GlyCosmos Portal

Submissions

solute carrier family 2 member 10

Summary

Gene Symbol

SLC2A10

Aliases

GLUT-10
GLUT10
facilitative glucose transporter GLUT10

Organism

Homo sapiens (human)

External Links

NCBI Gene

81031

HGNC

13444

KEGG Gene ID

hsa:81031

PubChem

81031

Alliance of Genome Resources

HGNC:13444

Annotation

Keyword

Cytoplasm
Disease variant
Glycoprotein
Reference proteome
Sugar transport
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
O95528	Glucose transporter type 10

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 10** of 21 in total

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GO Term	Evidence Code	PMID
circulatory system development	IBA
negative regulation of connective tissue growth factor production	IMP	16550171 26376865
transport across blood-brain barrier		30280653
positive regulation of transforming growth factor beta receptor signaling pathway	IMP	26376865
positive regulation of proteoglycan biosynthetic process	IMP	16550171

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport [inference]

carbohydrate transmembrane transport [inference]

monosaccharide transmembrane transport [inference]

hexose transmembrane transport

galactose transmembrane transport

hexose import across plasma membrane [inference]

glucose import across plasma membrane

glucose transmembrane transport

glucose import across plasma membrane

carbohydrate import across plasma membrane [inference]

hexose import across plasma membrane [inference]

glucose import across plasma membrane

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

proton transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

proton transmembrane transport

import across plasma membrane [inference]

carbohydrate import across plasma membrane [inference]

hexose import across plasma membrane [inference]

glucose import across plasma membrane

multicellular organismal process [inference]

system process [inference]

circulatory system process [inference]

vascular process in circulatory system [inference]

vascular transport [inference]

transport across blood-brain barrier

developmental process [inference]

anatomical structure development [inference]

blood vessel development [inference]

artery development

animal organ development [inference]

skin development

system development [inference]

skeletal system development [inference]

embryonic skeletal system development [inference]

embryonic skeletal joint development

circulatory system development

homeostatic process [inference]

cellular homeostasis [inference]

cell redox homeostasis

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

monoatomic cation transmembrane transport [inference]

proton transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

proton transmembrane transport

vascular transport [inference]

transport across blood-brain barrier

vitamin transport [inference]

dehydroascorbic acid transport

transmembrane transport [inference]

carbohydrate transmembrane transport [inference]

monosaccharide transmembrane transport [inference]

hexose transmembrane transport

galactose transmembrane transport

hexose import across plasma membrane [inference]

glucose import across plasma membrane

glucose transmembrane transport

glucose import across plasma membrane

carbohydrate import across plasma membrane [inference]

hexose import across plasma membrane [inference]

glucose import across plasma membrane

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

proton transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

proton transmembrane transport

import across plasma membrane [inference]

carbohydrate import across plasma membrane [inference]

hexose import across plasma membrane [inference]

glucose import across plasma membrane

organic substance transport [inference]

carbohydrate transport [inference]

carbohydrate transmembrane transport [inference]

monosaccharide transmembrane transport [inference]

hexose transmembrane transport

galactose transmembrane transport

hexose import across plasma membrane [inference]

glucose import across plasma membrane

glucose transmembrane transport

glucose import across plasma membrane

carbohydrate import across plasma membrane [inference]

hexose import across plasma membrane [inference]

glucose import across plasma membrane

organic anion transport [inference]

dehydroascorbic acid transport

import into cell [inference]

carbohydrate import across plasma membrane [inference]

hexose import across plasma membrane [inference]

glucose import across plasma membrane

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of proteoglycan biosynthetic process

negative regulation of gene expression

negative regulation of cytokine production [inference]

negative regulation of connective tissue growth factor production

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of glycoprotein biosynthetic process [inference]

positive regulation of proteoglycan biosynthetic process

positive regulation of gene expression

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of connective tissue growth factor production

regulation of connective tissue growth factor production [inference]

negative regulation of connective tissue growth factor production

positive regulation of gene expression

negative regulation of gene expression

negative regulation of cytokine production [inference]

negative regulation of connective tissue growth factor production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of glycoprotein biosynthetic process [inference]

positive regulation of proteoglycan biosynthetic process

positive regulation of gene expression

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of proteoglycan biosynthetic process

negative regulation of gene expression

negative regulation of cytokine production [inference]

negative regulation of connective tissue growth factor production

regulation of glycoprotein biosynthetic process [inference]

positive regulation of glycoprotein biosynthetic process [inference]

positive regulation of proteoglycan biosynthetic process

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of proteoglycan biosynthetic process

