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MIRAGE
hepatitis A virus cellular receptor 2
Summary
- Gene Symbol
-
- HAVCR2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Adaptive immunity
- Alternative splicing
- Cell junction
- Cell membrane
- Disease variant
- Disulfide bond
- Glycoprotein
- Immunoglobulin domain
- Inflammatory response
- Innate immunity
- Metal-binding
- Phosphoprotein
- Reference proteome
- Signal
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q8TDQ0 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| adaptive immune response | ||
| macrophage activation involved in immune response | ||
| natural killer cell tolerance induction | ||
| regulation of tolerance induction dependent upon immune response | ||
| negative regulation of T-helper 1 type immune response |
GO Hierarchy
biological process
immune system process [inference]
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
negative regulation of immune system process [inference]
negative regulation of leukocyte activation [inference]
negative regulation of immune effector process [inference]
negative regulation of immune response [inference]
positive regulation of immune system process [inference]
regulation of leukocyte activation [inference]
negative regulation of leukocyte activation [inference]
regulation of lymphocyte activation [inference]
regulation of immune effector process [inference]
negative regulation of immune effector process [inference]
regulation of leukocyte mediated immunity [inference]
regulation of immune response [inference]
regulation of adaptive immune response [inference]
regulation of immune response to tumor cell [inference]
regulation of innate immune response [inference]
negative regulation of immune response [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of biosynthetic process [inference]
negative regulation of cellular biosynthetic process [inference]
negative regulation of macromolecule biosynthetic process [inference]
positive regulation of biosynthetic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
negative regulation of gene expression
negative regulation of macromolecule biosynthetic process [inference]
negative regulation of cellular biosynthetic process [inference]
negative regulation of macromolecule biosynthetic process [inference]
negative regulation of metabolic process [inference]
negative regulation of biosynthetic process [inference]
negative regulation of cellular biosynthetic process [inference]
negative regulation of macromolecule biosynthetic process [inference]
negative regulation of macromolecule metabolic process [inference]
negative regulation of macromolecule biosynthetic process [inference]
negative regulation of cellular metabolic process [inference]
negative regulation of cellular biosynthetic process [inference]
negative regulation of macromolecule biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
negative regulation of cellular metabolic process [inference]
negative regulation of cellular biosynthetic process [inference]
negative regulation of macromolecule biosynthetic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
negative regulation of gene expression
negative regulation of macromolecule biosynthetic process [inference]
negative regulation of cellular biosynthetic process [inference]
negative regulation of macromolecule biosynthetic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
negative regulation of gene expression
negative regulation of macromolecule biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
negative regulation of macromolecule metabolic process [inference]
negative regulation of macromolecule biosynthetic process [inference]
regulation of signaling [inference]
positive regulation of biological process [inference]
positive regulation of immune system process [inference]
positive regulation of metabolic process [inference]
positive regulation of cellular process [inference]
positive regulation of response to stimulus [inference]
negative regulation of biological process [inference]
negative regulation of immune system process [inference]
negative regulation of leukocyte activation [inference]
negative regulation of immune effector process [inference]
negative regulation of immune response [inference]
negative regulation of metabolic process [inference]
negative regulation of biosynthetic process [inference]
negative regulation of cellular biosynthetic process [inference]
negative regulation of macromolecule biosynthetic process [inference]
negative regulation of macromolecule metabolic process [inference]
negative regulation of macromolecule biosynthetic process [inference]
negative regulation of cellular metabolic process [inference]
negative regulation of cellular biosynthetic process [inference]
negative regulation of macromolecule biosynthetic process [inference]
negative regulation of cellular process [inference]
negative regulation of cellular metabolic process [inference]
negative regulation of cellular biosynthetic process [inference]
negative regulation of macromolecule biosynthetic process [inference]
negative regulation of cell activation [inference]
negative regulation of response to stimulus [inference]
negative regulation of response to biotic stimulus [inference]
negative regulation of defense response [inference]
negative regulation of response to external stimulus [inference]
negative regulation of immune response [inference]
negative regulation of multicellular organismal process [inference]
negative regulation of cytokine production [inference]
negative regulation of cell activation [inference]
regulation of response to stimulus [inference]
regulation of response to biotic stimulus [inference]
regulation of response to external stimulus [inference]
positive regulation of response to stimulus [inference]
negative regulation of response to stimulus [inference]
negative regulation of response to biotic stimulus [inference]
negative regulation of defense response [inference]
negative regulation of response to external stimulus [inference]
negative regulation of immune response [inference]
regulation of immune response [inference]
regulation of adaptive immune response [inference]
regulation of immune response to tumor cell [inference]
regulation of innate immune response [inference]
negative regulation of immune response [inference]
regulation of response to stress [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cell adhesion [inference]
regulation of cellular metabolic process [inference]
negative regulation of cellular metabolic process [inference]
negative regulation of cellular biosynthetic process [inference]
negative regulation of macromolecule biosynthetic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
negative regulation of gene expression
negative regulation of macromolecule biosynthetic process [inference]
negative regulation of cellular biosynthetic process [inference]
negative regulation of macromolecule biosynthetic process [inference]
regulation of cell killing [inference]
regulation of cell population proliferation [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
negative regulation of cellular metabolic process [inference]
negative regulation of cellular biosynthetic process [inference]
negative regulation of macromolecule biosynthetic process [inference]
negative regulation of cell activation [inference]
regulation of cell activation [inference]
regulation of leukocyte activation [inference]
negative regulation of leukocyte activation [inference]
regulation of lymphocyte activation [inference]
negative regulation of cell activation [inference]
regulation of multicellular organismal process [inference]
regulation of cytokine production [inference]
regulation of cell activation [inference]
regulation of leukocyte activation [inference]
negative regulation of leukocyte activation [inference]
regulation of lymphocyte activation [inference]
negative regulation of cell activation [inference]
positive regulation of multicellular organismal process [inference]
negative regulation of multicellular organismal process [inference]
negative regulation of cytokine production [inference]
negative regulation of cell activation [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| immunological synapse | ||
| early endosome | ||
| plasma membrane | ||
| cell surface | ||
| mediator complex |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| transmembrane signaling receptor activity | ||
| protein binding | ||
| protein binding | ||
| metal ion binding |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Hepatitis A virus cellular receptor 1
- Functional Category
-
- M: Cell wall/membrane/envelope biogenesis
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| apoptotic cell clearance |
| cytoskeletal rearrangement involved in phagocytosis, engulfment |
| phosphatidylserine binding |
| InterPro |
|---|
| Immunoglobulin V-set domain |
| Immunoglobulin subtype |
| Immunoglobulin-like domain superfamily |
| Immunoglobulin-like domain |
| Immunoglobulin-like fold |
Disease
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 84868 | ZFIN:ZDB-GENE-091204-20 | ||
| 171285 | RGD:1305233 | MOUSE04315 | |
| 286934 | ZFIN:ZDB-GENE-091204-20 | ||
| 363578 | RGD:1305233 | RATNO03263 | |
| 462219 | PANTR36683 | ||
| 479318 | CANLF14876 | ||
| 714891 | MACMU39649 | ||
| 768047 | BOVIN33824 | ||
| 100071246 | HORSE07806 | ||
| 100399869 | CALJA26877 |
