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NLR family member X1

Summary

Gene Symbol

NLRX1

Organism

Homo sapiens (human)

External Links

NCBI Gene

79671

PubChem

79671

Alliance of Genome Resources

HGNC:29890

Annotation

Keyword

3D-structure
ATP-binding
Alternative splicing
Host-virus interaction
Innate immunity
Leucine-rich repeat
Mitochondrion outer membrane
Reference proteome
Repeat
Transit peptide

Proteins

Displaying 1 entry
UniProt	Protein Name
Q86UT6	Caterpiller protein 11.3 Nucleotide-binding oligomerization domain protein 5 Nucleotide-binding oligomerization domain protein 9

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

1

2

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Last »
GO Term	Evidence Code	PMID
negative regulation of macrophage cytokine production	IEA
negative regulation of interferon-beta production	IEA
negative regulation of interleukin-6 production	IEA
negative regulation of RIG-I signaling pathway	IEA
negative regulation of canonical NF-kappaB signal transduction	IBA

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

innate immune response

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

innate immune response

immune response [inference]

innate immune response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

negative regulation of immune system process [inference]

negative regulation of immune effector process [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of RIG-I signaling pathway

negative regulation of immune response [inference]

negative regulation of innate immune response

regulation of immune effector process [inference]

negative regulation of immune effector process [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of production of molecular mediator of immune response [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of cytokine production involved in immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

negative regulation of macrophage cytokine production

regulation of immune response [inference]

regulation of innate immune response [inference]

negative regulation of innate immune response

regulation of pattern recognition receptor signaling pathway [inference]

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of RIG-I signaling pathway

regulation of RIG-I signaling pathway [inference]

negative regulation of RIG-I signaling pathway

negative regulation of immune response [inference]

negative regulation of innate immune response

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

regulation of cytokine production involved in immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

negative regulation of macrophage cytokine production

regulation of type I interferon production [inference]

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

regulation of interferon-beta production [inference]

negative regulation of interferon-beta production

regulation of interleukin-6 production [inference]

negative regulation of interleukin-6 production

regulation of production of molecular mediator of immune response [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of cytokine production involved in immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

negative regulation of macrophage cytokine production

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

regulation of cytokine production involved in immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

negative regulation of macrophage cytokine production

regulation of type I interferon production [inference]

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

regulation of interferon-beta production [inference]

negative regulation of interferon-beta production

regulation of interleukin-6 production [inference]

negative regulation of interleukin-6 production

regulation of production of molecular mediator of immune response [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of cytokine production involved in immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

negative regulation of macrophage cytokine production

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

regulation of cytokine production involved in immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

negative regulation of macrophage cytokine production

regulation of type I interferon production [inference]

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

regulation of interferon-beta production [inference]

negative regulation of interferon-beta production

regulation of interleukin-6 production [inference]

negative regulation of interleukin-6 production

regulation of production of molecular mediator of immune response [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of cytokine production involved in immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

negative regulation of macrophage cytokine production

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of RIG-I signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

regulation of pattern recognition receptor signaling pathway [inference]

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of RIG-I signaling pathway

regulation of RIG-I signaling pathway [inference]

negative regulation of RIG-I signaling pathway

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of RIG-I signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of immune effector process [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of RIG-I signaling pathway

negative regulation of immune response [inference]

negative regulation of innate immune response

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of RIG-I signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of RIG-I signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of response to stimulus [inference]

negative regulation of response to biotic stimulus [inference]

negative regulation of innate immune response

negative regulation of signal transduction [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of RIG-I signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of defense response [inference]

negative regulation of response to external stimulus [inference]

negative regulation of immune response [inference]

negative regulation of innate immune response

negative regulation of multicellular organismal process [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

regulation of response to stimulus [inference]

regulation of response to biotic stimulus [inference]

negative regulation of response to biotic stimulus [inference]

negative regulation of innate immune response

regulation of innate immune response [inference]

negative regulation of innate immune response

regulation of pattern recognition receptor signaling pathway [inference]

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of RIG-I signaling pathway

regulation of RIG-I signaling pathway [inference]

negative regulation of RIG-I signaling pathway

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of RIG-I signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

regulation of pattern recognition receptor signaling pathway [inference]

