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H2B clustered histone 8

Summary

Gene Symbol

H2BC8

Organism

Homo sapiens (human)

External Links

NCBI Gene

8339

PubChem

8339

Alliance of Genome Resources

HGNC:4746

Annotation

Keyword

3D-structure
ADP-ribosylation
Acetylation
Antibiotic
Direct protein sequencing
Glycoprotein
Hydroxylation
Isopeptide bond
Methylation
Nucleosome core
Nucleus
Phosphoprotein
Reference proteome
Ubl conjugation

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P62807	Histone H2B.1 A Histone H2B.a Histone H2B.g Histone H2B.h Histone H2B.k Histone H2B.l
B2R4S9

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
innate immune response in mucosa	IDA	12860195
nucleosome assembly	NAS	422550 9119399
antibacterial humoral response	IDA	12860195
defense response to Gram-positive bacterium	IDA	12860195
antimicrobial humoral immune response mediated by antimicrobial peptide	IDA	12860195

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

organ or tissue specific immune response [inference]

mucosal immune response [inference]

innate immune response in mucosa

humoral immune response [inference]

antimicrobial humoral response [inference]

innate immune response [inference]

innate immune response in mucosa

cellular process [inference]

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein-DNA complex assembly [inference]

nucleosome assembly

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein-DNA complex assembly [inference]

nucleosome assembly

protein-DNA complex organization [inference]

chromatin organization [inference]

chromatin remodeling [inference]

nucleosome organization [inference]

nucleosome assembly

protein-DNA complex assembly [inference]

nucleosome assembly

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

defense response to other organism [inference]

antimicrobial humoral response [inference]

defense response to bacterium [inference]

innate immune response [inference]

innate immune response in mucosa

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

antimicrobial humoral response [inference]

defense response to bacterium [inference]

innate immune response [inference]

innate immune response in mucosa

immune response [inference]

organ or tissue specific immune response [inference]

mucosal immune response [inference]

innate immune response in mucosa

humoral immune response [inference]

antimicrobial humoral response [inference]

innate immune response [inference]

innate immune response in mucosa

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

defense response to other organism [inference]

antimicrobial humoral response [inference]

defense response to bacterium [inference]

innate immune response [inference]

innate immune response in mucosa

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

defense response to other organism [inference]

antimicrobial humoral response [inference]

defense response to bacterium [inference]

innate immune response [inference]

innate immune response in mucosa

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
nucleosome	NAS	422550 9119399
extracellular space	IDA	12860195
nucleus	HDA	21630459
nucleoplasm	TAS
nucleoplasm	IDA

GO Hierarchy

cellular component

protein-containing complex [inference]

protein-DNA complex [inference]

nucleosome

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle [inference]

nucleus

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying **all 5** entries
GO Term	Evidence Code	PMID
DNA binding	NAS	422550 9119399
protein binding	IPI	25416956 27462807 32296183 35390161
structural constituent of chromatin	IEA
identical protein binding	IPI	25954010
protein heterodimerization activity	IEA

GO Hierarchy

molecular function

structural molecule activity [inference]

structural constituent of chromatin

binding [inference]

protein binding

identical protein binding

protein dimerization activity [inference]

protein heterodimerization activity

organic cyclic compound binding [inference]

nucleic acid binding [inference]

DNA binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Histone H2B

Functional Category

J: Translation, ribosomal structure and biogenesis

Displaying **all 6** entries
Gene Ontology
antimicrobial humoral immune response mediated by antimicrobial peptide
defense response to Gram-positive bacterium
innate immune response in mucosa
nucleosome assembly
protein heterodimerization activity
structural constituent of chromatin