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gamma-aminobutyric acid type B receptor subunit 2

Summary

Gene Symbol

Gabbr2

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

83633

PubChem

83633

Alliance of Genome Resources

RGD:619864

Annotation

Keyword

Cell membrane
Cell projection
Coiled coil
Disulfide bond
G-protein coupled receptor
Glycoprotein
Phosphoprotein
Postsynaptic cell membrane
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
O88871	G-protein coupled receptor 51

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
G protein-coupled receptor signaling pathway	IEA
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	ISO
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	IDA	15147298
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	IEA
gamma-aminobutyric acid signaling pathway	ISO

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

gamma-aminobutyric acid signaling pathway

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission [inference]

synaptic transmission, GABAergic

neuron-glial cell signaling

signal transduction [inference]

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway

biological regulation [inference]

regulation of biological process [inference]

signaling [inference]

cell-cell signaling [inference]

gamma-aminobutyric acid signaling pathway

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission [inference]

synaptic transmission, GABAergic

neuron-glial cell signaling

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway

Displaying entries **1 - 5** of 20 in total

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GO Term	Evidence Code	PMID
cytoplasm	ISO
cytoplasm	IEA
plasma membrane	ISS
plasma membrane	ISO
plasma membrane	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex [inference]

plasma membrane signaling receptor complex [inference]

G protein-coupled receptor complex [inference]

G protein-coupled receptor dimeric complex [inference]

GABA receptor complex

G protein-coupled GABA receptor complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

plasma membrane signaling receptor complex [inference]

G protein-coupled receptor complex [inference]

G protein-coupled receptor dimeric complex [inference]

cellular anatomical entity [inference]

cytoplasm

membrane [inference]

plasma membrane

plasma membrane region [inference]

synaptic membrane [inference]

cell junction [inference]

synapse [inference]

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection

dendrite

perikaryon

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GO Term	Evidence Code	PMID
G protein-coupled GABA receptor activity	ISO
G protein-coupled GABA receptor activity	IDA	11389174
G protein-coupled GABA receptor activity	IBA
G protein-coupled GABA receptor activity	IEA
protein binding	IPI	19590495 20627102 21063387 21552208

GO Hierarchy

molecular function

binding [inference]

protein binding

protein dimerization activity [inference]

protein heterodimerization activity

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity [inference]

G protein-coupled GABA receptor activity

GABA receptor activity [inference]

G protein-coupled GABA receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

gamma-aminobutyric acid type B receptor subunit 2

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
G protein-coupled GABA receptor activity
gamma-aminobutyric acid signaling pathway

Displaying **all 7** entries
InterPro
GPCR family 3, C-terminal
GPCR family 3, GABA-B receptor
GPCR family 3, gamma-aminobutyric acid receptor, type B2
GPCR, family 3, conserved site
Gamma-aminobutyric acid type B receptor subunit 2, coiled-coil domain
Periplasmic binding protein-like I
Receptor, ligand binding region

Ortholog

Displaying entries **21 - 30** of 55 in total

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Species	Gene ID	Orthologous MAtrix
Mustela putorius furo	101690704	MUSPF15526
Ictidomys tridecemlineatus	101962580	ICTTR00656
Chinchilla lanigera	102017341	CHILA06669
Capra hircus	102186689	CAPHI29186
Astyanax mexicanus	103026663	ASTMX12258
Callorhinchus milii	103186359	CALMI34453
Chlorocebus sabaeus	103219146	CHLSB03194
Nannospalax galili	103748349	NANGA25891
Rhinopithecus roxellana	104657770	RHIRO15788
Macaca nemestrina	105477203	MACNE18047