolic process [inference]

rRNA catabolic process

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

ncRNA catabolic process [inference]

rRNA catabolic process

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

ncRNA catabolic process [inference]

rRNA catabolic process

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

ncRNA catabolic process [inference]

rRNA catabolic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

ncRNA catabolic process [inference]

rRNA catabolic process

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA catabolic process

ncRNA catabolic process [inference]

rRNA catabolic process

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA catabolic process

ncRNA catabolic process [inference]

rRNA catabolic process

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

ncRNA catabolic process [inference]

rRNA catabolic process

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

ncRNA catabolic process [inference]

rRNA catabolic process

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA catabolic process

ncRNA catabolic process [inference]

rRNA catabolic process

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA catabolic process

ncRNA catabolic process [inference]

rRNA catabolic process

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

RNA catabolic process

ncRNA catabolic process [inference]

rRNA catabolic process

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA catabolic process

ncRNA catabolic process [inference]

rRNA catabolic process

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA catabolic process

ncRNA catabolic process [inference]

rRNA catabolic process

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

ncRNA catabolic process [inference]

rRNA catabolic process

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA catabolic process

ncRNA catabolic process [inference]

rRNA catabolic process

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA catabolic process

ncRNA catabolic process [inference]

rRNA catabolic process

organic cyclic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

ncRNA catabolic process [inference]

rRNA catabolic process

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

RNA catabolic process

ncRNA catabolic process [inference]

rRNA catabolic process

organic cyclic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

ncRNA catabolic process [inference]

rRNA catabolic process

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

ncRNA catabolic process [inference]

rRNA catabolic process

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA catabolic process

ncRNA catabolic process [inference]

rRNA catabolic process

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA catabolic process

ncRNA catabolic process [inference]

rRNA catabolic process

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

ncRNA catabolic process [inference]

rRNA catabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

ncRNA catabolic process [inference]

rRNA catabolic process

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA catabolic process

ncRNA catabolic process [inference]

rRNA catabolic process

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA catabolic process

ncRNA catabolic process [inference]

rRNA catabolic process

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

ncRNA catabolic process [inference]

rRNA catabolic process

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

ncRNA catabolic process [inference]

rRNA catabolic process

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

ncRNA catabolic process [inference]

rRNA catabolic process

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

ncRNA catabolic process [inference]

rRNA catabolic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

ncRNA catabolic process [inference]

rRNA catabolic process

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA catabolic process

ncRNA catabolic process [inference]

rRNA catabolic process

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA catabolic process

ncRNA catabolic process [inference]

rRNA catabolic process

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

ncRNA catabolic process [inference]

rRNA catabolic process

Displaying entries **1 - 5** of 6 in total

1

2

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GO Term	Evidence Code	PMID
extracellular region	IBA
extracellular region	IEA
lysosome	IEA
endoplasmic reticulum	IEA
endoplasmic reticulum lumen	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular region

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

vacuolar lumen [inference]

lysosomal lumen

endoplasmic reticulum lumen

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

endoplasmic reticulum

Displaying entries **1 - 5** of 7 in total

1

2

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GO Term	Evidence Code	PMID
RNA binding	IEA
nuclease activity	IEA
endonuclease activity	IEA
RNA endonuclease activity	IBA
hydrolase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity

hydrolase activity, acting on ester bonds [inference]

nuclease activity

endonuclease activity

RNA endonuclease activity

ribonuclease T2 activity

RNA nuclease activity [inference]

RNA endonuclease activity

ribonuclease T2 activity

phosphorus-oxygen lyase activity [inference]

ribonuclease T2 activity

catalytic activity, acting on a nucleic acid [inference]

catalytic activity, acting on RNA [inference]

RNA nuclease activity [inference]

RNA endonuclease activity

ribonuclease T2 activity

binding [inference]

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

ribonuclease T

Functional Category

J: Translation, ribosomal structure and biogenesis
K: Transcription
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
RNA catabolic process
RNA endonuclease activity
ribonuclease T2 activity

Displaying **all 5** entries
InterPro
Ribonuclease T2, His active site 1
Ribonuclease T2, His active site 2
Ribonuclease T2, eukaryotic
Ribonuclease T2-like superfamily
Ribonuclease T2-like

Alliance of Genome Resources

Expression

Displaying 1 entry
Location	References
cell pole	PMID:19619322

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0081007	RNASET2-deficient cystic leukoencephalopathy	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 65 in total

1

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3

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	8635	Xenbase:XB-GENE-944135
Mus musculus	68195	Xenbase:XB-GENE-944135	MOUSE20965
Xenopus tropicalis	190096	Xenbase:XB-GENE-944135
Rattus norvegicus	292306		RATNO17577
Bos taurus	508245		BOVIN36121
Macaca mulatta	706533		MACMU33434
Pan troglodytes	736033		PANTR39496
Xenopus tropicalis	791890	Xenbase:XB-GENE-944135
Xenopus tropicalis	855980	Xenbase:XB-GENE-944135
Mus musculus	100037283	Xenbase:XB-GENE-944135	MOUSE20965

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

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Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.2.1

Last updated: April 7, 2025