GlyCosmos Portal

Submissions

secretin receptor

Summary

Gene Symbol

Sctr

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

81779

PubChem

81779

Alliance of Genome Resources

RGD:621342

Annotation

Keyword

Cell membrane
G-protein coupled receptor
Glycoprotein
Phosphoprotein
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P23811

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 12 in total

1

2

3

Next ›

Last »
GO Term	Evidence Code	PMID
regulation of appetite	ISO ISS
intracellular water homeostasis	ISO ISS
cell surface receptor signaling pathway	IEA
renal water absorption	ISO
response to nutrient levels	ISO ISS

GO Hierarchy

biological process

metabolic process [inference]

adaptive thermogenesis [inference]

diet induced thermogenesis

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway

adenylate cyclase-activating G protein-coupled receptor signaling pathway

cellular component organization or biogenesis [inference]

cellular component organization [inference]

regulation of cellular component size [inference]

regulation of cell size [inference]

cell volume homeostasis [inference]

intracellular water homeostasis

multicellular organismal process [inference]

system process [inference]

renal system process [inference]

renal water transport [inference]

renal water absorption

renal absorption [inference]

renal water absorption

homeostatic process [inference]

cellular homeostasis [inference]

cell volume homeostasis [inference]

intracellular water homeostasis

intracellular chemical homeostasis [inference]

intracellular water homeostasis

chemical homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular water homeostasis

response to stimulus [inference]

response to external stimulus [inference]

response to extracellular stimulus [inference]

response to nutrient levels

localization [inference]

establishment of localization [inference]

transport [inference]

fluid transport [inference]

water transport [inference]

renal water transport [inference]

renal water absorption

organic substance transport [inference]

water transport [inference]

renal water transport [inference]

renal water absorption

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of lipid catabolic process

positive regulation of lipid metabolic process [inference]

positive regulation of lipid catabolic process

regulation of catabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of lipid catabolic process

regulation of lipid catabolic process [inference]

positive regulation of lipid catabolic process

regulation of primary metabolic process [inference]

regulation of lipid metabolic process [inference]

positive regulation of lipid metabolic process [inference]

positive regulation of lipid catabolic process

regulation of lipid catabolic process [inference]

positive regulation of lipid catabolic process

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of cAMP-mediated signaling

regulation of intracellular signal transduction [inference]

regulation of cAMP-mediated signaling [inference]

positive regulation of cAMP-mediated signaling

positive regulation of intracellular signal transduction [inference]

positive regulation of cAMP-mediated signaling

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of cAMP-mediated signaling

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic plasticity

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of lipid catabolic process

positive regulation of lipid metabolic process [inference]

positive regulation of lipid catabolic process

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of cAMP-mediated signaling

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of cAMP-mediated signaling

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of cAMP-mediated signaling

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of cAMP-mediated signaling

regulation of intracellular signal transduction [inference]

regulation of cAMP-mediated signaling [inference]

positive regulation of cAMP-mediated signaling

positive regulation of intracellular signal transduction [inference]

positive regulation of cAMP-mediated signaling

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of cAMP-mediated signaling

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway

adenylate cyclase-activating G protein-coupled receptor signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of cAMP-mediated signaling

regulation of intracellular signal transduction [inference]

regulation of cAMP-mediated signaling [inference]

positive regulation of cAMP-mediated signaling

positive regulation of intracellular signal transduction [inference]

positive regulation of cAMP-mediated signaling

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of cAMP-mediated signaling

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic plasticity

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of cAMP-mediated signaling

regulation of biological quality [inference]

regulation of anatomical structure size [inference]

regulation of cellular component size [inference]

regulation of cell size [inference]

cell volume homeostasis [inference]

intracellular water homeostasis

Displaying **all 2** entries
GO Term	Evidence Code	PMID
plasma membrane	IBA IEA
cytoplasmic microtubule	IEA ISO ISS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

microtubule [inference]

cytoplasmic microtubule

Displaying **all 5** entries
GO Term	Evidence Code	PMID
peptide hormone binding	IBA IEA ISO
G protein-coupled peptide receptor activity	IBA
secretin receptor activity	IBA IDA IEA ISO	1646711
G protein-coupled receptor activity	IEA
peptide binding	IDA IPI	12403838 1646711

GO Hierarchy

molecular function

binding [inference]

amide binding [inference]

peptide binding

peptide hormone binding

hormone binding [inference]

peptide hormone binding

molecular transducer activity [inference]

signaling receptor activity [inference]

peptide receptor activity [inference]

G protein-coupled peptide receptor activity

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

secretin receptor

Functional Category

C: Energy production and conversion
H: Coenzyme transport and metabolism
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 5** entries
Gene Ontology
G protein-coupled peptide receptor activity
adenylate cyclase-modulating G protein-coupled receptor signaling pathway
cell surface receptor signaling pathway
peptide hormone binding
secretin receptor activity

Displaying **all 7** entries
InterPro
GPCR family 2, extracellular hormone receptor domain superfamily
GPCR, family 2, extracellular hormone receptor domain
GPCR, family 2, secretin receptor
GPCR, family 2, secretin-like, conserved site
GPCR, family 2, secretin-like
GPCR, family 2-like, 7TM
Secretin receptor, 7TM

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:1574	alcohol use disorder	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 84 in total

1

2

3

4

5

…

Next ›

Last »
Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	6344		HGNC:10608	HUMAN64511
Mus musculus	319229	10090_1:0002bc	MGI:2441720	MOUSE27885
Pan troglodytes	459576			PANTR28545
Canis lupus familiaris	483883			CANLF06349
Macaca mulatta	695182			MACMU06311
Monodelphis domestica	100013364			MONDO25289
Taeniopygia guttata	100232013			TAEGU27815
Callithrix jacchus	100403202			CALJA37837
Pongo abelii	100436480			PONAB23850
Sus scrofa	100521045			PIGXX08971