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of proteoglycan biosynthetic process

negative regulation of gene expression

negative regulation of cytokine production [inference]

negative regulation of connective tissue growth factor production

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of glycoprotein biosynthetic process [inference]

positive regulation of proteoglycan biosynthetic process

positive regulation of gene expression

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of proteoglycan biosynthetic process

negative regulation of gene expression

negative regulation of cytokine production [inference]

negative regulation of connective tissue growth factor production

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of proteoglycan biosynthetic process

negative regulation of gene expression

negative regulation of cytokine production [inference]

negative regulation of connective tissue growth factor production

negative regulation of protein metabolic process [inference]

negative regulation of glycoprotein metabolic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of proteoglycan biosynthetic process

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of proteoglycan biosynthetic process

negative regulation of gene expression

negative regulation of cytokine production [inference]

negative regulation of connective tissue growth factor production

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of glycoprotein metabolic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of proteoglycan biosynthetic process

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of glycoprotein biosynthetic process [inference]

positive regulation of proteoglycan biosynthetic process

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of glycoprotein biosynthetic process [inference]

positive regulation of proteoglycan biosynthetic process

positive regulation of gene expression

positive regulation of protein metabolic process [inference]

positive regulation of glycoprotein metabolic process [inference]

positive regulation of glycoprotein biosynthetic process [inference]

positive regulation of proteoglycan biosynthetic process

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of glycoprotein biosynthetic process [inference]

positive regulation of proteoglycan biosynthetic process

positive regulation of gene expression

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of glycoprotein metabolic process [inference]

positive regulation of glycoprotein biosynthetic process [inference]

positive regulation of proteoglycan biosynthetic process

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of proteoglycan biosynthetic process

negative regulation of gene expression

negative regulation of cytokine production [inference]

negative regulation of connective tissue growth factor production

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of glycoprotein biosynthetic process [inference]

positive regulation of proteoglycan biosynthetic process

positive regulation of gene expression

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of connective tissue growth factor production

regulation of connective tissue growth factor production [inference]

negative regulation of connective tissue growth factor production

positive regulation of gene expression

negative regulation of gene expression

negative regulation of cytokine production [inference]

negative regulation of connective tissue growth factor production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of glycoprotein biosynthetic process [inference]

positive regulation of proteoglycan biosynthetic process

positive regulation of gene expression

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of proteoglycan biosynthetic process

negative regulation of gene expression

negative regulation of cytokine production [inference]

negative regulation of connective tissue growth factor production

regulation of glycoprotein biosynthetic process [inference]

positive regulation of glycoprotein biosynthetic process [inference]

positive regulation of proteoglycan biosynthetic process

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of proteoglycan biosynthetic process

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of proteoglycan biosynthetic process

negative regulation of gene expression

negative regulation of cytokine production [inference]

negative regulation of connective tissue growth factor production

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of glycoprotein biosynthetic process [inference]

positive regulation of proteoglycan biosynthetic process

positive regulation of gene expression

regulation of nitrogen compound metabolic process [inference]

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of glycoprotein metabolic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of proteoglycan biosynthetic process

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of glycoprotein metabolic process [inference]

positive regulation of glycoprotein biosynthetic process [inference]

positive regulation of proteoglycan biosynthetic process

regulation of protein metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of glycoprotein metabolic process [inference]

positive regulation of glycoprotein biosynthetic process [inference]

positive regulation of proteoglycan biosynthetic process

negative regulation of protein metabolic process [inference]

negative regulation of glycoprotein metabolic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of proteoglycan biosynthetic process

regulation of glycoprotein metabolic process [inference]

regulation of glycoprotein biosynthetic process [inference]

positive regulation of glycoprotein biosynthetic process [inference]

positive regulation of proteoglycan biosynthetic process

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of proteoglycan biosynthetic process

negative regulation of glycoprotein metabolic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of proteoglycan biosynthetic process

positive regulation of glycoprotein metabolic process [inference]

positive regulation of glycoprotein biosynthetic process [inference]

positive regulation of proteoglycan biosynthetic process

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of connective tissue growth factor production

regulation of connective tissue growth factor production [inference]

negative regulation of connective tissue growth factor production

positive regulation of gene expression

negative regulation of gene expression

negative regulation of cytokine production [inference]

negative regulation of connective tissue growth factor production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of glycoprotein biosynthetic process [inference]

positive regulation of proteoglycan biosynthetic process

positive regulation of gene expression

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of proteoglycan biosynthetic process

negative regulation of gene expression

negative regulation of cytokine production [inference]

negative regulation of connective tissue growth factor production

regulation of glycoprotein biosynthetic process [inference]

positive regulation of glycoprotein biosynthetic process [inference]

