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Guidelines

MIRAGE

THO complex subunit 6

Summary

Gene Symbol

THOC6

Organism

Homo sapiens (human)

External Links

NCBI Gene

79228

PubChem

79228

Alliance of Genome Resources

HGNC:28369

Annotation

Keyword

3D-structure
Alternative splicing
Apoptosis
Developmental protein
Disease variant
Intellectual disability
Nucleus
Phosphoprotein
RNA-binding
Reference proteome
Repeat
WD repeat
mRNA splicing
mRNA transport

Proteins

Displaying 1 entry
UniProt	Protein Name
Q86W42	Functional spliceosome-associated protein 35 WD repeat-containing protein 58

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
apoptotic process	IEA
RNA splicing	IEA
mRNA export from nucleus	IBA IDA	17190602
mRNA processing	IEA
central nervous system development	IMP	23621916

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA metabolic process [inference]

mRNA processing

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA metabolic process [inference]

mRNA processing

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA metabolic process [inference]

mRNA processing

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA metabolic process [inference]

mRNA processing

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA metabolic process [inference]

mRNA processing

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA metabolic process [inference]

mRNA processing

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA metabolic process [inference]

mRNA processing

cellular process [inference]

cell death [inference]

programmed cell death [inference]

apoptotic process

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA metabolic process [inference]

mRNA processing

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA metabolic process [inference]

mRNA processing

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA metabolic process [inference]

mRNA processing

cellular localization [inference]

intracellular transport [inference]

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

developmental process [inference]

anatomical structure development [inference]

system development [inference]

central nervous system development

localization [inference]

establishment of localization [inference]

transport [inference]

intracellular transport [inference]

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

organic substance transport [inference]

nucleobase-containing compound transport [inference]

nucleic acid transport [inference]

RNA transport [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

mRNA transport [inference]

mRNA export from nucleus

nitrogen compound transport [inference]

nucleobase-containing compound transport [inference]

nucleic acid transport [inference]

RNA transport [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

mRNA transport [inference]

mRNA export from nucleus

establishment of RNA localization [inference]

RNA transport [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

mRNA transport [inference]

mRNA export from nucleus

establishment of localization in cell [inference]

intracellular transport [inference]

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

cellular localization [inference]

intracellular transport [inference]

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
nucleus	IDA	23621916
nuclear speck	IDA
THO complex	IBA IDA	15998806
nucleoplasm	IDA TAS
nuclear body	IDA

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

transcription export complex

THO complex part of transcription export complex

cellular anatomical entity [inference]

nucleoplasm

nuclear speck

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

chromosomal region [inference]

chromosome, telomeric region

Displaying 1 entry
GO Term	Evidence Code	PMID
RNA binding	IEA

GO Hierarchy

molecular function

binding [inference]

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying entries **41 - 50** of 71 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Pteropus vampyrus	105303126		PTEVA05719
Macaca nemestrina	105467890		MACNE25129
Mandrillus leucophaeus	105541540		MANLE28936
Cercocebus atys	105572059		CERAT18125
Aotus nancymaae	105709801		AOTNA20783
Propithecus coquereli	105813152		PROCO03498
Microcebus murinus	105859736		MICMU04113
Dipodomys ordii	105982243		DIPOR08143
Equus asinus asinus	106826044		EQUAS28194
Sinocyclocheilus grahami	107583000		SINGR30642

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Last updated: February 17, 2025