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dehydroascorbate reductase 2

Summary

Gene Symbol

DHAR2

Organism

Arabidopsis thaliana (thale cress)

External Links

NCBI Gene: 843864
PubChem: 843864

Annotation

Keyword

3D-structure
Cytoplasm
Detoxification
Glutathionylation
Oxidoreductase
Reference proteome
Stress response
Transferase

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9FRL8	Chloride intracellular channel homolog 2 Glutathione-dependent dehydroascorbate reductase 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
acquisition of seed longevity	IGI	32519347
positive regulation of salicylic acid mediated signaling pathway	IGI	28381499
cellular response to hydrogen peroxide	IGI	28381499
L-ascorbic acid metabolic process	IGI	32205453
protein glutathionylation	IDA	12077129

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glutathionylation

catabolic process [inference]

cellular catabolic process [inference]

hydrogen peroxide catabolic process [inference]

ascorbate glutathione cycle

organic substance catabolic process [inference]

hydrogen peroxide catabolic process [inference]

ascorbate glutathione cycle

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

L-ascorbic acid metabolic process

ascorbate glutathione cycle

cellular catabolic process [inference]

hydrogen peroxide catabolic process [inference]

ascorbate glutathione cycle

heterocycle metabolic process [inference]

lactone metabolic process [inference]

L-ascorbic acid metabolic process

ascorbate glutathione cycle

reactive oxygen species metabolic process [inference]

hydrogen peroxide metabolic process [inference]

hydrogen peroxide catabolic process [inference]

ascorbate glutathione cycle

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

L-ascorbic acid metabolic process

ascorbate glutathione cycle

protein metabolic process [inference]

protein modification process [inference]

protein glutathionylation

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

L-ascorbic acid metabolic process

ascorbate glutathione cycle

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

L-ascorbic acid metabolic process

ascorbate glutathione cycle

vitamin metabolic process [inference]

water-soluble vitamin metabolic process [inference]

L-ascorbic acid metabolic process

ascorbate glutathione cycle

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

L-ascorbic acid metabolic process

ascorbate glutathione cycle

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

L-ascorbic acid metabolic process

ascorbate glutathione cycle

glutathione metabolic process [inference]

ascorbate glutathione cycle

hydrogen peroxide metabolic process [inference]

hydrogen peroxide catabolic process [inference]

ascorbate glutathione cycle

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glutathionylation

macromolecule modification [inference]

protein modification process [inference]

protein glutathionylation

organic cyclic compound metabolic process [inference]

lactone metabolic process [inference]

L-ascorbic acid metabolic process

ascorbate glutathione cycle

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glutathionylation

organic substance catabolic process [inference]

hydrogen peroxide catabolic process [inference]

ascorbate glutathione cycle

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

L-ascorbic acid metabolic process

ascorbate glutathione cycle

cellular catabolic process [inference]

hydrogen peroxide catabolic process [inference]

ascorbate glutathione cycle

heterocycle metabolic process [inference]

lactone metabolic process [inference]

L-ascorbic acid metabolic process

ascorbate glutathione cycle

reactive oxygen species metabolic process [inference]

hydrogen peroxide metabolic process [inference]

hydrogen peroxide catabolic process [inference]

ascorbate glutathione cycle

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

cellular response to chemical stimulus [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

cellular response to oxygen-containing compound [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

cellular detoxification [inference]

cellular oxidant detoxification

reproductive process [inference]

acquisition of seed longevity

multicellular organismal process [inference]

acquisition of seed longevity

response to stimulus [inference]

response to stress [inference]

response to oxidative stress [inference]

response to reactive oxygen species [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

response to hydrogen peroxide [inference]

cellular response to hydrogen peroxide

cellular response to oxidative stress [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

cellular response to stress [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

response to chemical [inference]

response to organic substance [inference]

response to hydrogen peroxide [inference]

cellular response to hydrogen peroxide

response to inorganic substance [inference]

response to hydrogen peroxide [inference]

cellular response to hydrogen peroxide

cellular response to chemical stimulus [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

cellular response to oxygen-containing compound [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

response to oxygen-containing compound [inference]

response to reactive oxygen species [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

response to hydrogen peroxide [inference]

cellular response to hydrogen peroxide

cellular response to oxygen-containing compound [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

cellular response to chemical stimulus [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

cellular response to oxygen-containing compound [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of salicylic acid mediated signaling pathway

regulation of salicylic acid mediated signaling pathway [inference]

positive regulation of salicylic acid mediated signaling pathway

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of salicylic acid mediated signaling pathway

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of salicylic acid mediated signaling pathway

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of salicylic acid mediated signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of salicylic acid mediated signaling pathway

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of salicylic acid mediated signaling pathway

regulation of salicylic acid mediated signaling pathway [inference]

positive regulation of salicylic acid mediated signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of salicylic acid mediated signaling pathway

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of salicylic acid mediated signaling pathway

regulation of salicylic acid mediated signaling pathway [inference]

positive regulation of salicylic acid mediated signaling pathway

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of salicylic acid mediated signaling pathway

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of salicylic acid mediated signaling pathway

detoxification [inference]

cellular detoxification [inference]

cellular oxidant detoxification

Displaying **all 3** entries
GO Term	Evidence Code	PMID
plasma membrane	HDA	17644812
mitochondrion	HDA	28887381
cytosol	HDA IDA	25293756 28381499 32205453

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

membrane [inference]

plasma membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying **all 3** entries
GO Term	Evidence Code	PMID
glutathione dehydrogenase (ascorbate) activity	IDA IMP	12077129 28381499
glutathione binding	IDA	15159623
glutathione transferase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on a sulfur group of donors [inference]

disulfide oxidoreductase activity [inference]

glutathione disulfide oxidoreductase activity [inference]

glutathione dehydrogenase (ascorbate) activity

oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor [inference]

glutathione dehydrogenase (ascorbate) activity

transferase activity [inference]

transferase activity, transferring alkyl or aryl (other than methyl) groups [inference]

glutathione transferase activity

binding [inference]

ion binding [inference]

anion binding [inference]

glutathione binding

antioxidant activity [inference]

glutathione dehydrogenase (ascorbate) activity

Gene Ontology information from NCBI Gene and UniProt.

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024