positive regulation of proteoglycan biosynthetic process

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of proteoglycan biosynthetic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of glycoprotein biosynthetic process [inference]

positive regulation of proteoglycan biosynthetic process

positive regulation of gene expression

positive regulation of protein metabolic process [inference]

positive regulation of glycoprotein metabolic process [inference]

positive regulation of glycoprotein biosynthetic process [inference]

positive regulation of proteoglycan biosynthetic process

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of proteoglycan biosynthetic process

negative regulation of gene expression

negative regulation of cytokine production [inference]

negative regulation of connective tissue growth factor production

negative regulation of protein metabolic process [inference]

negative regulation of glycoprotein metabolic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of proteoglycan biosynthetic process

regulation of protein metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of glycoprotein metabolic process [inference]

positive regulation of glycoprotein biosynthetic process [inference]

positive regulation of proteoglycan biosynthetic process

negative regulation of protein metabolic process [inference]

negative regulation of glycoprotein metabolic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of proteoglycan biosynthetic process

regulation of glycoprotein metabolic process [inference]

regulation of glycoprotein biosynthetic process [inference]

positive regulation of glycoprotein biosynthetic process [inference]

positive regulation of proteoglycan biosynthetic process

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of proteoglycan biosynthetic process

negative regulation of glycoprotein metabolic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of proteoglycan biosynthetic process

positive regulation of glycoprotein metabolic process [inference]

positive regulation of glycoprotein biosynthetic process [inference]

positive regulation of proteoglycan biosynthetic process

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of glycoprotein metabolic process [inference]

positive regulation of glycoprotein biosynthetic process [inference]

positive regulation of proteoglycan biosynthetic process

negative regulation of protein metabolic process [inference]

negative regulation of glycoprotein metabolic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of proteoglycan biosynthetic process

regulation of glycoprotein metabolic process [inference]

regulation of glycoprotein biosynthetic process [inference]

positive regulation of glycoprotein biosynthetic process [inference]

positive regulation of proteoglycan biosynthetic process

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of proteoglycan biosynthetic process

negative regulation of glycoprotein metabolic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of proteoglycan biosynthetic process

positive regulation of glycoprotein metabolic process [inference]

positive regulation of glycoprotein biosynthetic process [inference]

positive regulation of proteoglycan biosynthetic process

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of transforming growth factor beta receptor signaling pathway

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of transforming growth factor beta receptor signaling pathway

negative regulation of integrin-mediated signaling pathway

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of transforming growth factor beta receptor signaling pathway [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of transforming growth factor beta receptor signaling pathway

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of transforming growth factor beta receptor signaling pathway

regulation of integrin-mediated signaling pathway [inference]

negative regulation of integrin-mediated signaling pathway

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of transforming growth factor beta receptor signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of transforming growth factor beta receptor signaling pathway

negative regulation of integrin-mediated signaling pathway

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of glycoprotein biosynthetic process [inference]

positive regulation of proteoglycan biosynthetic process

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of glycoprotein biosynthetic process [inference]

positive regulation of proteoglycan biosynthetic process

positive regulation of gene expression

positive regulation of protein metabolic process [inference]

positive regulation of glycoprotein metabolic process [inference]

positive regulation of glycoprotein biosynthetic process [inference]

positive regulation of proteoglycan biosynthetic process

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of glycoprotein biosynthetic process [inference]

positive regulation of proteoglycan biosynthetic process

positive regulation of gene expression

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of glycoprotein metabolic process [inference]

positive regulation of glycoprotein biosynthetic process [inference]

positive regulation of proteoglycan biosynthetic process

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of transforming growth factor beta receptor signaling pathway

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of transforming growth factor beta receptor signaling pathway

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of glycoprotein biosynthetic process [inference]

positive regulation of proteoglycan biosynthetic process

positive regulation of gene expression

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of transforming growth factor beta receptor signaling pathway

positive regulation of cellular response to transforming growth factor beta stimulus [inference]

positive regulation of transforming growth factor beta receptor signaling pathway

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of proteoglycan biosynthetic process

negative regulation of gene expression

negative regulation of cytokine production [inference]

negative regulation of connective tissue growth factor production

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of proteoglycan biosynthetic process

negative regulation of gene expression

negative regulation of cytokine production [inference]

negative regulation of connective tissue growth factor production

negative regulation of protein metabolic process [inference]

negative regulation of glycoprotein metabolic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of proteoglycan biosynthetic process

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of proteoglycan biosynthetic process

negative regulation of gene expression

negative regulation of cytokine production [inference]

negative regulation of connective tissue growth factor production

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of glycoprotein metabolic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of proteoglycan biosynthetic process

