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Endoribonuclease/protein kinase IRE1-like protein

Summary

Gene Symbol

IRE1A

Organism

Arabidopsis thaliana (thale cress)

External Links

NCBI Gene: 816258
PubChem: 816258

Annotation

Keyword

ATP-binding
Disulfide bond
Endoplasmic reticulum
Glycoprotein
Hydrolase
Immunity
Magnesium
Metal-binding
Multifunctional enzyme
Reference proteome
Serine/threonine-protein kinase
Signal
Transcription regulation
Transmembrane helix
Unfolded protein response
mRNA splicing

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9C5S2	Endoplasmic reticulum-to-nucleus signaling 1-2 Inositol-requiring protein 1-2 Serine/threonine-protein kinase/endoribonuclease IRE1-2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
immune system process
RNA processing	IDA	34354728
mRNA processing
RNA splicing	IMP	22355548
response to salicylic acid	IMP	22359644

GO Hierarchy

biological process

immune system process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing

mRNA metabolic process [inference]

mRNA processing

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation [inference]

protein autophosphorylation

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing

mRNA metabolic process [inference]

mRNA processing

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation [inference]

protein autophosphorylation

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing

mRNA metabolic process [inference]

mRNA processing

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing

mRNA metabolic process [inference]

mRNA processing

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing

mRNA metabolic process [inference]

mRNA processing

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation [inference]

protein autophosphorylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation [inference]

protein autophosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein phosphorylation [inference]

protein autophosphorylation

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing

mRNA metabolic process [inference]

mRNA processing

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing

mRNA metabolic process [inference]

mRNA processing

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation [inference]

protein autophosphorylation

cellular process [inference]

signal transduction [inference]

endoplasmic reticulum unfolded protein response

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing

mRNA metabolic process [inference]

mRNA processing

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation [inference]

protein autophosphorylation

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing

mRNA metabolic process [inference]

mRNA processing

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing

mRNA metabolic process [inference]

mRNA processing

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress

endoplasmic reticulum unfolded protein response

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium

defense response to other organism [inference]

defense response to bacterium

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

defense response to bacterium

cellular response to stress [inference]

response to endoplasmic reticulum stress

endoplasmic reticulum unfolded protein response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium

defense response to other organism [inference]

defense response to bacterium

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium

defense response to other organism [inference]

defense response to bacterium

response to chemical [inference]

response to organic substance [inference]

response to organic cyclic compound [inference]

response to salicylic acid

response to oxygen-containing compound [inference]

response to salicylic acid

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress

endoplasmic reticulum unfolded protein response

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

endoplasmic reticulum unfolded protein response

Displaying **all 4** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum	IDA	11706177
chloroplast	ISM
extrinsic component of endoplasmic reticulum membrane
secretory vesicle	HDA	25293756

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extrinsic component of membrane [inference]

extrinsic component of organelle membrane [inference]

extrinsic component of endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

plastid [inference]

chloroplast

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

plastid [inference]

chloroplast

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
RNA endonuclease activity	IMP	11706177
protein binding	IPI	29616060
ATP binding
histone H2AS1 kinase activity
metal ion binding

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity [inference]

histone H2AS1 kinase activity

histone kinase activity [inference]

histone H2A kinase activity [inference]

histone H2AS1 kinase activity

protein serine kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity [inference]

histone H2AS1 kinase activity

histone kinase activity [inference]

histone H2A kinase activity [inference]

histone H2AS1 kinase activity

protein serine kinase activity

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

nuclease activity [inference]

endonuclease activity [inference]

RNA endonuclease activity

RNA nuclease activity [inference]

RNA endonuclease activity

catalytic activity, acting on a protein [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity [inference]

histone H2AS1 kinase activity

histone kinase activity [inference]

histone H2A kinase activity [inference]

histone H2AS1 kinase activity

protein serine kinase activity

histone modifying activity [inference]

histone kinase activity [inference]

histone H2A kinase activity [inference]

histone H2AS1 kinase activity

catalytic activity, acting on a nucleic acid [inference]

catalytic activity, acting on RNA [inference]

RNA nuclease activity [inference]

RNA endonuclease activity

binding [inference]

protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

cation binding [inference]

metal ion binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP011274
Gene Name: serine/threonine-protein kinase/endoribonuclease IRE1a

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Tools

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Guidelines

Summary

External Links

Annotation

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements