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A-kinase anchoring protein 1

Summary

Gene Symbol

AKAP1

Organism

Homo sapiens (human)

External Links

NCBI Gene

8165

PubChem

8165

Alliance of Genome Resources

HGNC:367

Annotation

Keyword

Alternative splicing
Kinase
Mitochondrion outer membrane
Phosphoprotein
RNA-binding
Reference proteome
Transit peptide
Transmembrane
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
A0A140VK05
Q92667	A-kinase anchor protein 149 kDa Dual specificity A-kinase-anchoring protein 1 Protein kinase A-anchoring protein 1 Spermatid A-kinase anchor protein 84
B4DN86

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
apoptotic process	ISS
antiviral innate immune response	IMP	31522117

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

innate immune response [inference]

antiviral innate immune response

cellular process [inference]

cell death [inference]

programmed cell death [inference]

apoptotic process

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to virus [inference]

defense response to virus [inference]

antiviral innate immune response

defense response to other organism [inference]

innate immune response [inference]

antiviral innate immune response

defense response to symbiont [inference]

defense response to virus [inference]

antiviral innate immune response

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

innate immune response [inference]

antiviral innate immune response

defense response to symbiont [inference]

defense response to virus [inference]

antiviral innate immune response

immune response [inference]

innate immune response [inference]

antiviral innate immune response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to virus [inference]

defense response to virus [inference]

antiviral innate immune response

defense response to other organism [inference]

innate immune response [inference]

antiviral innate immune response

defense response to symbiont [inference]

defense response to virus [inference]

antiviral innate immune response

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to virus [inference]

defense response to virus [inference]

antiviral innate immune response

defense response to other organism [inference]

innate immune response [inference]

antiviral innate immune response

defense response to symbiont [inference]

defense response to virus [inference]

antiviral innate immune response

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
mitochondrion	IDA
mitochondrion	IBA
mitochondrion	HTP	34800366
mitochondrial outer membrane	IEA
cytosol	TAS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

membrane

outer membrane [inference]

organelle outer membrane [inference]

mitochondrial outer membrane

organelle membrane [inference]

mitochondrial membrane [inference]

mitochondrial outer membrane

bounding membrane of organelle [inference]

organelle outer membrane [inference]

mitochondrial outer membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying **all 4** entries
GO Term	Evidence Code	PMID
RNA binding	HDA	22658674 22681889
protein binding	IPI	12223483 16642035 24083380 24981860 26496610 31522117 33961781
protein kinase A regulatory subunit binding	IBA
protein kinase A regulatory subunit binding	IPI	17911601

GO Hierarchy

molecular function

binding [inference]

protein binding

protein kinase A binding [inference]

protein kinase A regulatory subunit binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

a kinase anchor protein

Functional Category

L: Replication, recombination and repair
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
protein kinase A regulatory subunit binding

Displaying **all 7** entries
InterPro
A-kinase anchor protein 1, Tudor domain
A-kinase anchor protein 1, type I K homology domain
K Homology domain, type 1 superfamily
K Homology domain, type 1
K Homology domain
SNase-like, OB-fold superfamily
Tudor domain

Ortholog

Displaying entries **1 - 10** of 48 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus laevis	8165	Xenbase:XB-GENE-17340699
Mus musculus	11640	ZFIN:ZDB-GENE-030131-6844	MOUSE06588
Rattus norvegicus	114124	ZFIN:ZDB-GENE-030131-6844	RATNO01332
Pan troglodytes	455150		PANTR14985
Canis lupus familiaris	480567		CANLF18932
Bos taurus	532072		BOVIN12110
Macaca mulatta	708500		MACMU15230
Ornithorhynchus anatinus	100074798		ORNAN09388
Oryctolagus cuniculus	100357677		RABIT07537
Callithrix jacchus	100391330		CALJA34324