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of RIG-I signaling pathway

regulation of RIG-I signaling pathway [inference]

negative regulation of RIG-I signaling pathway

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

regulation of response to external stimulus [inference]

negative regulation of response to external stimulus [inference]

regulation of innate immune response [inference]

negative regulation of innate immune response

regulation of pattern recognition receptor signaling pathway [inference]

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of RIG-I signaling pathway

regulation of RIG-I signaling pathway [inference]

negative regulation of RIG-I signaling pathway

regulation of inflammatory response [inference]

negative regulation of inflammatory response

negative regulation of response to stimulus [inference]

negative regulation of response to biotic stimulus [inference]

negative regulation of innate immune response

negative regulation of signal transduction [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of RIG-I signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of defense response [inference]

negative regulation of response to external stimulus [inference]

negative regulation of immune response [inference]

negative regulation of innate immune response

regulation of immune response [inference]

regulation of innate immune response [inference]

negative regulation of innate immune response

regulation of pattern recognition receptor signaling pathway [inference]

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of RIG-I signaling pathway

regulation of RIG-I signaling pathway [inference]

negative regulation of RIG-I signaling pathway

negative regulation of immune response [inference]

negative regulation of innate immune response

regulation of response to stress [inference]

regulation of defense response [inference]

negative regulation of defense response [inference]

regulation of innate immune response [inference]

negative regulation of innate immune response

regulation of pattern recognition receptor signaling pathway [inference]

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of RIG-I signaling pathway

regulation of RIG-I signaling pathway [inference]

negative regulation of RIG-I signaling pathway

regulation of inflammatory response [inference]

negative regulation of inflammatory response

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of RIG-I signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

regulation of pattern recognition receptor signaling pathway [inference]

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of RIG-I signaling pathway

regulation of RIG-I signaling pathway [inference]

negative regulation of RIG-I signaling pathway

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of RIG-I signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

regulation of cytokine production involved in immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

negative regulation of macrophage cytokine production

regulation of type I interferon production [inference]

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

regulation of interferon-beta production [inference]

negative regulation of interferon-beta production

regulation of interleukin-6 production [inference]

negative regulation of interleukin-6 production

regulation of production of molecular mediator of immune response [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of cytokine production involved in immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

negative regulation of macrophage cytokine production

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of RIG-I signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of canonical NF-kappaB signal transduction

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

regulation of cytokine production involved in immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

negative regulation of macrophage cytokine production

regulation of type I interferon production [inference]

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

regulation of interferon-beta production [inference]

negative regulation of interferon-beta production

regulation of interleukin-6 production [inference]

negative regulation of interleukin-6 production

negative regulation of multicellular organismal process [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of type I interferon production [inference]

negative regulation of interferon-beta production

negative regulation of interleukin-6 production

Displaying entries **1 - 5** of 6 in total

1

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Last »
GO Term	Evidence Code	PMID
mitochondrion	IDA
mitochondrion	IBA
mitochondrion	HTP	34800366
mitochondrial outer membrane	TAS
cytosol	TAS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

membrane [inference]

plasma membrane

outer membrane [inference]

organelle outer membrane [inference]

mitochondrial outer membrane

organelle membrane [inference]

mitochondrial membrane [inference]

mitochondrial outer membrane

bounding membrane of organelle [inference]

organelle outer membrane [inference]

mitochondrial outer membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein binding	IPI	18200010 21903422 28611246
ATP binding	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

NLR family member X1

Functional Category

O: Posttranslational modification, protein turnover, chaperones
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
negative regulation of canonical NF-kappaB signal transduction

Displaying **all 5** entries
InterPro
Leucine-rich repeat domain superfamily
Leucine-rich repeat
NACHT nucleoside triphosphatase
NLR family member X1, C-terminal domain
P-loop containing nucleoside triphosphate hydrolase

Ortholog

Displaying entries **1 - 10** of 95 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	79671	Xenbase:XB-GENE-6039800
Mus musculus	270151	Xenbase:XB-GENE-6039800	MOUSE62410
Rattus norvegicus	315599		RATNO40604
Pan troglodytes	451605		PANTR04542
Canis lupus familiaris	489370		CANLF15202
Bos taurus	539974		BOVIN06601
Danio rerio	557335		DANRE08560
Macaca mulatta	703981		MACMU09206
Monodelphis domestica	100031223		MONDO23971
Equus caballus	100071383		HORSE39393

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements