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gamma-aminobutyric acid type B receptor subunit 2

Summary

Gene Symbol

Gabbr2

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

83633

PubChem

83633

Alliance of Genome Resources

RGD:619864

Annotation

Keyword

Cell membrane
Cell projection
Coiled coil
Disulfide bond
G-protein coupled receptor
Glycoprotein
Phosphoprotein
Postsynaptic cell membrane
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
O88871	G-protein coupled receptor 51

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
gamma-aminobutyric acid signaling pathway	IDA	11389174 15147298
gamma-aminobutyric acid signaling pathway	IBA
gamma-aminobutyric acid signaling pathway	IEA
synaptic transmission, GABAergic	NAS	15147298
neuron-glial cell signaling	IGI	10196584

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

gamma-aminobutyric acid signaling pathway

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission [inference]

synaptic transmission, GABAergic

neuron-glial cell signaling

signal transduction [inference]

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway

biological regulation [inference]

regulation of biological process [inference]

signaling [inference]

cell-cell signaling [inference]

gamma-aminobutyric acid signaling pathway

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission [inference]

synaptic transmission, GABAergic

neuron-glial cell signaling

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway

Displaying entries **11 - 15** of 20 in total

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GO Term	Evidence Code	PMID
presynaptic membrane	IDA	14657159
neuron projection	ISO
neuron projection	IEA
perikaryon	IEA
postsynaptic membrane	IDA	14657159

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex [inference]

plasma membrane signaling receptor complex [inference]

G protein-coupled receptor complex [inference]

G protein-coupled receptor dimeric complex [inference]

GABA receptor complex

G protein-coupled GABA receptor complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

plasma membrane signaling receptor complex [inference]

G protein-coupled receptor complex [inference]

G protein-coupled receptor dimeric complex [inference]

cellular anatomical entity [inference]

cytoplasm

membrane [inference]

plasma membrane

plasma membrane region [inference]

synaptic membrane [inference]

cell junction [inference]

synapse [inference]

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection

dendrite

perikaryon

Displaying entries **6 - 7** of 7 in total

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GO Term	Evidence Code	PMID
protein heterodimerization activity	ISO
protein heterodimerization activity	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding

protein dimerization activity [inference]

protein heterodimerization activity

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity [inference]

G protein-coupled GABA receptor activity

GABA receptor activity [inference]

G protein-coupled GABA receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

receptor

Functional Category

E: Amino acid transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
G protein-coupled GABA receptor activity
gamma-aminobutyric acid signaling pathway

Displaying **all 4** entries
InterPro
GPCR family 3, C-terminal
GPCR family 3, GABA-B receptor
Periplasmic binding protein-like I
Receptor, ligand binding region

Ortholog

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	9568	Xenbase:XB-GENE-5815161	HUMAN97783
Xenopus tropicalis	83633	Xenbase:XB-GENE-5815161
Xenopus tropicalis	191240	Xenbase:XB-GENE-5815161
Mus musculus	242425	Xenbase:XB-GENE-5815161	MOUSE43037
Pan troglodytes	464609		PANTR44439
Canis lupus familiaris	481627		CANLF02353
Danio rerio	560267		DANRE15107
Macaca mulatta	718019		MACMU12109
Equus caballus	100063963		HORSE24175
Taeniopygia guttata	100222507		TAEGU17033