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synapse defective Rho GTPase homolog 2

Summary

Gene Symbol

SYDE2

Organism

Homo sapiens (human)

External Links

NCBI Gene

84144

PubChem

84144

Alliance of Genome Resources

HGNC:25841

Annotation

Keyword

Alternative splicing
GTPase activation
Phosphoprotein
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
Q5VT97	Synapse defective protein 1 homolog 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
signal transduction	IEA
cell migration	IDA	27917469
cell migration	IBA
regulation of Ras protein signal transduction	IBA
regulation of small GTPase mediated signal transduction	TAS

GO Hierarchy

biological process

cellular process [inference]

signal transduction

cell motility [inference]

cell migration

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction

regulation of Ras protein signal transduction

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction

regulation of Ras protein signal transduction

regulation of cellular process [inference]

signal transduction

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction

regulation of Ras protein signal transduction

regulation of molecular function [inference]

positive regulation of molecular function [inference]

positive regulation of catalytic activity [inference]

positive regulation of hydrolase activity [inference]

positive regulation of GTPase activity [inference]

activation of GTPase activity

regulation of catalytic activity [inference]

positive regulation of catalytic activity [inference]

positive regulation of hydrolase activity [inference]

positive regulation of GTPase activity [inference]

activation of GTPase activity

regulation of hydrolase activity [inference]

regulation of GTPase activity [inference]

positive regulation of GTPase activity [inference]

activation of GTPase activity

positive regulation of hydrolase activity [inference]

positive regulation of GTPase activity [inference]

activation of GTPase activity

Displaying **all 2** entries
GO Term	Evidence Code	PMID
cytosol	TAS
synaptic membrane	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

membrane [inference]

plasma membrane region [inference]

synaptic membrane

Displaying **all 3** entries
GO Term	Evidence Code	PMID
GTPase activator activity	ISS
GTPase activator activity	TAS
GTPase activator activity	IBA

GO Hierarchy

molecular function

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme activator activity [inference]

GTPase activator activity

nucleoside-triphosphatase regulator activity [inference]

GTPase regulator activity [inference]

GTPase activator activity

molecular function activator activity [inference]

enzyme activator activity [inference]

GTPase activator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

rho GTPase-activating protein

Functional Category

C: Energy production and conversion
E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 2** entries
Gene Ontology
cell migration
regulation of Ras protein signal transduction

Displaying **all 4** entries
InterPro
C2 domain superfamily
C2 domain
Rho GTPase activation protein
Rho GTPase-activating protein domain

Ortholog

Displaying entries **11 - 20** of 39 in total

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Species	Gene ID	Orthologous MAtrix
Loxodonta africana	100666458	LOXAF13444
Otolemur garnettii	100955297	OTOGA16760
Pan paniscus	100976608	PANPA01746
Papio anubis	101005307	PAPAN21183
Saimiri boliviensis boliviensis	101039642	SAIBB02636
Felis catus	101092200	FELCA18940
Gorilla gorilla gorilla	101144147	GORGO19210
Mustela putorius furo	101684321	MUSPF13524
Melopsittacus undulatus	101878048	MELUD15319
Capra hircus	102186263	CAPHI22011