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actinin alpha 4
Summary
- Gene Symbol
-
- ACTN4
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Actin-binding
- Alternative splicing
- Calcium
- Cell junction
- Coiled coil
- Cytoskeleton
- Disease variant
- Metal-binding
- Nucleus
- Phosphoprotein
- Protein transport
- Proteomics identification
- Reference proteome
- Repeat
- Proteins
| UniProt | Protein Name |
|---|---|
| O43707 |
|
| H7C144 |
|
| F5GXS2 |
|
| A0A0S2Z3G9 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein transport | ||
| actin cytoskeleton organization | ||
| vesicle transport along actin filament | ||
| positive regulation of cell migration | ||
| positive regulation of sodium:proton antiporter activity |
GO Hierarchy
biological process
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of localization [inference]
regulation of transport [inference]
regulation of transmembrane transport [inference]
regulation of monoatomic ion transport [inference]
positive regulation of biological process [inference]
regulation of cellular process [inference]
regulation of cellular metabolic process [inference]
regulation of transmembrane transport [inference]
positive regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| RNA polymerase II transcription regulatory region sequence-specific DNA binding | ||
| nucleoside binding | ||
| transcription coactivator activity | ||
| RNA binding | ||
| actin binding |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Alpha actinin
- Functional Category
-
- E: Amino acid transport and metabolism
- K: Transcription
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| actin binding |
| actin cytoskeleton organization |
| actin filament binding |
| calcium ion binding |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0111128 | focal segmental glomerulosclerosis 1 | |
| DOID:1312 | focal segmental glomerulosclerosis |
