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valosin containing protein interacting protein 1

Summary

Gene Symbol

VCPIP1

Organism

Homo sapiens (human)

External Links

NCBI Gene

80124

PubChem

80124

Alliance of Genome Resources

HGNC:30897

Annotation

Keyword

Acetylation
Cytoplasm
DNA repair
Endoplasmic reticulum
Golgi apparatus
Nucleus
Phosphoprotein
Reference proteome
Thiol protease
Ubl conjugation pathway

Proteins

Displaying 1 entry
UniProt	Protein Name
Q96JH7	Valosin-containing protein p97/p47 complex-interacting protein 1 Valosin-containing protein p97/p47 complex-interacting protein p135

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 10** of 11 in total

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GO Term	Evidence Code	PMID
DNA damage response	IDA	32649882
protein K11-linked deubiquitination	IDA	23827681
cellular response to DNA damage stimulus	IDA	32649882
protein-DNA covalent cross-linking repair	IBA IDA	32649882
regulation of protein localization to chromatin	IDA	32649882

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

protein-DNA covalent cross-linking repair

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

protein modification by small protein removal [inference]

protein deubiquitination

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

protein-DNA covalent cross-linking repair

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

protein-DNA covalent cross-linking repair

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

protein-DNA covalent cross-linking repair

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

protein-DNA covalent cross-linking repair

protein metabolic process [inference]

proteolysis

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

protein modification by small protein removal [inference]

protein deubiquitination

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

protein modification by small protein removal [inference]

protein deubiquitination

macromolecule modification [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

protein modification by small protein removal [inference]

protein deubiquitination

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

protein-DNA covalent cross-linking repair

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

protein-DNA covalent cross-linking repair

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

protein modification by small protein removal [inference]

protein deubiquitination

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

protein-DNA covalent cross-linking repair

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

protein-DNA covalent cross-linking repair

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

protein-DNA covalent cross-linking repair

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to DNA damage stimulus

DNA repair [inference]

protein-DNA covalent cross-linking repair

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

endoplasmic reticulum organization [inference]

endoplasmic reticulum membrane fusion

Golgi organization [inference]

Golgi reassembly

organelle fusion [inference]

organelle membrane fusion [inference]

endoplasmic reticulum membrane fusion

cellular component assembly [inference]

Golgi reassembly

membrane organization [inference]

membrane fusion [inference]

organelle membrane fusion [inference]

endoplasmic reticulum membrane fusion

endoplasmic reticulum membrane organization [inference]

endoplasmic reticulum membrane fusion

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

cellular response to DNA damage stimulus

DNA repair [inference]

protein-DNA covalent cross-linking repair

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to DNA damage stimulus

DNA repair [inference]

protein-DNA covalent cross-linking repair

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of protein localization to chromatin

regulation of cellular process [inference]

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of protein localization to chromatin

Displaying **all 4** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum lumen	TAS
Golgi stack	IEA
nucleus	IDA	32649882
cytoplasm	IDA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

endoplasmic reticulum lumen

organelle subcompartment [inference]

Golgi apparatus subcompartment [inference]

Golgi stack

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein binding	IPI	28514442 33961781
cysteine-type deubiquitinase activity	IBA IDA ISS	23827681 32649882

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

cysteine-type peptidase activity [inference]

cysteine-type deubiquitinase activity

ubiquitin-like protein peptidase activity [inference]

deubiquitinase activity [inference]

cysteine-type deubiquitinase activity

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

cysteine-type peptidase activity [inference]

cysteine-type deubiquitinase activity

ubiquitin-like protein peptidase activity [inference]

deubiquitinase activity [inference]

cysteine-type deubiquitinase activity

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Deubiquitinating protein

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
Golgi reassembly
endoplasmic reticulum membrane fusion
hydrolase activity
protein ubiquitination

Displaying **all 5** entries
InterPro
Deubiquitinating protein VCPIP1, N-terminal
Deubiquitinating protein VCPIP1
OTU domain
OTU1, Ubl domain
Ubiquitin-like domain superfamily

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:3911	progeria	Alliance of Genome Resources

Ortholog

Displaying entries **71 - 80** of **103** in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Sinocyclocheilus grahami	107567007		SINGR92365
Sinocyclocheilus grahami	107602633		SINGR65421
Kryptolebias marmoratus	108251343		KRYMA28463
Pygocentrus nattereri	108428332		PYGNA10408
Rhinopithecus bieti	108544904		RHIBE25459
Xenopus laevis	108695326	Xenbase:XB-GENE-6487477
Xenopus laevis	108719278	Xenbase:XB-GENE-17332775
Cyprinus carpio carpio	109049696		CYPCA42000
Cyprinus carpio carpio	109051728		CYPCA70344
Crocodylus porosus	109319316		CROPO02341