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taste 1 receptor member 2

Summary

Gene Symbol

TAS1R2

Organism

Homo sapiens (human)

External Links

NCBI Gene

80834

PubChem

80834

Alliance of Genome Resources

HGNC:14905

Annotation

Keyword

Cell membrane
G-protein coupled receptor
Glycoprotein
Proteomics identification
Reference proteome
Signal
Taste
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8TE23	G-protein coupled receptor 71 Sweet taste receptor T1R2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
detection of chemical stimulus involved in sensory perception of sweet taste	IDA	16720576
G protein-coupled receptor signaling pathway	IC	16720576
positive regulation of cytokinesis	IMP	22888021
sensory perception of sweet taste	IDA	11917125
sensory perception of sweet taste	IBA

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of chemical stimulus [inference]

sensory perception of taste [inference]

sensory perception of sweet taste

response to stimulus [inference]

detection of stimulus [inference]

detection of chemical stimulus [inference]

detection of chemical stimulus involved in sensory perception [inference]

detection of chemical stimulus involved in sensory perception of taste [inference]

detection of chemical stimulus involved in sensory perception of sweet taste

detection of stimulus involved in sensory perception [inference]

detection of chemical stimulus involved in sensory perception [inference]

detection of chemical stimulus involved in sensory perception of taste [inference]

detection of chemical stimulus involved in sensory perception of sweet taste

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell cycle [inference]

positive regulation of cell cycle process [inference]

positive regulation of cytokinesis

positive regulation of cell division [inference]

positive regulation of cytokinesis

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

positive regulation of cellular process [inference]

positive regulation of cell cycle [inference]

positive regulation of cell cycle process [inference]

positive regulation of cytokinesis

positive regulation of cell division [inference]

positive regulation of cytokinesis

regulation of cell division [inference]

regulation of cytokinesis [inference]

positive regulation of cytokinesis

positive regulation of cell division [inference]

positive regulation of cytokinesis

regulation of cell cycle [inference]

regulation of cell cycle process [inference]

regulation of cytokinesis [inference]

positive regulation of cytokinesis

positive regulation of cell cycle process [inference]

positive regulation of cytokinesis

positive regulation of cell cycle [inference]

positive regulation of cell cycle process [inference]

positive regulation of cytokinesis

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
plasma membrane	TAS
plasma membrane	IBA
membrane	IC	11917125
receptor complex	IDA	23382219
sweet taste receptor complex	IDA	16720576

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex

taste receptor complex [inference]

sweet taste receptor complex

cellular anatomical entity [inference]

membrane

plasma membrane

Displaying **all 5** entries
GO Term	Evidence Code	PMID
G protein-coupled receptor activity	IBA
taste receptor activity	IDA	16720576
taste receptor activity	IPI	11917125
sweet taste receptor activity	IDA	16720576
sweet taste receptor activity	IBA

GO Hierarchy

molecular function

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity

taste receptor activity

sweet taste receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Receptor

Functional Category

E: Amino acid transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
ligand-gated monoatomic ion channel activity
monoatomic ion transport

Displaying **all 2** entries
InterPro
Periplasmic binding protein-like I
Receptor, ligand binding region

Ortholog

Displaying entries **1 - 10** of 58 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Danio rerio	80834	ZFIN:ZDB-GENE-070917-1
Mus musculus	83770	ZFIN:ZDB-GENE-070917-2	MOUSE41716
Canis lupus familiaris	478213		CANLF07100
Bos taurus	529847		BOVIN25353
Rattus norvegicus	641315		RATNO33707
Rattus norvegicus	641316		RATNO33707
Macaca mulatta	714666		MACMU22750
Ornithorhynchus anatinus	100090052		ORNAN23015
Rattus norvegicus	100270683		RATNO33707
Callithrix jacchus	100386065		CALJA39347