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of transforming growth factor beta receptor signaling pathway

negative regulation of integrin-mediated signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of transforming growth factor beta receptor signaling pathway

negative regulation of integrin-mediated signaling pathway

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of proteoglycan biosynthetic process

negative regulation of gene expression

negative regulation of cytokine production [inference]

negative regulation of connective tissue growth factor production

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of transforming growth factor beta receptor signaling pathway

negative regulation of integrin-mediated signaling pathway

negative regulation of multicellular organismal process [inference]

negative regulation of cytokine production [inference]

negative regulation of connective tissue growth factor production

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of transforming growth factor beta receptor signaling pathway

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of transforming growth factor beta receptor signaling pathway

negative regulation of integrin-mediated signaling pathway

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of transforming growth factor beta receptor signaling pathway [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of transforming growth factor beta receptor signaling pathway

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of transforming growth factor beta receptor signaling pathway

regulation of integrin-mediated signaling pathway [inference]

negative regulation of integrin-mediated signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of transforming growth factor beta receptor signaling pathway

positive regulation of cellular response to transforming growth factor beta stimulus [inference]

positive regulation of transforming growth factor beta receptor signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of transforming growth factor beta receptor signaling pathway

negative regulation of integrin-mediated signaling pathway

regulation of cellular response to growth factor stimulus [inference]

regulation of cellular response to transforming growth factor beta stimulus [inference]

regulation of transforming growth factor beta receptor signaling pathway [inference]

positive regulation of cellular response to transforming growth factor beta stimulus [inference]

positive regulation of transforming growth factor beta receptor signaling pathway

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of transforming growth factor beta receptor signaling pathway

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of transforming growth factor beta receptor signaling pathway

negative regulation of integrin-mediated signaling pathway

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of transforming growth factor beta receptor signaling pathway [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of transforming growth factor beta receptor signaling pathway

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of transforming growth factor beta receptor signaling pathway

regulation of integrin-mediated signaling pathway [inference]

negative regulation of integrin-mediated signaling pathway

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of transforming growth factor beta receptor signaling pathway

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of transforming growth factor beta receptor signaling pathway

negative regulation of integrin-mediated signaling pathway

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of proteoglycan biosynthetic process

negative regulation of gene expression

negative regulation of cytokine production [inference]

negative regulation of connective tissue growth factor production

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of glycoprotein biosynthetic process [inference]

positive regulation of proteoglycan biosynthetic process

positive regulation of gene expression

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of connective tissue growth factor production

regulation of connective tissue growth factor production [inference]

negative regulation of connective tissue growth factor production

positive regulation of gene expression

negative regulation of gene expression

negative regulation of cytokine production [inference]

negative regulation of connective tissue growth factor production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of glycoprotein biosynthetic process [inference]

positive regulation of proteoglycan biosynthetic process

positive regulation of gene expression

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of proteoglycan biosynthetic process

negative regulation of gene expression

negative regulation of cytokine production [inference]

negative regulation of connective tissue growth factor production

regulation of glycoprotein biosynthetic process [inference]

positive regulation of glycoprotein biosynthetic process [inference]

positive regulation of proteoglycan biosynthetic process

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of proteoglycan biosynthetic process

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of proteoglycan biosynthetic process

negative regulation of gene expression

negative regulation of cytokine production [inference]

negative regulation of connective tissue growth factor production

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of glycoprotein biosynthetic process [inference]

positive regulation of proteoglycan biosynthetic process

positive regulation of gene expression

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of transforming growth factor beta receptor signaling pathway

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of glycoprotein biosynthetic process [inference]

positive regulation of proteoglycan biosynthetic process

positive regulation of gene expression

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of transforming growth factor beta receptor signaling pathway

negative regulation of integrin-mediated signaling pathway

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of glycoprotein biosynthetic process [inference]

negative regulation of proteoglycan biosynthetic process

negative regulation of gene expression

negative regulation of cytokine production [inference]

negative regulation of connective tissue growth factor production

regulation of cellular component organization [inference]

regulation of extracellular matrix organization

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of connective tissue growth factor production

regulation of connective tissue growth factor production [inference]

negative regulation of connective tissue growth factor production

negative regulation of multicellular organismal process [inference]

negative regulation of cytokine production [inference]

negative regulation of connective tissue growth factor production

Displaying **all 5** entries
GO Term	Evidence Code	PMID
cytosol	IDA
endomembrane system	IEA
plasma membrane	IDA RCA TAS	11592815 16550171
membrane	IBA NAS	11247674
perinuclear region of cytoplasm	IDA	16550171

