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MIRAGE

NUF2 component of NDC80 kinetochore complex

Summary

Gene Symbol

NUF2

Organism

Homo sapiens (human)

External Links

NCBI Gene

83540

PubChem

83540

Alliance of Genome Resources

HGNC:14621

JoGo

NUF2

TogoVar

NUF2

Gene Ontology (GO)

Displaying entries **6 - 8** of 8 in total

« First

‹ Prev

1

2
GO Term	Evidence Code	PMID
cell division	IEA
attachment of mitotic spindle microtubules to kinetochore	IBA
kinetochore organization	IBA

GO Hierarchy

biological process

cellular process [inference]

microtubule-based process [inference]

microtubule cytoskeleton organization [inference]

spindle organization [inference]

mitotic spindle organization

microtubule cytoskeleton organization involved in mitosis [inference]

mitotic spindle organization

signal transduction [inference]

intracellular signal transduction [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

spindle checkpoint signaling [inference]

spindle assembly checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

cell cycle process [inference]

spindle organization [inference]

mitotic spindle organization

chromosome segregation

nuclear chromosome segregation [inference]

meiotic chromosome segregation

attachment of spindle microtubules to kinetochore

attachment of mitotic spindle microtubules to kinetochore

meiotic cell cycle process [inference]

meiotic chromosome segregation

mitotic cell cycle process [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

attachment of mitotic spindle microtubules to kinetochore

microtubule cytoskeleton organization involved in mitosis [inference]

mitotic spindle organization

cell division

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

microtubule cytoskeleton organization [inference]

spindle organization [inference]

mitotic spindle organization

microtubule cytoskeleton organization involved in mitosis [inference]

mitotic spindle organization

chromosome organization [inference]

kinetochore organization

reproductive process [inference]

meiotic cell cycle process [inference]

meiotic chromosome segregation

biological regulation [inference]

regulation of biological process [inference]

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of chromosome segregation [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of chromosome separation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

spindle checkpoint signaling [inference]

spindle assembly checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of metaphase/anaphase transition of cell cycle [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of mitotic cell cycle [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of nuclear division [inference]

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of chromosome organization [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

regulation of cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

spindle checkpoint signaling [inference]

spindle assembly checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of cellular process [inference]

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of chromosome segregation [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of chromosome separation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

spindle checkpoint signaling [inference]

spindle assembly checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of metaphase/anaphase transition of cell cycle [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of mitotic cell cycle [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of nuclear division [inference]

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of chromosome organization [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

negative regulation of organelle organization [inference]

negative regulation of nuclear division [inference]

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of chromosome organization [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

regulation of chromosome organization [inference]

regulation of sister chromatid segregation [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

regulation of metaphase/anaphase transition of cell cycle [inference]

regulation of mitotic metaphase/anaphase transition [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of metaphase/anaphase transition of cell cycle [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of chromosome organization [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

regulation of nuclear division [inference]

regulation of mitotic nuclear division [inference]

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of nuclear division [inference]

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of nuclear division [inference]

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of chromosome organization [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

regulation of cell cycle [inference]

regulation of mitotic cell cycle [inference]

regulation of mitotic nuclear division [inference]

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of mitotic cell cycle [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

regulation of mitotic cell cycle phase transition [inference]

regulation of mitotic metaphase/anaphase transition [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

regulation of cell cycle process [inference]

regulation of mitotic nuclear division [inference]

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of cell cycle process [inference]

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of chromosome segregation [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of chromosome separation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

spindle checkpoint signaling [inference]

spindle assembly checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of metaphase/anaphase transition of cell cycle [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

regulation of chromosome segregation [inference]

regulation of sister chromatid segregation [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

regulation of metaphase/anaphase transition of cell cycle [inference]

regulation of mitotic metaphase/anaphase transition [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of metaphase/anaphase transition of cell cycle [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of chromosome segregation [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of chromosome separation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

regulation of chromosome separation [inference]

regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of chromosome separation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

regulation of cell cycle phase transition [inference]

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

spindle checkpoint signaling [inference]

spindle assembly checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of metaphase/anaphase transition of cell cycle [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

regulation of mitotic cell cycle phase transition [inference]

regulation of mitotic metaphase/anaphase transition [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

regulation of metaphase/anaphase transition of cell cycle [inference]

regulation of mitotic metaphase/anaphase transition [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of metaphase/anaphase transition of cell cycle [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of chromosome segregation [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of chromosome separation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

spindle checkpoint signaling [inference]

spindle assembly checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of metaphase/anaphase transition of cell cycle [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of mitotic cell cycle [inference]

mitotic cell cycle checkpoint signaling [inference]

mitotic spindle checkpoint signaling [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition [inference]

mitotic spindle assembly checkpoint signaling

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
kinetochore	NAS	23418356
kinetochore	IDA	15961401
outer kinetochore	IDA	24530301
nucleoplasm	IDA
cytosol	TAS

GO Hierarchy

cellular component

protein-containing complex [inference]

cellular anatomical entity [inference]

organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

kinetochore

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

kinetochore

supramolecular complex [inference]

kinetochore

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein binding	IPI	14699129 15961401 17043677 17129783 17535814 20360068 22581055 24981860 25416956 26068854 26496610 31413325 33961781 35271311
microtubule binding	IMP	18455984
protein-containing complex binding	IBA

GO Hierarchy

molecular function

binding [inference]

protein binding

cytoskeletal protein binding [inference]

tubulin binding [inference]

microtubule binding

protein-containing complex binding

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0080909	castration-resistant prostate carcinoma	Alliance of Genome Resources
DOID:1793	pancreatic cancer	Alliance of Genome Resources

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Last updated: April 6, 2026