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subtilisin-like protease 1

Summary

Gene Symbol

PF3D7_0507500

Organism

Plasmodium falciparum 3D7

External Links

NCBI Gene: 812875
PubChem: 812875

Annotation

Keyword

3D-structure
Calcium
Disulfide bond
Glycoprotein
Metal-binding
Reference proteome
Secreted
Serine protease
Signal
Zymogen

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8I0V0	PfSUB1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
proteolysis	TAS	12764150
membrane protein ectodomain proteolysis
response to xenobiotic stimulus	IMP	33975947
protein processing
exit from host cell	IMP	18083098 29459732

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein processing

membrane protein proteolysis [inference]

membrane protein ectodomain proteolysis

protein maturation [inference]

protein processing

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein processing

membrane protein proteolysis [inference]

membrane protein ectodomain proteolysis

protein maturation [inference]

protein processing

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein processing

membrane protein proteolysis [inference]

membrane protein ectodomain proteolysis

protein maturation [inference]

protein processing

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein processing

membrane protein proteolysis [inference]

membrane protein ectodomain proteolysis

protein maturation [inference]

protein processing

biological process involved in interspecies interaction between organisms [inference]

biological process involved in symbiotic interaction [inference]

biological process involved in interaction with host [inference]

movement in host [inference]

exit from host cell

response to stimulus [inference]

response to chemical [inference]

response to xenobiotic stimulus

Displaying **all 5** entries
GO Term	Evidence Code	PMID
membrane
symbiont-containing vacuole	IDA	19214190
symbiont-containing vacuolar space
merozoite dense granule	IDA	9722575
exoneme	IDA	18083098

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

host cellular component [inference]

host cell part [inference]

symbiont-containing vacuolar space

host intracellular part [inference]

host cell cytoplasm part [inference]

symbiont-containing vacuole

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

merozoite dense granule

intracellular membrane-bounded organelle [inference]

exoneme

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

merozoite dense granule

extracellular membrane-bounded organelle [inference]

symbiont-containing vacuole

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

exoneme

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

merozoite dense granule

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

symbiont-containing vacuole

Displaying **all 3** entries
GO Term	Evidence Code	PMID
serine-type endopeptidase activity	TAS	9722575
serine-type peptidase activity	IDA	12764150
metal ion binding

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

endopeptidase activity [inference]

serine-type endopeptidase activity

serine-type peptidase activity

serine-type endopeptidase activity

serine hydrolase activity [inference]

serine-type peptidase activity

serine-type endopeptidase activity

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

endopeptidase activity [inference]

serine-type endopeptidase activity

serine-type peptidase activity

serine-type endopeptidase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

subtilisin

Functional Category

H: Coenzyme transport and metabolism
I: Lipid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
X: Mobilome: prophages, transposons

Displaying **all 4** entries
Gene Ontology
hydrolase activity
proteolysis
serine-type endopeptidase activity
serine-type peptidase activity

Displaying **all 7** entries
InterPro
Peptidase S8, subtilisin, Asp-active site
Peptidase S8, subtilisin, His-active site
Peptidase S8, subtilisin, Ser-active site
Peptidase S8, subtilisin-related
Peptidase S8/S53 domain superfamily
Peptidase S8/S53 domain
Subtilisin SUB1-like catalytic domain