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MIRAGE
matrix metallopeptidase 9
Summary
- Gene Symbol
-
- Mmp9
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Calcium
- Collagen degradation
- Disulfide bond
- Extracellular matrix
- Glycoprotein
- Metal-binding
- Metalloprotease
- Reference proteome
- Repeat
- Signal
- Zinc
- Zymogen
- Proteins
| UniProt | Protein Name |
|---|---|
| P50282 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| skeletal system development | ||
| skeletal system development | ||
| ossification | ||
| response to hypoxia | ||
| kidney development |
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| extracellular space | ||
| extracellular space | ||
| extracellular space | ||
| extracellular space |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| fibronectin binding | ||
| endopeptidase activity | ||
| metalloendopeptidase activity | ||
| metalloendopeptidase activity | ||
| metalloendopeptidase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- metallopeptidase
- Functional Category
-
- M: Cell wall/membrane/envelope biogenesis
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| collagen catabolic process |
| extracellular matrix organization |
| hydrolase activity |
| metal ion binding |
| metalloendopeptidase activity |
| metallopeptidase activity |
| proteolysis |
| zinc ion binding |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050851 | glomerulosclerosis | |
| DOID:1073 | renal hypertension | |
| DOID:10941 | intracranial aneurysm | |
| DOID:224 | transient cerebral ischemia | |
| DOID:2316 | brain ischemia | |
| DOID:2349 | arteriosclerosis | |
| DOID:5844 | myocardial infarction | |
| DOID:6000 | congestive heart failure | |
| DOID:6432 | pulmonary hypertension | |
| DOID:7693 | abdominal aortic aneurysm |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 179991 | Xenbase:XB-GENE-876295 | ||
| 180351 | ZFIN:ZDB-GENE-040426-2132 | ||
| 282871 | BOVIN05389 | ||
| 403885 | CANLF09614 | ||
| 406397 | DANRE43482 | ||
| 458294 | PANTR25021 | ||
| 653023 | TAKRU36123 | ||
| 654325 | PIGXX11873 | ||
| 708084 | MACMU01682 | ||
| 100008993 | RABIT14858 |