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

perinuclear region of cytoplasm

Displaying **all 4** entries
GO Term	Evidence Code	PMID
carbohydrate:proton symporter activity		11247674
symporter activity	IBA
D-glucose transmembrane transporter activity	IBA IDA TAS	11592815
dehydroascorbic acid transmembrane transporter activity	IDA	27153185

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

organic anion transmembrane transporter activity [inference]

dehydroascorbic acid transmembrane transporter activity

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

proton transmembrane transporter activity [inference]

solute:proton symporter activity [inference]

carbohydrate:proton symporter activity

solute:monoatomic cation symporter activity [inference]

carbohydrate:monoatomic cation symporter activity [inference]

carbohydrate:proton symporter activity

solute:proton symporter activity [inference]

carbohydrate:proton symporter activity

active monoatomic ion transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

carbohydrate:monoatomic cation symporter activity [inference]

carbohydrate:proton symporter activity

solute:proton symporter activity [inference]

carbohydrate:proton symporter activity

carbohydrate transmembrane transporter activity [inference]

carbohydrate:monoatomic cation symporter activity [inference]

carbohydrate:proton symporter activity

sugar transmembrane transporter activity [inference]

monosaccharide transmembrane transporter activity [inference]

hexose transmembrane transporter activity [inference]

glucose transmembrane transporter activity [inference]

D-glucose transmembrane transporter activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

proton transmembrane transporter activity [inference]

solute:proton symporter activity [inference]

carbohydrate:proton symporter activity

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

symporter activity

solute:monoatomic cation symporter activity [inference]

carbohydrate:monoatomic cation symporter activity [inference]

carbohydrate:proton symporter activity

solute:proton symporter activity [inference]

carbohydrate:proton symporter activity

active monoatomic ion transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

carbohydrate:monoatomic cation symporter activity [inference]

carbohydrate:proton symporter activity

solute:proton symporter activity [inference]

carbohydrate:proton symporter activity

vitamin transmembrane transporter activity [inference]

dehydroascorbic acid transmembrane transporter activity

Gene Ontology information from NCBI Gene and UniProt.

Human Protein Atlas

ENSG00000197496

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

KEGG BRITE Database

Orthology

K08147

Name

MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 10

References

Disease

Disease Ontology

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DO ID	Disease Name	Source
DOID:6000	congestive heart failure	DisGeNET
DOID:65	connective tissue disease	DisGeNET
DOID:657	adenoma	DisGeNET
DOID:6612	leukocyte adhesion deficiency	DisGeNET
DOID:6713	cerebrovascular disease	DisGeNET
DOID:820	myocarditis	DisGeNET
DOID:8534	gastroesophageal reflux disease	DisGeNET DisGeNET
DOID:854	collagen disease	DisGeNET
DOID:8927	learning disability	DisGeNET
DOID:9306	mechanical strabismus	DisGeNET

The Human Phenotype Ontology

Displaying entries **71 - 80** of 95 in total

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HPO ID	HPO Term
HP:0003623	Neonatal onset
HP:0004209	Clinodactyly of the 5th finger
HP:0004415	Pulmonary artery stenosis
HP:0004942	Aortic aneurysm
HP:0004955	Generalized arterial tortuosity
HP:0005328	Progeroid facial appearance
HP:0005344	Abnormal carotid artery morphology
HP:0005743	Avascular necrosis of the capital femoral epiphysis
HP:0006543	Cardiorespiratory arrest
HP:0006687	Aortic tortuosity

Displaying **all 2** entries
Disease ID	Disease Name
OMIM:208050	arterial tortuosity syndrome
ORPHA:3342	arterial tortuosity syndrome

PubChem Disease

GHR Health Conditions

Arterial tortuosity syndrome

MedGen Diseases

Arterial tortuosity syndrome

OMIM Phenotypes

ARTERIAL TORTUOSITY SYNDROME; ATORS

KEGG Diseases

Arterial tortuosity syndrome

Gene-Disease-Co-Occurrences-in-Literature (PubChem)

Ortholog

Displaying entries **1 - 10** of 70 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Callorhinchus milii	103186264		CALMI34221
Latimeria chalumnae	102364983		LATCH10365
Danio rerio	560546	ZFIN:ZDB-GENE-080204-6	DANRE03179
Astyanax mexicanus	103042379		ASTMX05310
Ictalurus punctatus	108255251		ICTPU16406
Salmo salar	106565264		SALSA24493
Salmo trutta	115208344		SALTR34707
Gadus morhua	115542397		GADMO27705
Oreochromis niloticus	100710582		ORENI59894
Sparus aurata	115583513		SPAAU42212

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

KEGG BRITE Database

PubChem Disease

International Collaboration

Acknowledgements