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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
diacylglycerol O-acyltransferase 2
Summary
- Gene Symbol
-
- DGAT2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Acyltransferase
- Alternative splicing
- Cytoplasm
- Endoplasmic reticulum
- Glycerol metabolism
- Lipid biosynthesis
- Lipid droplet
- Reference proteome
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q96PD7 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| diacylglycerol metabolic process | ||
| cholesterol homeostasis | ||
| lipid storage | ||
| retinol metabolic process | ||
| glycerol metabolic process |
GO Hierarchy
biological process
metabolic process [inference]
nitrogen compound metabolic process [inference]
cellular metabolic process [inference]
primary metabolic process [inference]
small molecule metabolic process [inference]
organic substance metabolic process [inference]
cellular process [inference]
cellular metabolic process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| intracellular membrane-bounded organelle | ||
| endoplasmic reticulum | ||
| cytosol | ||
| lipid droplet | ||
| endoplasmic reticulum membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein homodimerization activity | ||
| diacylglycerol O-acyltransferase activity | ||
| 2-acylglycerol O-acyltransferase activity | ||
| protein binding | ||
| retinol O-fatty-acyltransferase activity |
GO Hierarchy
KEGG BRITE Database
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110152 | Charcot-Marie-Tooth disease type 1B | |
| DOID:0110153 | Charcot-Marie-Tooth disease type 1E | |
| DOID:0110154 | Charcot-Marie-Tooth disease type 2A1 | |
| DOID:0110155 | Charcot-Marie-Tooth disease type 2A2A | |
| DOID:0110156 | Charcot-Marie-Tooth disease type 2B1 | |
| DOID:0110157 | Charcot-Marie-Tooth disease type 2J | |
| DOID:0110158 | Charcot-Marie-Tooth disease type 2I | |
| DOID:0110159 | Charcot-Marie-Tooth disease type 2B | |
| DOID:0110160 | Charcot-Marie-Tooth disease axonal type 2T | |
| DOID:0110161 | Charcot-Marie-Tooth disease type 2R |
LIPID MAPS Gene / Proteome Database
- LMPD ID
- LMP005085
- Gene Name
- diacylglycerol O-acyltransferase 2
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 100914285 | SARHA09305 | ||
| 103111039 | ERIEU09513 | ||
| 100414192 | CALJA03346 | ||
| 105578724 | CERAT17379 | ||
| 102128601 | MACFA09906 | ||
| 105468770 | MACNE13081 | ||
| 101004164 | PAPAN07044 | ||
| 105555210 | MANLE33171 | ||
| 101124779 | GORGO03310 | ||
| 100987880 | PANPA07545 |
