phospholipase A2 group VI
| UniProt | Protein Name |
|---|---|
| O60733 |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| chemotaxis | ||
| antibacterial humoral response | ||
| phosphatidylcholine catabolic process | ||
| positive regulation of insulin secretion involved in cellular response to glucose stimulus | ||
| cardiolipin acyl-chain remodeling |
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular space | ||
| mitochondrion | ||
| mitochondrion | ||
| cytosol | ||
| plasma membrane |
| GO Term | Evidence Code | PMID |
|---|---|---|
| 1-alkyl-2-acetylglycerophosphocholine esterase activity | ||
| lysophospholipase activity | ||
| phospholipase A2 activity | ||
| protein binding | ||
| calmodulin binding |
| Gene Ontology |
|---|
| calcium-independent phospholipase A2 activity |
| cardiolipin acyl-chain remodeling |
| hydrolase activity |
| lipid metabolic process |
| positive regulation of ceramide biosynthetic process |
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060900 | Parkinson's disease 14 | |
| DOID:0090056 | dystonia 12 | |
| DOID:0110735 | neurodegeneration with brain iron accumulation 2a | |
| DOID:0110736 | neurodegeneration with brain iron accumulation 2b | |
| DOID:14330 | Parkinson's disease | |
| DOID:2367 | neuroaxonal dystrophy |
| HPO ID | HPO Term |
|---|---|
| HP:0000007 | Autosomal recessive inheritance |
| HP:0000017 | Nocturia |
| HP:0000338 | Hypomimic face |
| HP:0000347 | Micrognathia |
| HP:0000365 | Hearing impairment |
| HP:0000486 | Strabismus |
| HP:0000511 | Vertical supranuclear gaze palsy |
| HP:0000571 | Hypometric saccades |
| HP:0000572 | Visual loss |
| HP:0000605 | Supranuclear gaze palsy |
| Disease ID | Disease Name |
|---|---|
| OMIM:610217 |
|
| ORPHA:35069 |
|
| ORPHA:199351 |
|
| OMIM:256600 |
|
| OMIM:612953 |
|
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 8398 | Xenbase:XB-GENE-920447 | ||
| 53357 | Xenbase:XB-GENE-920447 | MOUSE16942 | |
| 360426 | RATNO38024 | ||
| 406370 | DANRE23128 | ||
| 470208 | PANTR26555 | ||
| 481256 | CANLF01620 | ||
| 535381 | BOVIN30650 | ||
| 100016178 | MONDO00647 | ||
| 100090638 | ORNAN06146 | ||
| 100222459 | TAEGU09100 |
GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.
Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
This work is licensed under Creative Commons Attribution 4.0 International
GlyCosmos Portal v4.3.0
Last updated: August 4, 2025