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ring finger protein 128

Summary

Gene Symbol

RNF128

Organism

Homo sapiens (human)

External Links

NCBI Gene

79589

PubChem

79589

Alliance of Genome Resources

HGNC:21153

JoGo

RNF128

TogoVar

RNF128

Annotation

Keyword

3D-structure
Alternative splicing
Cytoskeleton
Glycoprotein
Proteomics identification
Reference proteome
Signal
Transferase
Transmembrane helix
Ubl conjugation
Ubl conjugation pathway
Zinc-finger

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8TEB7	Gene related to anergy in lymphocytes protein RING finger protein 128 RING-type E3 ubiquitin transferase RNF128

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
negative regulation of cytokine production	IEA
ubiquitin-dependent protein catabolic process	NAS	25635054
ubiquitin-dependent protein catabolic process	IBA
protein ubiquitination	IEA
regulation of protein stability	IMP	25635054

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

catabolic process [inference]

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

macromolecule modification [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

cellular process [inference]

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to vacuole [inference]

protein localization to lysosome

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to vacuole [inference]

protein localization to lysosome

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to vacuole [inference]

protein localization to lysosome

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of protein catabolic process in the vacuole

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of protein catabolic process in the vacuole

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of protein catabolic process in the vacuole

regulation of catabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of protein catabolic process in the vacuole

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of protein catabolic process in the vacuole

regulation of protein catabolic process in the vacuole [inference]

positive regulation of protein catabolic process in the vacuole

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

regulation of nitrogen compound metabolic process [inference]

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of protein catabolic process in the vacuole

regulation of protein metabolic process [inference]

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of protein catabolic process in the vacuole

regulation of protein catabolic process in the vacuole [inference]

positive regulation of protein catabolic process in the vacuole

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of protein catabolic process in the vacuole

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of protein catabolic process in the vacuole

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

regulation of protein metabolic process [inference]

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of protein catabolic process in the vacuole

regulation of protein catabolic process in the vacuole [inference]

positive regulation of protein catabolic process in the vacuole

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of protein catabolic process in the vacuole

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of protein catabolic process in the vacuole

regulation of protein catabolic process in the vacuole [inference]

positive regulation of protein catabolic process in the vacuole

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of protein catabolic process in the vacuole

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of protein catabolic process in the vacuole

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of protein catabolic process in the vacuole

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of protein catabolic process in the vacuole

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of multicellular organismal process [inference]

negative regulation of cytokine production

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production

negative regulation of multicellular organismal process [inference]

negative regulation of cytokine production

regulation of biological quality [inference]

regulation of protein stability

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
cytoplasm	IBA
late endosome	IBA
endoplasmic reticulum	IBA
Golgi apparatus	IBA
cytosol	TAS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

late endosome

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

late endosome

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

late endosome

intracellular non-membrane-bounded organelle [inference]

cytoskeleton

perinuclear region of cytoplasm

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein binding	IPI	25416956 32296183
zinc ion binding	IEA
metal ion binding
ubiquitin protein ligase activity	TAS	25635054
ubiquitin protein ligase activity	IBA