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activated leukocyte cell adhesion molecule

Summary

Gene Symbol

Alcam

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

79559

PubChem

79559

Alliance of Genome Resources

RGD:619972

Annotation

Keyword

Adaptive immunity
Cell adhesion
Cell membrane
Cell projection
Direct protein sequencing
Disulfide bond
Glycoprotein
Immunoglobulin domain
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
O35112	Activated leukocyte cell adhesion molecule HB2 KG-CAM Protein MEMD SB-10 antigen

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 8** of 8 in total

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GO Term	Evidence Code	PMID
axon extension involved in axon guidance	ISS
axon guidance	ISO
cell adhesion	IBA ISS

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

adaptive immune response

cellular process [inference]

cell-cell adhesion [inference]

cell-cell adhesion via plasma-membrane adhesion molecules [inference]

heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules

cell growth [inference]

developmental cell growth [inference]

neuron projection extension

axon extension [inference]

axon extension involved in axon guidance

neuron projection extension involved in neuron projection guidance [inference]

axon extension involved in axon guidance

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

neuron projection guidance [inference]

growth [inference]

cell growth [inference]

developmental cell growth [inference]

neuron projection extension

axon extension [inference]

axon extension involved in axon guidance

neuron projection extension involved in neuron projection guidance [inference]

axon extension involved in axon guidance

developmental growth [inference]

developmental cell growth [inference]

neuron projection extension

axon extension [inference]

axon extension involved in axon guidance

neuron projection extension involved in neuron projection guidance [inference]

axon extension involved in axon guidance

developmental growth involved in morphogenesis [inference]

neuron projection extension

axon extension [inference]

axon extension involved in axon guidance

neuron projection extension involved in neuron projection guidance [inference]

axon extension involved in axon guidance

response to stimulus [inference]

immune response [inference]

adaptive immune response

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
external side of plasma membrane	IEA ISO
neuronal cell body	IEA ISO
T cell receptor complex	IEA ISO ISS
plasma membrane	IBA IEA ISO ISS
dendrite	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex [inference]

plasma membrane signaling receptor complex [inference]

T cell receptor complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

plasma membrane signaling receptor complex [inference]

T cell receptor complex

cellular anatomical entity [inference]

immunological synapse

membrane [inference]

plasma membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

cell body [inference]

neuronal cell body

side of membrane [inference]

external side of plasma membrane

Displaying 1 entry
GO Term	Evidence Code	PMID
identical protein binding	IEA ISO

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

identical protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

CD166 antigen

Functional Category

D: Cell cycle control, cell division, chromosome partitioning
G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 5** entries
InterPro
CD80-like, immunoglobulin C2-set
Immunoglobulin subtype
Immunoglobulin-like domain superfamily
Immunoglobulin-like domain
Immunoglobulin-like fold

Ortholog

Displaying entries **1 - 10** of **127** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	214		HGNC:400	HUMAN71341
Mus musculus	11658	10090_1:004a72	MGI:1313266	MOUSE18059
Danio rerio	30194		ZFIN:ZDB-GENE-990415-30	DANRE00362
Bos taurus	281614			BOVIN14427
Danio rerio	323919		ZFIN:ZDB-GENE-030131-1768	DANRE08625
Sus scrofa	397269			PIGXX05771
Pan troglodytes	460565			PANTR31759
Canis lupus familiaris	478550			CANLF13261
Macaca mulatta	703777			MACMU28192
Xenopus tropicalis	780210		Xenbase:XB-GENE-491704

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Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024