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MIRAGE
ADAM metallopeptidase with thrombospondin type 1 motif 10
Summary
- Gene Symbol
-
- ADAMTS10
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Alternative splicing
- Calcium
- Cleavage on pair of basic residues
- Disease variant
- Disulfide bond
- Dwarfism
- Extracellular matrix
- Glycoprotein
- Integrin
- Metal-binding
- Metalloprotease
- Reference proteome
- Repeat
- Secreted
- Signal
- Zinc
- Zymogen
- Proteins
| UniProt | Protein Name |
|---|---|
| Q6ZN14 |
|
| Q9H324 |
|
| Q59FE5 |
|
| A0A0A0MQW6 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| proteolysis | ||
| extracellular matrix organization |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| microfibril | ||
| extracellular region | ||
| extracellular matrix | ||
| collagen-containing extracellular matrix |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| metalloendopeptidase activity | ||
| protein binding | ||
| metal ion binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- thrombospondin
- Functional Category
-
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| extracellular matrix organization |
| hydrolase activity |
| metal ion binding |
| metalloendopeptidase activity |
| metallopeptidase activity |
| proteolysis |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050475 | Weill-Marchesani syndrome |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 9719 | FB:FBgn0086408 | ||
| 11174 | FB:FBgn0086408 | ||
| 77794 | FB:FBgn0086408 | ||
| 81794 | Xenbase:XB-GENE-961723 | ||
| 170690 | FB:FBgn0086408 | ||
| 181022 | FB:FBgn0086408 | ||
| 181412 | FB:FBgn0086408 | ||
| 224697 | Xenbase:XB-GENE-961723 | MOUSE22973 | |
| 271127 | FB:FBgn0086408 | ||
| 314655 | RATNO37481 |
