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Guidelines

MIRAGE

alanyl aminopeptidase, membrane

Summary

Gene Symbol

Anpep

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

81641

PubChem

81641

Alliance of Genome Resources

RGD:2991

Annotation

Keyword

Aminopeptidase
Angiogenesis
Cell membrane
Developmental protein
Differentiation
Direct protein sequencing
Disulfide bond
Glycoprotein
Metal-binding
Metalloprotease
Phosphoprotein
Reference proteome
Signal-anchor
Sulfation
Transmembrane helix
Zinc

Proteins

Displaying **all 3** entries
UniProt	Protein Name
A6JC72
P15684	Alanyl aminopeptidase Aminopeptidase M Kidney Zn peptidase Microsomal aminopeptidase
G3V7W7

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
angiogenesis	IEA
angiotensin maturation	ISO
angiotensin maturation	IEA
proteolysis	IBA
proteolysis	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

amide metabolic process [inference]

peptide metabolic process [inference]

peptide hormone processing [inference]

angiotensin maturation

peptide catabolic process

organonitrogen compound metabolic process [inference]

peptide metabolic process [inference]

peptide hormone processing [inference]

angiotensin maturation

peptide catabolic process

protein metabolic process [inference]

protein processing

signaling receptor ligand precursor processing [inference]

peptide hormone processing [inference]

angiotensin maturation

protein maturation [inference]

protein processing

signaling receptor ligand precursor processing [inference]

peptide hormone processing [inference]

angiotensin maturation

organonitrogen compound catabolic process [inference]

peptide catabolic process

catabolic process [inference]

cellular catabolic process [inference]

peptide catabolic process

organic substance catabolic process [inference]

organonitrogen compound catabolic process [inference]

peptide catabolic process

hormone metabolic process [inference]

peptide hormone processing [inference]

angiotensin maturation

cellular metabolic process [inference]

cellular catabolic process [inference]

peptide catabolic process

primary metabolic process [inference]

protein metabolic process [inference]

protein processing

signaling receptor ligand precursor processing [inference]

peptide hormone processing [inference]

angiotensin maturation

protein maturation [inference]

protein processing

signaling receptor ligand precursor processing [inference]

peptide hormone processing [inference]

angiotensin maturation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein processing

signaling receptor ligand precursor processing [inference]

peptide hormone processing [inference]

angiotensin maturation

protein maturation [inference]

protein processing

signaling receptor ligand precursor processing [inference]

peptide hormone processing [inference]

angiotensin maturation

organonitrogen compound metabolic process [inference]

peptide metabolic process [inference]

peptide hormone processing [inference]

angiotensin maturation

peptide catabolic process

protein metabolic process [inference]

protein processing

signaling receptor ligand precursor processing [inference]

peptide hormone processing [inference]

angiotensin maturation

protein maturation [inference]

protein processing

signaling receptor ligand precursor processing [inference]

peptide hormone processing [inference]

angiotensin maturation

organonitrogen compound catabolic process [inference]

peptide catabolic process

organic substance catabolic process [inference]

organonitrogen compound catabolic process [inference]

peptide catabolic process

cellular process [inference]

cellular metabolic process [inference]

cellular catabolic process [inference]

peptide catabolic process

cellular developmental process [inference]

cell differentiation

developmental process [inference]

anatomical structure formation involved in morphogenesis [inference]

angiogenesis

anatomical structure development [inference]

tissue development [inference]

epithelium development [inference]

renal tubule development [inference]

nephron tubule development [inference]

proximal tubule development [inference]

metanephric proximal tubule development

metanephric nephron tubule development [inference]

metanephric proximal tubule development

kidney epithelium development [inference]

nephron epithelium development [inference]

nephron tubule development [inference]

proximal tubule development [inference]

metanephric proximal tubule development

metanephric nephron tubule development [inference]

metanephric proximal tubule development

metanephric nephron epithelium development [inference]

metanephric nephron tubule development [inference]

metanephric proximal tubule development

metanephric epithelium development [inference]

metanephric tubule development [inference]

metanephric nephron tubule development [inference]

metanephric proximal tubule development

metanephric nephron epithelium development [inference]

metanephric nephron tubule development [inference]

metanephric proximal tubule development

tube development [inference]

renal tubule development [inference]

nephron tubule development [inference]

proximal tubule development [inference]

metanephric proximal tubule development

metanephric nephron tubule development [inference]

metanephric proximal tubule development

metanephric tubule development [inference]

metanephric nephron tubule development [inference]

metanephric proximal tubule development

cellular developmental process [inference]

cell differentiation

biological regulation [inference]

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone metabolic process [inference]

peptide hormone processing [inference]

angiotensin maturation

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	PMID
extracellular space	ISO
extracellular space	IBA
cytoplasm	IBA
endoplasmic reticulum-Golgi intermediate compartment	ISO
endoplasmic reticulum-Golgi intermediate compartment	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

cell projection membrane [inference]

brush border membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum-Golgi intermediate compartment

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum-Golgi intermediate compartment

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

side of membrane [inference]

external side of plasma membrane

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
aminopeptidase activity	IDA	16537183 16619500
aminopeptidase activity	IEA
metallopeptidase activity	ISO
metallopeptidase activity	IEA
zinc ion binding	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

metallopeptidase activity

metalloexopeptidase activity [inference]

metalloaminopeptidase activity

exopeptidase activity [inference]

aminopeptidase activity

metalloaminopeptidase activity

metalloexopeptidase activity [inference]

metalloaminopeptidase activity

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

metallopeptidase activity

metalloexopeptidase activity [inference]

metalloaminopeptidase activity

exopeptidase activity [inference]

aminopeptidase activity

metalloaminopeptidase activity

metalloexopeptidase activity [inference]

metalloaminopeptidase activity

binding [inference]

amide binding [inference]

peptide binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

Gene Ontology information from NCBI Gene and UniProt.

Alliance of Genome Resources

Expression

Displaying 1 entry
Location	References
brush border membrane	PMID:12110004

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.5.0

Last updated: April 6, 2026