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leucine rich repeat and Ig domain containing 1

Summary

Gene Symbol

LINGO1

Organism

Homo sapiens (human)

External Links

NCBI Gene

84894

PubChem

84894

Alliance of Genome Resources

HGNC:21205

Annotation

Keyword

3D-structure
Alternative splicing
Cell membrane
Disease variant
Disulfide bond
Glycoprotein
Immunoglobulin domain
Intellectual disability
Leucine-rich repeat
Phosphoprotein
Proteomics identification
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q96FE5	Leucine-rich repeat and immunoglobulin domain-containing protein 1 Leucine-rich repeat neuronal protein 1 Leucine-rich repeat neuronal protein 6A

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
extracellular space	IBA
plasma membrane	TAS
extracellular matrix	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular space

membrane [inference]

plasma membrane

external encapsulating structure [inference]

extracellular matrix

Displaying **all 2** entries
GO Term	Evidence Code	PMID
epidermal growth factor receptor binding	IBA
protein binding	IPI	14966521 17726113 20659559 22133804 25416956 32296183 32814053

GO Hierarchy

molecular function

binding [inference]

protein binding

signaling receptor binding [inference]

growth factor receptor binding [inference]

epidermal growth factor receptor binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1

Functional Category

K: Transcription
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 9** entries
InterPro
Immunoglobulin I-set
Immunoglobulin subtype 2
Immunoglobulin subtype
Immunoglobulin-like domain superfamily
Immunoglobulin-like domain
Immunoglobulin-like fold
Leucine-rich repeat domain superfamily
Leucine-rich repeat, typical subtype
Leucine-rich repeat

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0081225	autosomal recessive intellectual developmental disorder 64	Alliance of Genome Resources
DOID:1686	glaucoma	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of **103** in total

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Species	Gene ID	Alliance of Genome Resources
Caenorhabditis elegans	10446	WB:WBGene00020693
Caenorhabditis elegans	16979	WB:WBGene00020693
Caenorhabditis elegans	16980	WB:WBGene00020693
Caenorhabditis elegans	16981	WB:WBGene00020693
Caenorhabditis elegans	17079	WB:WBGene00020693
Caenorhabditis elegans	29195	WB:WBGene00020693
Caenorhabditis elegans	54674	WB:WBGene00020693
Caenorhabditis elegans	57633	WB:WBGene00020693
Caenorhabditis elegans	60506	WB:WBGene00020693
Caenorhabditis elegans	81514	WB:WBGene00020693