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MIRAGE
gasdermin D
Summary
- Gene Symbol
-
- GSDMD
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Cell membrane
- Direct protein sequencing
- Glycoprotein
- Inflammasome
- Inflammatory response
- Innate immunity
- Lipid-binding
- Mitochondrion
- Necrosis
- Nucleus
- Palmitate
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Secreted
- Transcription regulation
- Transmembrane beta strand
- Ubl conjugation
- Proteins
| UniProt | Protein Name |
|---|---|
| P57764 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein secretion | ||
| positive regulation of interleukin-1 beta production | ||
| positive regulation of interleukin-1 production | ||
| positive regulation of interleukin-18 production | ||
| defense response to bacterium |
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of macromolecule metabolic process [inference]
positive regulation of biological process [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| extracellular space | ||
| nucleoplasm | ||
| cytosol | ||
| cytosol |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| phosphatidylserine binding | ||
| phosphatidylserine binding | ||
| protein binding | ||
| phosphatidylinositol-4,5-bisphosphate binding | ||
| phosphatidylinositol-4,5-bisphosphate binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- gasdermin-D
- Functional Category
-
- G: Carbohydrate transport and metabolism
- J: Translation, ribosomal structure and biogenesis
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| phosphatidylinositol-4,5-bisphosphate binding |
| phosphatidylinositol-4-phosphate binding |
| phosphatidylserine binding |
| pyroptosis |
| InterPro |
|---|
| Gasdermin, PUB domain |
| Gasdermin, pore forming domain |
