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MIRAGE

N-acetylated alpha-linked acidic dipeptidase-like 1

Summary

Gene Symbol

Naaladl1

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

83568

PubChem

83568

Alliance of Genome Resources

RGD:620987

Annotation

Keyword

Aminopeptidase
Calcium
Cell membrane
Direct protein sequencing
Disulfide bond
Glycoprotein
Metal-binding
Metalloprotease
Reference proteome
Signal-anchor
Transmembrane helix
Zinc

Proteins

Displaying **all 2** entries
UniProt	Protein Name
O54697	100 kDa ileum brush border membrane protein Ileal dipeptidylpeptidase N-acetylated-alpha-linked acidic dipeptidase-like protein
A6HZE0

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
proteolysis	IEA
peptide catabolic process	ISS
peptide catabolic process	ISO
peptide catabolic process	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

amide metabolic process [inference]

peptide metabolic process [inference]

peptide catabolic process

organonitrogen compound metabolic process [inference]

peptide metabolic process [inference]

peptide catabolic process

protein metabolic process [inference]

proteolysis

organonitrogen compound catabolic process [inference]

peptide catabolic process

catabolic process [inference]

cellular catabolic process [inference]

peptide catabolic process

organic substance catabolic process [inference]

organonitrogen compound catabolic process [inference]

peptide catabolic process

cellular metabolic process [inference]

cellular catabolic process [inference]

peptide catabolic process

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis

organonitrogen compound metabolic process [inference]

peptide metabolic process [inference]

peptide catabolic process

protein metabolic process [inference]

proteolysis

organonitrogen compound catabolic process [inference]

peptide catabolic process

organic substance catabolic process [inference]

organonitrogen compound catabolic process [inference]

peptide catabolic process

cellular process [inference]

cellular metabolic process [inference]

cellular catabolic process [inference]

peptide catabolic process

Displaying **all 3** entries
GO Term	Evidence Code	PMID
plasma membrane	IEA
membrane	IDA	9388249
apical plasma membrane	IDA	9388249

GO Hierarchy

cellular component

cellular anatomical entity [inference]

plasma membrane

plasma membrane region [inference]

apical plasma membrane

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	PMID
aminopeptidase activity	ISS
aminopeptidase activity	ISO
aminopeptidase activity	IEA
carboxypeptidase activity	IBA
calcium ion binding	ISS

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

metallopeptidase activity

exopeptidase activity [inference]

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

metallopeptidase activity

exopeptidase activity [inference]

binding [inference]

protein binding [inference]

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

transition metal ion binding [inference]

zinc ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

N-acetylated-alpha-linked acidic dipeptidase

Functional Category

E: Amino acid transport and metabolism
M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones

Displaying 1 entry
Gene Ontology
carboxypeptidase activity

Displaying **all 6** entries
InterPro
PA domain superfamily
PA domain
Peptidase M28
Transferrin receptor protein 1/Glutamate carboxypeptidase 2-like
Transferrin receptor-like, dimerisation domain superfamily
Transferrin receptor-like, dimerisation domain

Ortholog

Displaying entries **1 - 10** of 80 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Saccharomyces cerevisiae S288C	2346	SGD:S000003887
Saccharomyces cerevisiae S288C	7036	SGD:S000005782
Saccharomyces cerevisiae S288C	7037	SGD:S000005782
Saccharomyces cerevisiae S288C	10003	SGD:S000003887
Homo sapiens	10004	Xenbase:XB-GENE-5831737	HUMAN07019
Saccharomyces cerevisiae S288C	22042	SGD:S000005782
Saccharomyces cerevisiae S288C	50765	SGD:S000005782
Saccharomyces cerevisiae S288C	53320	SGD:S000003887
Saccharomyces cerevisiae S288C	64678	SGD:S000005782
Saccharomyces cerevisiae S288C	72560	SGD:S000006097

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.4.0

Last updated: December 8, 2025