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Guidelines

MIRAGE

N-acetyl-l-glutamate kinase

Summary

Gene Symbol

NAGK

Organism

Arabidopsis thaliana (thale cress)

External Links

NCBI Gene: 824923
KEGG Gene ID: ath:AT3G57560
PubChem: 824923

Annotation

Keyword

3D-structure
ATP-binding
Acetylation
Arginine biosynthesis
Chloroplast
Direct protein sequencing
Kinase
Reference proteome
Transit peptide

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9SCL7	N-acetyl-L-glutamate 5-phosphotransferase NAG kinase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
arginine biosynthetic process via ornithine	TAS	16377628

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process [inference]

arginine biosynthetic process via ornithine

alpha-amino acid metabolic process [inference]

ornithine metabolic process [inference]

arginine biosynthetic process via ornithine

glutamine family amino acid metabolic process [inference]

arginine metabolic process [inference]

arginine biosynthetic process [inference]

arginine biosynthetic process via ornithine

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process [inference]

arginine biosynthetic process via ornithine

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process [inference]

arginine biosynthetic process via ornithine

organonitrogen compound biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process [inference]

arginine biosynthetic process via ornithine

biosynthetic process [inference]

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process [inference]

arginine biosynthetic process via ornithine

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process [inference]

arginine biosynthetic process via ornithine

organic substance biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process [inference]

arginine biosynthetic process via ornithine

organonitrogen compound biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process [inference]

arginine biosynthetic process via ornithine

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process [inference]

arginine biosynthetic process via ornithine

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process [inference]

arginine biosynthetic process via ornithine

alpha-amino acid metabolic process [inference]

ornithine metabolic process [inference]

arginine biosynthetic process via ornithine

glutamine family amino acid metabolic process [inference]

arginine metabolic process [inference]

arginine biosynthetic process [inference]

arginine biosynthetic process via ornithine

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process [inference]

arginine biosynthetic process via ornithine

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process [inference]

arginine biosynthetic process via ornithine

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process [inference]

arginine biosynthetic process via ornithine

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process [inference]

arginine biosynthetic process via ornithine

primary metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process [inference]

arginine biosynthetic process via ornithine

alpha-amino acid metabolic process [inference]

ornithine metabolic process [inference]

arginine biosynthetic process via ornithine

glutamine family amino acid metabolic process [inference]

arginine metabolic process [inference]

arginine biosynthetic process [inference]

arginine biosynthetic process via ornithine

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process [inference]

arginine biosynthetic process via ornithine

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process [inference]

arginine biosynthetic process via ornithine

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process [inference]

arginine biosynthetic process via ornithine

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process [inference]

arginine biosynthetic process via ornithine

alpha-amino acid metabolic process [inference]

ornithine metabolic process [inference]

arginine biosynthetic process via ornithine

glutamine family amino acid metabolic process [inference]

arginine metabolic process [inference]

arginine biosynthetic process [inference]

arginine biosynthetic process via ornithine

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process [inference]

arginine biosynthetic process via ornithine

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process [inference]

arginine biosynthetic process via ornithine

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process [inference]

arginine biosynthetic process via ornithine

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process [inference]

arginine biosynthetic process via ornithine

organic substance metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process [inference]

arginine biosynthetic process via ornithine

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process [inference]

arginine biosynthetic process via ornithine

alpha-amino acid metabolic process [inference]

ornithine metabolic process [inference]

arginine biosynthetic process via ornithine

glutamine family amino acid metabolic process [inference]

arginine metabolic process [inference]

arginine biosynthetic process [inference]

arginine biosynthetic process via ornithine

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process [inference]

arginine biosynthetic process via ornithine

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process [inference]

arginine biosynthetic process via ornithine

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process [inference]

arginine biosynthetic process via ornithine

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process [inference]

arginine biosynthetic process via ornithine

alpha-amino acid metabolic process [inference]

ornithine metabolic process [inference]

