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myostatin b

Summary

Gene Symbol

mstnb

Organism

Danio rerio (zebrafish)

External Links

NCBI Gene

798441

PubChem

798441

Alliance of Genome Resources

ZFIN:ZDB-GENE-990415-165

Annotation

Keyword

Cleavage on pair of basic residues
Cytokine
Disulfide bond
Glycoprotein
Growth factor
Reference proteome
Secreted
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
O42222	Myostatin Myostatin-1 Myostatin-B

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
ventricular trabecula myocardium morphogenesis	IMP	29196619
immune response	IMP	29175471
transforming growth factor beta receptor signaling pathway	IDA	14555747
muscle organ development	IDA	15042708
skeletal muscle tissue development	IDA	19517013

GO Hierarchy

biological process

immune system process [inference]

immune response

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

transforming growth factor beta receptor signaling pathway

cell population proliferation [inference]

myoblast proliferation [inference]

cardiac muscle myoblast proliferation

developmental process [inference]

anatomical structure morphogenesis [inference]

tissue morphogenesis [inference]

muscle tissue morphogenesis [inference]

cardiac muscle tissue morphogenesis [inference]

ventricular cardiac muscle tissue morphogenesis [inference]

ventricular trabecula myocardium morphogenesis

trabecula morphogenesis [inference]

heart trabecula morphogenesis [inference]

ventricular trabecula myocardium morphogenesis

anatomical structure development [inference]

tissue development [inference]

muscle tissue development [inference]

skeletal muscle tissue development

animal organ development [inference]

muscle organ development

muscle structure development [inference]

muscle organ development

response to stimulus [inference]

immune response

biological regulation [inference]

regulation of biological process [inference]

regulation of growth [inference]

regulation of growth rate [inference]

negative regulation of growth rate

negative regulation of growth

negative regulation of growth rate

negative regulation of biological process [inference]

negative regulation of growth

negative regulation of growth rate

negative regulation of cellular process [inference]

negative regulation of cell population proliferation [inference]

negative regulation of myoblast proliferation [inference]

negative regulation of cardiac muscle myoblast proliferation

negative regulation of developmental process [inference]

negative regulation of muscle organ development [inference]

negative regulation of striated muscle tissue development

negative regulation of muscle tissue development [inference]

negative regulation of multicellular organismal process [inference]

negative regulation of muscle organ development [inference]

negative regulation of striated muscle tissue development

regulation of response to stimulus [inference]

regulation of muscle adaptation [inference]

regulation of muscle hyperplasia

regulation of developmental process [inference]

regulation of muscle organ development [inference]

regulation of striated muscle tissue development [inference]

negative regulation of striated muscle tissue development

negative regulation of muscle organ development [inference]

negative regulation of striated muscle tissue development

negative regulation of developmental process [inference]

negative regulation of muscle organ development [inference]

negative regulation of striated muscle tissue development

negative regulation of muscle tissue development [inference]

regulation of muscle tissue development [inference]

regulation of striated muscle tissue development [inference]

negative regulation of striated muscle tissue development

regulation of skeletal muscle tissue development [inference]

negative regulation of skeletal muscle tissue development

negative regulation of muscle tissue development [inference]

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

transforming growth factor beta receptor signaling pathway

regulation of cell population proliferation [inference]

negative regulation of cell population proliferation [inference]

negative regulation of myoblast proliferation [inference]

negative regulation of cardiac muscle myoblast proliferation

regulation of myoblast proliferation [inference]

regulation of cardiac muscle myoblast proliferation [inference]

negative regulation of cardiac muscle myoblast proliferation

negative regulation of myoblast proliferation [inference]

negative regulation of cardiac muscle myoblast proliferation

negative regulation of cellular process [inference]

negative regulation of cell population proliferation [inference]

negative regulation of myoblast proliferation [inference]

negative regulation of cardiac muscle myoblast proliferation

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of muscle system process [inference]

regulation of muscle adaptation [inference]

regulation of muscle hyperplasia

negative regulation of multicellular organismal process [inference]

negative regulation of muscle organ development [inference]

negative regulation of striated muscle tissue development

Displaying **all 3** entries
GO Term	Evidence Code	PMID
extracellular region	IEA
extracellular space	IBA
extracellular space	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

Displaying **all 4** entries
GO Term	Evidence Code	PMID
cytokine activity	IBA
cytokine activity	IEA
growth factor activity	IDA	15042708
growth factor activity	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

receptor ligand activity [inference]

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Nodal

Functional Category

K: Transcription
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
cytokine activity
growth factor activity

Displaying **all 5** entries
InterPro
Cystine-knot cytokine
TGF-beta, propeptide
Transforming growth factor beta, conserved site
Transforming growth factor-beta, C-terminal
Transforming growth factor-beta-related

Ortholog

Displaying entries **1 - 10** of 95 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	2660	Xenbase:XB-GENE-483324	HUMAN66024
Drosophila melanogaster	10220	FB:FBgn0026199
Drosophila melanogaster	14561	FB:FBgn0026199
Mus musculus	17700	Xenbase:XB-GENE-483324	MOUSE27963
Rattus norvegicus	29152	Xenbase:XB-GENE-483324	RATNO42291
Drosophila melanogaster	29454	FB:FBgn0026199
Xenopus tropicalis	175237	Xenbase:XB-GENE-483324
Bos taurus	281187		BOVIN23894
Sus scrofa	399534		PIGXX09660
Canis lupus familiaris	403433		CANLF14056