calreticulin

Summary
Gene Symbol
  • CALR
Aliases
  • CRT
  • FLJ26680
  • RO
  • SSA
  • Sicca syndrome antigen A (autoantigen Ro; calreticulin)
  • autoantigen Ro
  • cC1qR
  • calregulin
Organism
Homo sapiens (human)
External Links
NCBI Gene
811
HGNC
1455
KEGG Gene ID
hsa:811
PubChem
811
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • Acetylation
  • Calcium
  • Chaperone
  • Cytoplasm
  • Cytoplasmic vesicle
  • Direct protein sequencing
  • Disulfide bond
  • Endoplasmic reticulum
  • Extracellular matrix
  • Glycoprotein
  • Hydroxylation
  • Lectin
  • Lysosome
  • Metal-binding
  • Reference proteome
  • Repeat
  • Sarcoplasmic reticulum
  • Signal
  • Zinc
Proteins
Displaying all 2 entries
UniProt Protein Name
P27797
  • CRP55
  • Calregulin
  • Endoplasmic reticulum resident protein 60
  • HACBP
  • grp60
V9HW88
Gene Ontology (GO)
Displaying entries 41 - 42 of 42 in total
GO Term Evidence Code PMID
response to estradiol
peptide antigen assembly with MHC class I protein complex
GO Hierarchy
GO Hierarchy
Human Protein Atlas
ENSG00000179218

soft tissue soft tissue blood blood blood blood blood blood blood blood blood blood blood blood blood blood lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node kidney kidney adrenal gland adrenal gland breast breast duodenum stomach small intestine colon rectum appendix esophagus eye eye salivary gland nasopharynx nasopharynx tongue tonsil tonsil tonsil hair skin adipose tissue adipose tissue adipose tissue spinal cord oral mucosa lung lung heart bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus liver pancreas thyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland spleen gallbladder ductus deferens ductus deferens seminal vesicle seminal vesicle seminal vesicle seminal vesicle testis testis epididymis epididymis brain smooth muscle urinary bladder prostate bone marrow skeletal muscle skeletal muscle skeletal muscle skeletal muscle skeletal muscle thymus thymus cartilage sole of foot sole of foot soft tissue blood blood blood blood blood blood blood blood blood blood blood blood lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lactating breast lactating breast kidney kidney adrenal gland adrenal gland duodenum stomach small intestine colon rectum appendix esophagus eye eye salivary gland salivary gland salivary gland salivary gland salivary gland salivary gland nasopharynx tongue tonsil tonsil hair skin adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue spinal cord oral mucosa lung lung heart bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus liver pancreas thyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland spleen gallbladder brain skeletal muscle skeletal muscle skeletal muscle skeletal muscle skeletal muscle thymus thymus smooth muscle urinary bladder vagina ovary ovary fallopian tube fallopian tube endometrium placenta cervix cervix bone marrow cartilage sole of foot sole of foot olfactory region cerebral cortex cerebellum medulla pons midbrain pituitary gland hypothalamus amygdala thalamus choroid plexus choroid plexus corpus callosum basal ganglia substantia nigra dorsal raphe dorsal raphe dorsal raphe dorsal raphe dorsal raphe dorsal raphe caudate hippocampus retina retina

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

KEGG BRITE Database
Orthology
K08057
Name
calreticulin
References
Disease
Disease Ontology
Displaying entries 11 - 20 of 410 in total
DO ID Disease Name Source
DOID:0050589 inflammatory bowel disease
DOID:0050632 oculocutaneous albinism
DOID:0050700 cardiomyopathy
DOID:0050731 vitamin B12 deficiency
DOID:0050745 diffuse large B-cell lymphoma
DOID:0050778 Meckel syndrome
DOID:0050800 cerebral creatine deficiency syndrome 1
DOID:0050819 obsolete Matthew-Wood syndrome
DOID:0050820 atrioventricular block
DOID:0050865 tongue squamous cell carcinoma
The Human Phenotype Ontology
Displaying entries 61 - 70 of 72 in total
HPO ID HPO Term
HP:0008148 Impaired epinephrine-induced platelet aggregation
HP:0008320 Impaired collagen-induced platelet aggregation
HP:0011134 Low-grade fever
HP:0011875 Abnormal platelet morphology
HP:0011974 Myelofibrosis
HP:0012143 Abnormal megakaryocyte morphology
HP:0012156 Hemophagocytosis
HP:0012378 Fatigue
HP:0100576 Amaurosis fugax
HP:0100659 Abnormal cerebral vascular morphology
Displaying all 5 entries
Disease ID Disease Name
ORPHA:824
  • primary myelofibrosis
OMIM:254450
  • primary myelofibrosis
ORPHA:3318
  • essential thrombocythemia
OMIM:187950
  • thrombocythemia 1
ORPHA:131
  • Budd-Chiari syndrome

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024