GlyCosmos Portal

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GO Term	Evidence Code	PMID
aminoacyl-tRNA editing activity	IDA	26811336
threonine-tRNA ligase activity	IDA	26811336
threonine-tRNA ligase activity	IBA
protein binding	IPI	32296183
ATP binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

carboxylic ester hydrolase activity [inference]

aminoacyl-tRNA editing activity

ligase activity [inference]

ligase activity, forming carbon-oxygen bonds [inference]

aminoacyl-tRNA ligase activity [inference]

threonine-tRNA ligase activity

catalytic activity, acting on a nucleic acid [inference]

catalytic activity, acting on RNA [inference]

catalytic activity, acting on a tRNA [inference]

aminoacyl-tRNA editing activity

aminoacyl-tRNA ligase activity [inference]

threonine-tRNA ligase activity

binding [inference]

protein binding

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Threonine--trna ligase

Functional Category

J: Translation, ribosomal structure and biogenesis
K: Transcription
T: Signal transduction mechanisms

Displaying **all 7** entries
Gene Ontology
ATP binding
ligase activity
nucleotide binding
tRNA aminoacylation for protein translation
tRNA aminoacylation
threonine-tRNA ligase activity
threonyl-tRNA aminoacylation

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InterPro
Aminoacyl-tRNA synthetase, class II (G/ P/ S/T)
Aminoacyl-tRNA synthetase, class II
Anticodon-binding domain superfamily
Anticodon-binding
Beta-grasp domain superfamily
Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL)
TGS-like
TGS
Threonine-tRNA ligase catalytic core domain
Threonine-tRNA ligase, class IIa, anticodon-binding domain

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0111465	combined oxidative phosphorylation deficiency 21	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 44 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Saccharomyces cerevisiae S288C	6897	SGD:S000001340
Mus musculus	71807		MOUSE37237
Xenopus tropicalis	80222	Xenbase:XB-GENE-996801
Saccharomyces cerevisiae S288C	110960	SGD:S000001340
Saccharomyces cerevisiae S288C	123283	SGD:S000001340
Rattus norvegicus	310672		RATNO23217
Bos taurus	511740		BOVIN26038
Canis lupus familiaris	608006		CANLF05376
Macaca mulatta	707105		MACMU25727
Pan troglodytes	746922		PANTR22165

GlyTouCan

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Acknowledgements