arginine biosynthetic process via ornithine

glutamine family amino acid metabolic process [inference]

arginine metabolic process [inference]

arginine biosynthetic process [inference]

arginine biosynthetic process via ornithine

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process [inference]

arginine biosynthetic process via ornithine

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process [inference]

arginine biosynthetic process via ornithine

organonitrogen compound biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process [inference]

arginine biosynthetic process via ornithine

organic substance biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process [inference]

arginine biosynthetic process via ornithine

organonitrogen compound biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process [inference]

arginine biosynthetic process via ornithine

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process [inference]

arginine biosynthetic process via ornithine

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process [inference]

arginine biosynthetic process via ornithine

alpha-amino acid metabolic process [inference]

ornithine metabolic process [inference]

arginine biosynthetic process via ornithine

glutamine family amino acid metabolic process [inference]

arginine metabolic process [inference]

arginine biosynthetic process [inference]

arginine biosynthetic process via ornithine

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process [inference]

arginine biosynthetic process via ornithine

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process [inference]

arginine biosynthetic process via ornithine

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process [inference]

arginine biosynthetic process via ornithine

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

glutamine family amino acid biosynthetic process [inference]

arginine biosynthetic process [inference]

arginine biosynthetic process via ornithine

Displaying **all 5** entries
GO Term	Evidence Code	PMID
cytosol	HDA	28887381
chloroplast	ISM
chloroplast	IDA	16377628
chloroplast	HDA	18431481
chloroplast thylakoid	HDA	20061580

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

plastid [inference]

chloroplast

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

thylakoid [inference]

plastid thylakoid [inference]

chloroplast thylakoid

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

plastid [inference]

chloroplast

intracellular non-membrane-bounded organelle [inference]

thylakoid [inference]

plastid thylakoid [inference]

chloroplast thylakoid

Displaying **all 3** entries
GO Term	Evidence Code	PMID
acetylglutamate kinase activity	IDA	16377628
protein binding	IPI	16377628 17913711 19631611 20018655
arginine binding	IDA	17913711

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

acetylglutamate kinase activity

phosphotransferase activity, carboxyl group as acceptor [inference]

acetylglutamate kinase activity

binding [inference]

protein binding

small molecule binding [inference]

organic acid binding [inference]

carboxylic acid binding [inference]

amino acid binding [inference]

arginine binding

ion binding [inference]

anion binding [inference]

carboxylic acid binding [inference]

amino acid binding [inference]

arginine binding

cation binding [inference]

arginine binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

N-acetyl-gamma-glutamyl-phosphate reductase

Functional Category

E: Amino acid transport and metabolism
J: Translation, ribosomal structure and biogenesis
K: Transcription

Displaying entries **1 - 10** of 16 in total

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Gene Ontology
ATP binding
N-acetyl-gamma-glutamyl-phosphate reductase activity
NADP+ binding
acetyl-CoA
acetylglutamate kinase activity
alpha-amino acid metabolic process
amino acid biosynthetic process
arginine biosynthetic process
catalytic activity
glutamate metabolic process

Displaying **all 9** entries
InterPro
Acetylglutamate kinase family
Acetylglutamate kinase-like superfamily
Aspartate/glutamate/uridylate kinase
N-Acetyl-L-glutamate kinase, fungal-type
N-acetyl-gamma-glutamyl-phosphate reductase, active site
N-acetyl-gamma-glutamyl-phosphate reductase, type 1
NAD(P)-binding domain superfamily
Semialdehyde dehydrogenase, NAD-binding
Vertebrate-like NAGS Gcn5-related N-acetyltransferase (GNAT) domain

KEGG BRITE Database

Orthology

K00930

Name

acetylglutamate kinase [EC:2.7.2.8]

References

2851495

Rhea

ATP + N-acetyl-L-glutamate

ADP + N-acetyl-L-glutamyl 5-phosphate

Enzyme

2.7.2.8

PMID

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Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025