GlyCosmos Portal

Submissions

Disease resistance protein (TIR-NBS-LRR class) family

Summary

Gene Symbol

LAZ5

Organism

Arabidopsis thaliana (thale cress)

External Links

NCBI Gene: 834517
PubChem: 834517

Annotation

Keyword

ATP-binding
Hydrolase
Leucine-rich repeat
NAD
Plant defense
Proteomics identification
Reference proteome
Repeat

Proteins

Displaying **all 3** entries
UniProt	Protein Name
O48573	Protein LAZARUS 5 Protein TOLERANCE TO TOBACCO RINGSPOT VIRUS 1
A0A178ULB4
A0A1P8BES3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
defense response	IEA
signal transduction	IEA
response to virus	IMP	8870272
plant-type hypersensitive response	IMP	20949080 8870272
defense response to virus	IMP	22057987

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

innate immune response [inference]

plant-type hypersensitive response

cellular process [inference]

signal transduction

cell death [inference]

programmed cell death [inference]

programmed cell death induced by symbiont [inference]

plant-type hypersensitive response

cellular response to stimulus [inference]

cellular response to stress [inference]

plant-type hypersensitive response

biological process involved in interspecies interaction between organisms [inference]

biological process involved in symbiotic interaction [inference]

biological process involved in interaction with symbiont [inference]

programmed cell death induced by symbiont [inference]

plant-type hypersensitive response

response to other organism [inference]

response to virus

defense response to virus

defense response to other organism [inference]

programmed cell death induced by symbiont [inference]

plant-type hypersensitive response

innate immune response [inference]

plant-type hypersensitive response

defense response to symbiont [inference]

defense response to virus

response to stimulus [inference]

response to stress [inference]

defense response

defense response to other organism [inference]

programmed cell death induced by symbiont [inference]

plant-type hypersensitive response

innate immune response [inference]

plant-type hypersensitive response

defense response to symbiont [inference]

defense response to virus

cellular response to stress [inference]

plant-type hypersensitive response

immune response [inference]

innate immune response [inference]

plant-type hypersensitive response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to virus

defense response to virus

defense response to other organism [inference]

programmed cell death induced by symbiont [inference]

plant-type hypersensitive response

innate immune response [inference]

plant-type hypersensitive response

defense response to symbiont [inference]

defense response to virus

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to virus

defense response to virus

defense response to other organism [inference]

programmed cell death induced by symbiont [inference]

plant-type hypersensitive response

innate immune response [inference]

plant-type hypersensitive response

defense response to symbiont [inference]

defense response to virus

cellular response to stimulus [inference]

cellular response to stress [inference]

plant-type hypersensitive response

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction

Displaying 1 entry
GO Term	Evidence Code	PMID
cytoplasm	ISM

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

Displaying **all 4** entries
GO Term	Evidence Code	PMID
NAD+ nucleosidase activity
ATP binding
ADP binding	IEA
NAD+ nucleotidase, cyclic ADP-ribose generating	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing N-glycosyl compounds [inference]

NAD+ nucleosidase activity

NAD+ nucleotidase, cyclic ADP-ribose generating

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

ADP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

disease resistance protein LAZ5

Functional Category

K: Transcription
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
ADP binding

Displaying **all 9** entries
InterPro
Apoptotic protease-activating factors, helical domain
C-JID domain
Disease resistance protein, plants
Leucine-rich repeat 3
Leucine-rich repeat domain superfamily
NB-ARC
P-loop containing nucleoside triphosphate hydrolase
Toll/interleukin-1 receptor homology (TIR) domain superfamily
Toll/interleukin-1 receptor homology (TIR) domain