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Disease resistance protein (TIR-NBS-LRR class)

Summary

Gene Symbol

WRR4

Organism

Arabidopsis thaliana (thale cress)

External Links

NCBI Gene: 842104
PubChem: 842104

Annotation

Keyword

ATP-binding
Cytoplasm
Hydrolase
Leucine-rich repeat
NAD
Plant defense
Reference proteome
Repeat
Stress response

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9C7X0	Protein ACTIVATED DISEASE RESISTANCE 2 Protein WHITE RUST RESISTANCE 4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
defense response	IEP	31568832
cellular response to UV	IMP	25656510
defense response to oomycetes	IMP	20447277 34181787
signal transduction	IEA
defense response to fungus	IMP	18624640

GO Hierarchy

biological process

cellular process [inference]

signal transduction

cellular response to stimulus [inference]

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to light stimulus [inference]

cellular response to UV

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to oomycetes [inference]

defense response to oomycetes

response to fungus [inference]

defense response to fungus

defense response to other organism [inference]

response to stimulus [inference]

response to stress [inference]

defense response

defense response to other organism [inference]

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to oomycetes [inference]

defense response to oomycetes

response to fungus [inference]

defense response to fungus

defense response to other organism [inference]

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to oomycetes [inference]

defense response to oomycetes

response to fungus [inference]

defense response to fungus

defense response to other organism [inference]

response to abiotic stimulus [inference]

response to radiation [inference]

response to light stimulus [inference]

response to UV [inference]

cellular response to UV

cellular response to light stimulus [inference]

cellular response to UV

cellular response to radiation [inference]

cellular response to light stimulus [inference]

cellular response to UV

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to light stimulus [inference]

cellular response to UV

cellular response to stimulus [inference]

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to light stimulus [inference]

cellular response to UV

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction

Displaying **all 2** entries
GO Term	Evidence Code	PMID
chloroplast	ISM
cytoplasm	IDA	18624640

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

plastid [inference]

chloroplast

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

plastid [inference]

chloroplast

Displaying **all 4** entries
GO Term	Evidence Code	PMID
NAD+ nucleosidase activity
NAD+ nucleotidase, cyclic ADP-ribose generating	IEA
ADP binding	IEA
ATP binding

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing N-glycosyl compounds [inference]

NAD+ nucleosidase activity

NAD+ nucleotidase, cyclic ADP-ribose generating

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

ADP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

Gene Ontology information from NCBI Gene and UniProt.

Rhea

RHEA:16301

H₂O + NAD⁺

H⁺ + nicotinamide + ADP-D-ribose

Enzyme

PMID

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024

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