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MIRAGE
Inositol phosphorylceramide synthase 2

Summary
Gene Symbol
  • AtIPCS2
Organism
Arabidopsis thaliana (thale cress)
NCBI Gene
818371
PubChem
818371
Annotation
Keyword
  • Golgi apparatus
  • Lipid biosynthesis
  • Plant defense
  • Reference proteome
  • Sphingolipid metabolism
  • Transferase
  • Transmembrane helix
Proteins
Displaying all 2 entries
UniProt Protein Name
A0A178VV03
Q9SH93
  • Inositol-phosphorylceramide synthase 2
  • Protein ENHANCING RPW8-MEDIATED HR-LIKE CELL DEATH 1
  • Sphingolipid synthase 2
Annotation information from UniProt.
Gene Ontology (GO)
Displaying all 2 entries
GO Term Evidence Code PMID
defense response
sphingolipid biosynthetic process
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
Phosphatidylinositol:ceramide inositolphosphotransferase
Functional Category
  • K: Transcription
  • L: Replication, recombination and repair
  • T: Signal transduction mechanisms
Displaying all 7 entries
Gene Ontology
ceramide biosynthetic process
ceramide cholinephosphotransferase activity
inositol phosphoceramide synthase activity
phosphotransferase activity, for other substituted phosphate groups
sphingolipid metabolic process
sphingomyelin synthase activity
transferase activity
Displaying all 2 entries
InterPro
Sphingomyelin synthase-like domain
Sphingomyelin synthase-like
Rhea

RHEA:64536

an N-(2R-hydroxy-very-long-chain fatty acyl)-(R)-4-hydroxysphingoid base + a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)
a 1D-myo-inositol-1-phospho-N-[(R)-2-hydroxy-very-long-chain fatty acyl]-(R)-4-hydroxysphingoid base + a 1,2-diacyl-sn-glycerol
Enzyme
PMID
LIPID MAPS Gene / Proteome Database
LMPD ID
LMP010822
Gene Name
inositol phosphorylceramide synthase 2
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025