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6-cysteine protein

Summary

Gene Symbol

PF3D7_1346800

Organism

Plasmodium falciparum 3D7

External Links

NCBI Gene: 814213
PubChem: 814213

Annotation

Keyword

Cell membrane
Disulfide bond
GPI-anchor
Malaria
Reference proteome
Repeat
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8IDN0

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
evasion of host immune response
modulation by symbiont of host cellular process	IMP	25552553
suppression of host innate immune response	IMP	23661646

GO Hierarchy

biological process

biological process involved in interspecies interaction between organisms [inference]

modulation of process of another organism [inference]

modulation by symbiont of host process [inference]

modulation by symbiont of host cellular process

symbiont-mediated perturbation of host defense response [inference]

symbiont-mediated perturbation of host immune response [inference]

evasion of host immune response

perturbation of host innate immune response [inference]

suppression of host innate immune response

suppression by symbiont of host immune response [inference]

suppression of host innate immune response

biological process involved in symbiotic interaction [inference]

biological process involved in interaction with host [inference]

modulation by symbiont of host process [inference]

modulation by symbiont of host cellular process

symbiont-mediated perturbation of host defense response [inference]

symbiont-mediated perturbation of host immune response [inference]

evasion of host immune response

perturbation of host innate immune response [inference]

suppression of host innate immune response

suppression by symbiont of host immune response [inference]

suppression of host innate immune response

response to host [inference]

response to host defenses [inference]

perturbation of host defenses by symbiont [inference]

suppression of host defenses by symbiont [inference]

suppression of host innate immune response

symbiont-mediated perturbation of host defense response [inference]

symbiont-mediated perturbation of host immune response [inference]

evasion of host immune response

perturbation of host innate immune response [inference]

suppression of host innate immune response

suppression by symbiont of host immune response [inference]

suppression of host innate immune response

response to host immune response [inference]

symbiont-mediated perturbation of host immune response [inference]

evasion of host immune response

perturbation of host innate immune response [inference]

suppression of host innate immune response

suppression by symbiont of host immune response [inference]

suppression of host innate immune response

response to other organism [inference]

response to defenses of other organism [inference]

response to host defenses [inference]

perturbation of host defenses by symbiont [inference]

suppression of host defenses by symbiont [inference]

suppression of host innate immune response

symbiont-mediated perturbation of host defense response [inference]

symbiont-mediated perturbation of host immune response [inference]

evasion of host immune response

perturbation of host innate immune response [inference]

suppression of host innate immune response

suppression by symbiont of host immune response [inference]

suppression of host innate immune response

response to host immune response [inference]

symbiont-mediated perturbation of host immune response [inference]

evasion of host immune response

perturbation of host innate immune response [inference]

suppression of host innate immune response

suppression by symbiont of host immune response [inference]

suppression of host innate immune response

response to host [inference]

response to host defenses [inference]

perturbation of host defenses by symbiont [inference]

suppression of host defenses by symbiont [inference]

suppression of host innate immune response

symbiont-mediated perturbation of host defense response [inference]

symbiont-mediated perturbation of host immune response [inference]

evasion of host immune response

perturbation of host innate immune response [inference]

suppression of host innate immune response

suppression by symbiont of host immune response [inference]

suppression of host innate immune response

response to host immune response [inference]

symbiont-mediated perturbation of host immune response [inference]

evasion of host immune response

perturbation of host innate immune response [inference]

suppression of host innate immune response

suppression by symbiont of host immune response [inference]

suppression of host innate immune response

response to stimulus [inference]

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to defenses of other organism [inference]

response to host defenses [inference]

perturbation of host defenses by symbiont [inference]

suppression of host defenses by symbiont [inference]

suppression of host innate immune response

symbiont-mediated perturbation of host defense response [inference]

symbiont-mediated perturbation of host immune response [inference]

evasion of host immune response

perturbation of host innate immune response [inference]

suppression of host innate immune response

suppression by symbiont of host immune response [inference]

suppression of host innate immune response

response to host immune response [inference]

symbiont-mediated perturbation of host immune response [inference]

evasion of host immune response

perturbation of host innate immune response [inference]

suppression of host innate immune response

suppression by symbiont of host immune response [inference]

suppression of host innate immune response

response to host [inference]

response to host defenses [inference]

perturbation of host defenses by symbiont [inference]

suppression of host defenses by symbiont [inference]

suppression of host innate immune response

symbiont-mediated perturbation of host defense response [inference]

symbiont-mediated perturbation of host immune response [inference]

evasion of host immune response

perturbation of host innate immune response [inference]

suppression of host innate immune response

suppression by symbiont of host immune response [inference]

suppression of host innate immune response

response to host immune response [inference]

symbiont-mediated perturbation of host immune response [inference]

evasion of host immune response

perturbation of host innate immune response [inference]

suppression of host innate immune response

suppression by symbiont of host immune response [inference]

suppression of host innate immune response

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to defenses of other organism [inference]

response to host defenses [inference]

perturbation of host defenses by symbiont [inference]

suppression of host defenses by symbiont [inference]

suppression of host innate immune response

symbiont-mediated perturbation of host defense response [inference]

symbiont-mediated perturbation of host immune response [inference]

evasion of host immune response

perturbation of host innate immune response [inference]

suppression of host innate immune response

suppression by symbiont of host immune response [inference]

suppression of host innate immune response

response to host immune response [inference]

symbiont-mediated perturbation of host immune response [inference]

evasion of host immune response

perturbation of host innate immune response [inference]

suppression of host innate immune response

suppression by symbiont of host immune response [inference]

suppression of host innate immune response

response to host [inference]

response to host defenses [inference]

perturbation of host defenses by symbiont [inference]

suppression of host defenses by symbiont [inference]

suppression of host innate immune response

symbiont-mediated perturbation of host defense response [inference]

symbiont-mediated perturbation of host immune response [inference]

evasion of host immune response

perturbation of host innate immune response [inference]

suppression of host innate immune response

suppression by symbiont of host immune response [inference]

suppression of host innate immune response

response to host immune response [inference]

symbiont-mediated perturbation of host immune response [inference]

evasion of host immune response

perturbation of host innate immune response [inference]

suppression of host innate immune response

suppression by symbiont of host immune response [inference]

suppression of host innate immune response

Displaying **all 4** entries
GO Term	Evidence Code	PMID
plasma membrane	RCA	16603573
cell surface	ISO	28729672
cell surface	IDA	16824624
side of membrane

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cell surface

membrane [inference]

plasma membrane

side of membrane

Displaying 1 entry
GO Term	Evidence Code	PMID
host cell surface receptor binding	IPI	31969456

GO Hierarchy

molecular function

binding [inference]

host cell surface binding [inference]

host cell surface receptor binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level: Eukaryota
Group Name: 6-cysteine protein

Displaying **all 2** entries
InterPro
6-Cysteine (6-Cys) domain superfamily
6-Cysteine (6-Cys) domain

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Last updated: December 8, 2025

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