GlyCosmos Portal

Submissions

endonuclease III 2

Summary

Gene Symbol

NTH2

Organism

Arabidopsis thaliana (thale cress)

External Links

NCBI Gene: 837100
PubChem: 837100

Annotation

Keyword

4Fe-4S
Alternative splicing
Chloroplast
DNA repair
Glycosidase
Lyase
Reference proteome
Transit peptide

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A178W393	Bifunctional DNA N-glycosylase/DNA-(apurinic or apyrimidinic site) lyase
B9DFZ0	Bifunctional DNA N-glycosylase/DNA-(apurinic or apyrimidinic site) lyase 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
base-excision repair	IDA	19372224
base-excision repair, AP site formation

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

base-excision repair

base-excision repair, AP site formation

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

base-excision repair

base-excision repair, AP site formation

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

base-excision repair

base-excision repair, AP site formation

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

base-excision repair

base-excision repair, AP site formation

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

base-excision repair

base-excision repair, AP site formation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

base-excision repair

base-excision repair, AP site formation

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

base-excision repair

base-excision repair, AP site formation

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

base-excision repair

base-excision repair, AP site formation

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

base-excision repair

base-excision repair, AP site formation

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

base-excision repair

base-excision repair, AP site formation

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair [inference]

base-excision repair

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair [inference]

base-excision repair

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair [inference]

base-excision repair

Displaying **all 3** entries
GO Term	Evidence Code	PMID
nucleus	ISM
mitochondrion	ISM
chloroplast nucleoid	IDA	19372224

GO Hierarchy

cellular component

cellular anatomical entity [inference]

nucleoid [inference]

plastid nucleoid [inference]

chloroplast nucleoid

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

plastid nucleoid [inference]

chloroplast nucleoid

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

plastid nucleoid [inference]

chloroplast nucleoid

Displaying entries **1 - 5** of 7 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity
DNA binding
DNA-(apurinic or apyrimidinic site) endonuclease activity	IDA	19372224
DNA N-glycosylase activity	IDA	19372224
metal ion binding

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing N-glycosyl compounds [inference]

DNA N-glycosylase activity

oxidized base lesion DNA N-glycosylase activity [inference]

oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity

lyase activity [inference]

carbon-oxygen lyase activity [inference]

class I DNA-(apurinic or apyrimidinic site) endonuclease activity

catalytic activity, acting on a nucleic acid [inference]

catalytic activity, acting on DNA [inference]

DNA-(apurinic or apyrimidinic site) endonuclease activity

class I DNA-(apurinic or apyrimidinic site) endonuclease activity

DNA N-glycosylase activity

oxidized base lesion DNA N-glycosylase activity [inference]

oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

metal cluster binding [inference]

iron-sulfur cluster binding [inference]

4 iron, 4 sulfur cluster binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

DNA binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

endonuclease

Functional Category

K: Transcription
L: Replication, recombination and repair
T: Signal transduction mechanisms

Displaying **all 9** entries
Gene Ontology
4 iron, 4 sulfur cluster binding
DNA repair
DNA-(apurinic or apyrimidinic site) endonuclease activity
base-excision repair, AP site formation
base-excision repair
catalytic activity
hydrolase activity, acting on glycosyl bonds
hydrolase activity
lyase activity

Displaying **all 6** entries
InterPro
DNA glycosylase
Endonuclease III-like protein 1
Endonuclease III-like, conserved site-2
Helix-hairpin-helix motif
Helix-hairpin-helix, base-excision DNA repair, C-terminal
HhH-GPD domain