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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
diacylglycerol O-acyltransferase 2
Summary
- Gene Symbol
-
- DGAT2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Acyltransferase
- Alternative splicing
- Cytoplasm
- Endoplasmic reticulum
- Glycerol metabolism
- Lipid biosynthesis
- Lipid droplet
- Reference proteome
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q96PD7 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| diacylglycerol metabolic process | ||
| cholesterol homeostasis | ||
| lipid storage | ||
| retinol metabolic process | ||
| glycerol metabolic process |
GO Hierarchy
biological process
metabolic process [inference]
nitrogen compound metabolic process [inference]
cellular metabolic process [inference]
primary metabolic process [inference]
small molecule metabolic process [inference]
organic substance metabolic process [inference]
cellular process [inference]
cellular metabolic process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| intracellular membrane-bounded organelle | ||
| endoplasmic reticulum | ||
| cytosol | ||
| lipid droplet | ||
| endoplasmic reticulum membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein homodimerization activity | ||
| diacylglycerol O-acyltransferase activity | ||
| 2-acylglycerol O-acyltransferase activity | ||
| protein binding | ||
| retinol O-fatty-acyltransferase activity |
GO Hierarchy
KEGG BRITE Database
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110175 | Charcot-Marie-Tooth disease axonal type 2O | |
| DOID:0110177 | Charcot-Marie-Tooth disease axonal type 2N | |
| DOID:0110179 | Charcot-Marie-Tooth disease type 2B2 | |
| DOID:0110182 | Charcot-Marie-Tooth disease axonal type 2C | |
| DOID:0110183 | Charcot-Marie-Tooth disease type 4C | |
| DOID:0110184 | Charcot-Marie-Tooth disease type 4J | |
| DOID:0110185 | Charcot-Marie-Tooth disease type 4A | |
| DOID:0110186 | Charcot-Marie-Tooth disease type 4D | |
| DOID:0110187 | Charcot-Marie-Tooth disease type 4K | |
| DOID:0110190 | Charcot-Marie-Tooth disease type 4B2 |
LIPID MAPS Gene / Proteome Database
- LMPD ID
- LMP005085
- Gene Name
- diacylglycerol O-acyltransferase 2
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 105729008 | AOTNA10545 | ||
| 110210559 | PHACI00730 | ||
| 101049433 | SAIBB06168 | ||
| 101595728 | JACJA07771 | ||
| 102432364 | MYOLU14474 | ||
| 117030228 | RHIFE30142 | ||
| 101810713 | FICAL06554 | ||
| 103248066 | CHLSB00824 | ||
| 108545121 | RHIBE41709 | ||
| 104665097 | RHIRO02775 |
