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MIRAGE
caspase 7

Summary
Gene Symbol
  • CASP7
Organism
Homo sapiens (human)
NCBI Gene
840
PubChem
840
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • Acetylation
  • Allosteric enzyme
  • Alternative splicing
  • Apoptosis
  • Cytoplasm
  • Nucleus
  • Phosphoprotein
  • Proteomics identification
  • RNA-binding
  • Reference proteome
  • Secreted
  • Thiol protease
  • Zymogen
Proteins
Displaying all 3 entries
UniProt Protein Name
B4DWA2
P55210
  • Apoptotic protease Mch-3
  • CMH-1
  • ICE-like apoptotic protease 3
A0A0A0MRL7
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entries 1 - 5 of 19 in total
GO Term Evidence Code PMID
proteolysis
apoptotic process
apoptotic process
heart development
response to UV
GO Hierarchy
Displaying entry 11 - 11 of 11 in total
GO Term Evidence Code PMID
cysteine-type endopeptidase activity involved in execution phase of apoptosis
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
Caspase
Functional Category
  • E: Amino acid transport and metabolism
  • O: Posttranslational modification, protein turnover, chaperones
  • T: Signal transduction mechanisms
Displaying all 4 entries
Gene Ontology
cysteine-type endopeptidase activity
hydrolase activity
positive regulation of neuron apoptotic process
proteolysis
Displaying all 7 entries
InterPro
Caspase-like domain superfamily
Peptidase C14, caspase domain
Peptidase C14, caspase non-catalytic subunit p10
Peptidase C14, p20 domain
Peptidase C14A, caspase catalytic domain
Peptidase family C14A, His active site
Peptidase family C14A, cysteine active site
Disease
Disease Ontology
Displaying all 4 entries
DO ID Disease Name Source
DOID:10652 Alzheimer's disease
DOID:1612 breast cancer
DOID:219 colon cancer
DOID:3908 lung non-small cell carcinoma
Ortholog
Displaying entries 41 - 50 of 77 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
103657312 URSMA04189
103813818 SERCA07478
104662231 RHIRO23212
105291475 PTEVA09671
105466939 MACNE27490
105530140 MANLE04096
105577913 CERAT13213
105875340 MICMU15942
105986773 DIPOR07444
106578356 SALSA60956
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025